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The CancerGrid experience: Metadata-based model-driven engineering for clinical trials

, , , and . Science of Computer Programming, 89, Part B (0): 126 - 143 (2014)Special issue on Success Stories in Model Driven Engineering.
DOI: http://dx.doi.org/10.1016/j.scico.2013.02.010

Abstract

Abstract The CancerGrid approach to software support for clinical trials is based on two principles: careful curation of semantic metadata about clinical observations, to enable subsequent data integration, and model-driven generation of trial-specific software artefacts from a trial protocol, to streamline the software development process. This paper explains the approach, presents four varied case studies, and discusses the lessons learned.

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