This invention also provides a method of treating atherosclerosis in a subject, comprising administering to the subject an effective amount of a substance capable of binding to the amino-terminal region of apolipoprotein B, thereby treating the atherosclerosis. This invention also provides a method for inhibiting the binding of low density lipoprotein to blood vessel matrix in a subject, comprising administering to the subject an effective amount of a substance capable of competing with the amino-terminal region of apolipoprotein B for binding to blood vessel matrix, thereby inhibiting the binding of low density lipoprotein to blood vessel matrix. This invention also provides a method for identifying a compound capable of ameliorating atherosclerosis. Additionally, this invention provides a kit for inhibiting the binding of low density lipoprotein to blood vessel matrix, wherein the kit comprises a substance capable of binding to the amino-terminal region of apolipoprotein B.
%0 Generic
%1 citeulike:495875
%A Goldberg, Ira J.
%A Pillarisetti, Sivaram
%D 1997
%J United States Patent
%K patent antibody apob
%T Method for inhibiting the binding of low density lipoprotein to blood vessel matrix
%V 6156315
%X This invention also provides a method of treating atherosclerosis in a subject, comprising administering to the subject an effective amount of a substance capable of binding to the amino-terminal region of apolipoprotein B, thereby treating the atherosclerosis. This invention also provides a method for inhibiting the binding of low density lipoprotein to blood vessel matrix in a subject, comprising administering to the subject an effective amount of a substance capable of competing with the amino-terminal region of apolipoprotein B for binding to blood vessel matrix, thereby inhibiting the binding of low density lipoprotein to blood vessel matrix. This invention also provides a method for identifying a compound capable of ameliorating atherosclerosis. Additionally, this invention provides a kit for inhibiting the binding of low density lipoprotein to blood vessel matrix, wherein the kit comprises a substance capable of binding to the amino-terminal region of apolipoprotein B.
@misc{citeulike:495875,
abstract = {This invention also provides a method of treating atherosclerosis in a subject, comprising administering to the subject an effective amount of a substance capable of binding to the amino-terminal region of apolipoprotein B, thereby treating the atherosclerosis. This invention also provides a method for inhibiting the binding of low density lipoprotein to blood vessel matrix in a subject, comprising administering to the subject an effective amount of a substance capable of competing with the amino-terminal region of apolipoprotein B for binding to blood vessel matrix, thereby inhibiting the binding of low density lipoprotein to blood vessel matrix. This invention also provides a method for identifying a compound capable of ameliorating atherosclerosis. Additionally, this invention provides a kit for inhibiting the binding of low density lipoprotein to blood vessel matrix, wherein the kit comprises a substance capable of binding to the amino-terminal region of apolipoprotein B.},
added-at = {2006-07-07T01:10:50.000+0200},
author = {Goldberg, Ira J. and Pillarisetti, Sivaram},
biburl = {https://www.bibsonomy.org/bibtex/27f7ecb39279856d6449178c5b3922cd0/biblio24},
citeulike-article-id = {495875},
institution = {The Trustees of Columbia University in the City of New York (New York, NY)},
interhash = {774392443c31bf8f16858325bb0154b8},
intrahash = {7f7ecb39279856d6449178c5b3922cd0},
journal = {United States Patent},
keywords = {patent antibody apob},
month = {November},
priority = {2},
timestamp = {2006-07-07T01:10:50.000+0200},
title = {Method for inhibiting the binding of low density lipoprotein to blood vessel matrix},
volume = 6156315,
year = 1997
}