%0 Journal Article %1 citeulike:885140 %A Degtyarenko, K. N. %A Kulikova, T. A. %C EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, U.K. kirill@ebi.ac.uk %D 2001 %J Biochem Soc Trans %K oxygenases p450 review %N Pt 2 %P 139--147 %T Evolution of bioinorganic motifs in P450-containing systems. %U http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11356142 %V 29 %X The choice of bioinorganic motifs by Nature results in a spectacular variety of active-site structures even within the same protein family. Here, we use the concept of the bioinorganic motif to discuss the function and evolution of P450-containing and other related systems. Apart from P450, these systems include a FAD flavoprotein or domain, a FMN domain, ferredoxins and cytochrome b(5). Analysis of available complete genomes can shed light on what an ancestral P450-containing system could be.

@article{citeulike:885140, abstract = {The choice of bioinorganic motifs by Nature results in a spectacular variety of active-site structures even within the same protein family. Here, we use the concept of the bioinorganic motif to discuss the function and evolution of P450-containing and other related systems. Apart from P450, these systems include a FAD flavoprotein or domain, a FMN domain, ferredoxins and cytochrome b(5). Analysis of available complete genomes can shed light on what an ancestral P450-containing system could be.}, added-at = {2006-10-23T11:08:30.000+0200}, address = {EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, U.K. kirill@ebi.ac.uk}, author = {Degtyarenko, K. N. and Kulikova, T. A.}, biburl = {https://www.bibsonomy.org/bibtex/2956b71c50d007f0abf3cae5783d8d5a2/robert}, citeulike-article-id = {885140}, interhash = {595fdfbf7d78b07bf3f167dae3aad16b}, intrahash = {956b71c50d007f0abf3cae5783d8d5a2}, issn = {0300-5127}, journal = {Biochem Soc Trans}, keywords = {oxygenases p450 review}, month = May, number = {Pt 2}, pages = {139--147}, priority = {2}, timestamp = {2006-10-23T11:08:30.000+0200}, title = {Evolution of bioinorganic motifs in P450-containing systems.}, url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve\&db=pubmed\&dopt=Abstract\&list_uids=11356142}, volume = 29, year = 2001 }