%0 Journal Article %1 Christophe2000 %A Christophe, C. %A Boutemy, R. %A Christiaens, F. %A Fonteyne, C. %A Ziereisen, F. %A Dan, B. %D 2000 %J J Radiol %K Basal Ganglia Diseases; Brain Edema; Cerebral Palsy; Electroencephalography; Epilepsy; Evoked Potentials; Female; Follow-Up Studies; Hemiplegia; Humans; Hypoxia-Ischemia, Brain; Infant; Intensive Care; Magnetic Resonance Imaging; Male; Mental Retardation; Neurologic Examination; Paraplegia; Predictive Value of Tests; Prognosis; Quadriplegia; Retrospective Sudden Infant Death; Time Factors %N 1 %P 25--32 %T Value of brain MR imaging in infants with a severe idiopathic apparent life threatening event %V 81 %X OBJECTIVE: Prognostic value of a magnetic resonance imaging (MRI) scoring system in infants with a severe apparent life threatening event (ALTE). METHODS: Ten infants with an ALTE (aged between 6 and 31 weeks) were clinically graded according to the PRISM score and evaluated with EEG, evoked potentials and MRI. The 18 MRIs obtained were distributed in 3 classes according to the delay after which they were obtained; class A (n=5): within the first 48 hours after the event, class B (n=7): between day 3 and 8 and class C (n=6): between day 9 and 50. The 18 MRIs were evaluated retrospectively using a scoring system based on 3 categories of lesions: edema, basal ganglia injury and watershed injuries. Five infants died between day 2 and day 15 after the event. The five surviving infants had follow up neurodevelopmental testing after 38 to 77 months. RESULTS: There was no correlation between the 5 MRIs of class A and the neurological outcome. For the MRIs of class B and C, the scoring system can be of great value when combined with the scores of EEG, EP and PRISM. CONCLUSIONS: The scoring system for MRI performed within 48 hours after the event is falsely reassuring. MRI can be helpful as early as 3 days after the event when combined with the score of the electrophysiological investigations and the PRISM.

@article{Christophe2000, abstract = {OBJECTIVE: Prognostic value of a magnetic resonance imaging (MRI) scoring system in infants with a severe apparent life threatening event (ALTE). METHODS: Ten infants with an ALTE (aged between 6 and 31 weeks) were clinically graded according to the PRISM score and evaluated with EEG, evoked potentials and MRI. The 18 MRIs obtained were distributed in 3 classes according to the delay after which they were obtained; class A (n=5): within the first 48 hours after the event, class B (n=7): between day 3 and 8 and class C (n=6): between day 9 and 50. The 18 MRIs were evaluated retrospectively using a scoring system based on 3 categories of lesions: edema, basal ganglia injury and watershed injuries. Five infants died between day 2 and day 15 after the event. The five surviving infants had follow up neurodevelopmental testing after 38 to 77 months. RESULTS: There was no correlation between the 5 MRIs of class A and the neurological outcome. For the MRIs of class B and C, the scoring system can be of great value when combined with the scores of EEG, EP and PRISM. CONCLUSIONS: The scoring system for MRI performed within 48 hours after the event is falsely reassuring. MRI can be helpful as early as 3 days after the event when combined with the score of the electrophysiological investigations and the PRISM.}, added-at = {2014-07-19T19:15:16.000+0200}, author = {Christophe, C. and Boutemy, R. and Christiaens, F. and Fonteyne, C. and Ziereisen, F. and Dan, B.}, biburl = {https://www.bibsonomy.org/bibtex/2930d530a05b1e4ae5497d69a8d13c2bc/ar0berts}, groups = {public}, interhash = {3faad99cf5a6ad30a402b027ea2f162b}, intrahash = {930d530a05b1e4ae5497d69a8d13c2bc}, journal = {J Radiol}, keywords = {Basal Ganglia Diseases; Brain Edema; Cerebral Palsy; Electroencephalography; Epilepsy; Evoked Potentials; Female; Follow-Up Studies; Hemiplegia; Humans; Hypoxia-Ischemia, Brain; Infant; Intensive Care; Magnetic Resonance Imaging; Male; Mental Retardation; Neurologic Examination; Paraplegia; Predictive Value of Tests; Prognosis; Quadriplegia; Retrospective Sudden Infant Death; Time Factors}, month = Jan, number = 1, pages = {25--32}, pii = {MDOI-JR-01-2000-81-1-0221-0363-101019-ART6}, pmid = {10671721}, timestamp = {2014-07-19T19:15:16.000+0200}, title = {[Value of brain MR imaging in infants with a severe idiopathic apparent life threatening event]}, username = {ar0berts}, volume = 81, year = 2000 }