As DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bowtie and the SNP caller SOAPsnp. Executing in parallel using Hadoop, Crossbow analyzes data comprising 38-fold coverage of the human genome in three hours using a 320-CPU cluster rented from a cloud computing service for about $85. Crossbow is available from http://bowtie-bio.sourceforge.net/crossbow/
%0 Journal Article
%1 langmead2009searching
%A Langmead, B.
%A Schatz, M.C.
%A Lin, J.
%A Pop, M.
%A Salzberg, S.L.
%D 2009
%J Genome Biol
%K bioinformatics cloud-computing snp
%N 11
%P R134
%R 10.1186/gb-2009-10-11-r134
%T Searching for SNPs with cloud computing
%V 10
%X As DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bowtie and the SNP caller SOAPsnp. Executing in parallel using Hadoop, Crossbow analyzes data comprising 38-fold coverage of the human genome in three hours using a 320-CPU cluster rented from a cloud computing service for about $85. Crossbow is available from http://bowtie-bio.sourceforge.net/crossbow/
@article{langmead2009searching,
abstract = {As DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bowtie and the SNP caller SOAPsnp. Executing in parallel using Hadoop, Crossbow analyzes data comprising 38-fold coverage of the human genome in three hours using a 320-CPU cluster rented from a cloud computing service for about $85. Crossbow is available from http://bowtie-bio.sourceforge.net/crossbow/},
added-at = {2012-04-25T13:37:59.000+0200},
author = {Langmead, B. and Schatz, M.C. and Lin, J. and Pop, M. and Salzberg, S.L.},
biburl = {https://www.bibsonomy.org/bibtex/283be4593a6773cfb459c928e4f55ea84/ytyoun},
doi = {10.1186/gb-2009-10-11-r134},
interhash = {98b734ee3764eeaf032cd1bd419e06c8},
intrahash = {83be4593a6773cfb459c928e4f55ea84},
journal = {Genome Biol},
keywords = {bioinformatics cloud-computing snp},
number = 11,
pages = {R134},
timestamp = {2016-06-14T13:29:45.000+0200},
title = {Searching for SNPs with cloud computing},
volume = 10,
year = 2009
}