%0 Journal Article %1 Walther.2010 %A Walther, Thomas %A Schuler, Gerhard %A Borger, Michael A. %A Kempfert, Jörg %A Seeburger, Jörg %A Rückert, Yvonne %A Ender, Jörg %A Linke, Axel %A Scholz, Markus %A Falk, Volkmar %A Mohr, Friedrich W. %D 2010 %J European heart journal %K Aged Aged,_80_and_over Aortic_Valve_Stenosis/mortality/surgery Female Heart_Valve_Prosthesis Heart_Valve_Prosthesis_Implantation/methods Humans Kaplan-Meier_Estimate Male Postoperative_Care Preoperative_Care Propensity_Score Retrospective_Studies Risk_Factors Surgical_Procedures,_Minimally_Invasive/methods/mortality Transplantation,_Heterologous Treatment_Outcome %N 11 %P 1398–1403 %T Transapical aortic valve implantation in 100 consecutive patients: comparison to propensity-matched conventional aortic valve replacement %V 31 %X AIMS\r\nTo evaluate the outcome of transapical aortic valve implantation (TA-AVI) in comparison to conventional surgery.\r\nMETHODS AND RESULTS\r\nOne hundred consecutive high-risk patients with symptomatic aortic valve stenosis received TA-AVI using the Edwards SAPIEN pericardial xenograft between February 2006 and January 2008. Patient age was 82.7 +/- 5 years, 77 were females, logistic EuroSCORE predicted risk of mortality was 29.4 +/- 13\% and Society Thoracic Surgeons score risk for mortality was 15.2 +/- 8.3\%. Propensity score analysis was used to identify a control group of patients that underwent conventional aortic valve replacement (C-AVR). Transapical aortic valve implantation was performed successfully in 97 patients, whereas three patients required early conversion. There were no new onset neurological events in the TA-AVI group and early extubation was performed in 82 patients. Echocardiography revealed good valve function with low transvalvular gradients in all patients. Thirty-day survival was 90 +/- 3 vs. 85 +/- 4\% for TA-AVI vs. C-AVR, and 1-year survival was 73 +/- 4 vs. 69 +/- 5\% (P = 0.55).\r\nCONCLUSION\r\nTransapical aortic valve implantation is a safe, minimally invasive, and off-pump technique to treat high-risk patients with aortic stenosis. Results of the initial 100 patients are good and compare favourably to conventional surgery.

@article{Walther.2010, abstract = {AIMS\r\nTo evaluate the outcome of transapical aortic valve implantation (TA-AVI) in comparison to conventional surgery.\r\nMETHODS AND RESULTS\r\nOne hundred consecutive high-risk patients with symptomatic aortic valve stenosis received TA-AVI using the Edwards SAPIEN pericardial xenograft between February 2006 and January 2008. Patient age was 82.7 +/- 5 years, 77 were females, logistic EuroSCORE predicted risk of mortality was 29.4 +/- 13\% and Society Thoracic Surgeons score risk for mortality was 15.2 +/- 8.3\%. Propensity score analysis was used to identify a control group of patients that underwent conventional aortic valve replacement (C-AVR). Transapical aortic valve implantation was performed successfully in 97 patients, whereas three patients required early conversion. There were no new onset neurological events in the TA-AVI group and early extubation was performed in 82 patients. Echocardiography revealed good valve function with low transvalvular gradients in all patients. Thirty-day survival was 90 +/- 3 vs. 85 +/- 4\% for TA-AVI vs. C-AVR, and 1-year survival was 73 +/- 4 vs. 69 +/- 5\% (P = 0.55).\r\nCONCLUSION\r\nTransapical aortic valve implantation is a safe, minimally invasive, and off-pump technique to treat high-risk patients with aortic stenosis. Results of the initial 100 patients are good and compare favourably to conventional surgery.}, added-at = {2014-10-14T15:28:14.000+0200}, author = {Walther, Thomas and Schuler, Gerhard and Borger, Michael A. and Kempfert, Jörg and Seeburger, Jörg and Rückert, Yvonne and Ender, Jörg and Linke, Axel and Scholz, Markus and Falk, Volkmar and Mohr, Friedrich W.}, biburl = {https://www.bibsonomy.org/bibtex/26c10e3fb871e42fc56b51ff28673629f/drtester}, interhash = {2e189b0926eb0cda04de7fadcd2624ea}, intrahash = {6c10e3fb871e42fc56b51ff28673629f}, journal = {European heart journal}, keywords = {Aged Aged,_80_and_over Aortic_Valve_Stenosis/mortality/surgery Female Heart_Valve_Prosthesis Heart_Valve_Prosthesis_Implantation/methods Humans Kaplan-Meier_Estimate Male Postoperative_Care Preoperative_Care Propensity_Score Retrospective_Studies Risk_Factors Surgical_Procedures,_Minimally_Invasive/methods/mortality Transplantation,_Heterologous Treatment_Outcome}, number = 11, pages = {1398–1403}, timestamp = {2014-10-14T15:28:14.000+0200}, title = {Transapical aortic valve implantation in 100 consecutive patients: comparison to propensity-matched conventional aortic valve replacement}, volume = 31, year = 2010 }