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Physico-Chemical Characterisation of Lipids from Mytilus galloprovincialis (L.) and Rapana venosa and their Healing Properties on Skin Burns

, , , , , , , und . Lipids, 43 (9): 829--841 (September 2008)

Zusammenfassung

Abstract  Black Sea molluscs and gastropods are the most studied organisms from the Romanian littoral zone. In particular, those from the Mytilidae species are of great interest because biochemical investigations have shown that they can be sources of biologicalactive substances which can have different applications (e.g. food additives). We report here the extraction of lipids fromtwo different species of molluscs (Mytilus galloprovincialis L., Mediterranean mussel) and gastropods (Rapana venosa, hard-shell clam). The extracts were evaluated in terms of antioxidant and composition properties and their healing propertieswere tested on skin burns in Wistar rats. Our studies proved that the two lipid extracts contained a relatively complex distributionof compounds, in terms of characteristic indices, polyunsaturated fatty acids (PUFA) and vitamins E and D. The presence ofsuch compounds rendered the extracts very efficient in healing induced skin burns in Wistar rats. The histological analysisshowed a reduction in the time of healing (12–13 and 13–15 days for the Mytilus galloprovincialis (L.) Rapana venosa extracts, respectively) compared to 20–22 for untreated animals, based on results from tissues and blood samples. Our investigationshave been proved to be promising in terms of future potential applications of the extracts as skin-care products, cosmeticsand/or pharmaceutical preparations owing to their dermorestitutive properties.

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SpringerLink - Journal Article

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