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A case report on Azathioprine induced hepatotoxicity

, , , and . World Journal of Biology Pharmacy and Health Sciences, 14 (3): 355–358 (June 2023)
DOI: 10.30574/wjbphs.2023.14.3.0270

Abstract

The most frequent cause of acute liver failure is drug induced liver damage. The lack of diagnostic testes or biomarkers, identification of DILI is difficult one. In most cases DILI was mild and reversible. Azathioprine, is a widely used immunosupressive agent had a nature of causing liver injury but rare. It basically presents with mild symptoms. Azathioprine can cause idiosyncratic liver injury, usually presented with juandice and fatigue and then linked to elevated liver enzymes. It is reversible and typically resolveson cessation of Azathioprine. This case focuses on Azathioprine’s nature of hepatotoxicity. After the withdrawal of offending agent, it is resolved.

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