BACKGROUND: The prevalence of gonorrhea of the pharynx among select samples of men who have sex with men (MSM) ranges from 9\% to 15\%. To our knowledge, there have been no longitudinal studies in a prospective MSM cohort to estimate pharyngeal gonorrhea incidence or predictors of infection. We examined the prevalence, incidence, and sociodemographic and behavioral predictors of pharyngeal gonorrhea in a cohort of sexually active, human immunodeficiency virus-negative MSM. METHODS: We conducted a prospective study of pharyngeal gonorrhea among MSM who were enrolled in a behavioral intervention study to prevent human immunodeficiency virus infection (Project EXPLORE). Participants were enrolled in this ancillary study from March 2001 through July 2003. At baseline and every 6 months thereafter until 31 July 2003, participants were tested for pharyngeal gonorrhea and were administered a questionnaire regarding their oral sex practices. Rectal and urethral gonorrhea testing were also performed. RESULTS: Prevalence of pharyngeal gonorrhea was 5.5\% (136 cases diagnosed from 2475 tests). The incidence rate was 11.2 cases per 100 person-years. Pharyngeal gonorrhea was positively associated with younger age and the number of insertive oral sex partners in the past 3 months. Ejaculation did not increase the risk of pharyngeal gonorrhea. Gonorrhea of the pharynx was asymptomatic in 92\% of cases. CONCLUSIONS: The pharynx is a common, asymptomatic reservoir for gonorrhea in sexually active MSM.
%0 Journal Article
%1 morris_prevalence_2006
%A Morris, Sheldon R
%A Klausner, Jeffrey D
%A Buchbinder, Susan P
%A Wheeler, Sarah L
%A Koblin, Beryl
%A Coates, Thomas
%A Chesney, Margaret
%A Colfax, Grant N
%D 2006
%J Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
%K Behavior, Diseases Diseases, Gonorrhea, Homosexuality, Humans, Incidence, Male, Neisseria Pharyngeal Prevalence, Prospective Sex, Sexual Sexually Studies, Transmitted gonorrhoeae,
%N 10
%P 1284--1289
%R 10.1086/508460
%T Prevalence and incidence of pharyngeal gonorrhea in a longitudinal sample of men who have sex with men: the EXPLORE study
%U http://www.ncbi.nlm.nih.gov/pubmed/17051493
%V 43
%X BACKGROUND: The prevalence of gonorrhea of the pharynx among select samples of men who have sex with men (MSM) ranges from 9\% to 15\%. To our knowledge, there have been no longitudinal studies in a prospective MSM cohort to estimate pharyngeal gonorrhea incidence or predictors of infection. We examined the prevalence, incidence, and sociodemographic and behavioral predictors of pharyngeal gonorrhea in a cohort of sexually active, human immunodeficiency virus-negative MSM. METHODS: We conducted a prospective study of pharyngeal gonorrhea among MSM who were enrolled in a behavioral intervention study to prevent human immunodeficiency virus infection (Project EXPLORE). Participants were enrolled in this ancillary study from March 2001 through July 2003. At baseline and every 6 months thereafter until 31 July 2003, participants were tested for pharyngeal gonorrhea and were administered a questionnaire regarding their oral sex practices. Rectal and urethral gonorrhea testing were also performed. RESULTS: Prevalence of pharyngeal gonorrhea was 5.5\% (136 cases diagnosed from 2475 tests). The incidence rate was 11.2 cases per 100 person-years. Pharyngeal gonorrhea was positively associated with younger age and the number of insertive oral sex partners in the past 3 months. Ejaculation did not increase the risk of pharyngeal gonorrhea. Gonorrhea of the pharynx was asymptomatic in 92\% of cases. CONCLUSIONS: The pharynx is a common, asymptomatic reservoir for gonorrhea in sexually active MSM.
@article{morris_prevalence_2006,
abstract = {{BACKGROUND:} The prevalence of gonorrhea of the pharynx among select samples of men who have sex with men {(MSM)} ranges from 9\% to 15\%. To our knowledge, there have been no longitudinal studies in a prospective {MSM} cohort to estimate pharyngeal gonorrhea incidence or predictors of infection. We examined the prevalence, incidence, and sociodemographic and behavioral predictors of pharyngeal gonorrhea in a cohort of sexually active, human immunodeficiency virus-negative {MSM.} {METHODS:} We conducted a prospective study of pharyngeal gonorrhea among {MSM} who were enrolled in a behavioral intervention study to prevent human immunodeficiency virus infection {(Project} {EXPLORE).} Participants were enrolled in this ancillary study from March 2001 through July 2003. At baseline and every 6 months thereafter until 31 July 2003, participants were tested for pharyngeal gonorrhea and were administered a questionnaire regarding their oral sex practices. Rectal and urethral gonorrhea testing were also performed. {RESULTS:} Prevalence of pharyngeal gonorrhea was 5.5\% (136 cases diagnosed from 2475 tests). The incidence rate was 11.2 cases per 100 person-years. Pharyngeal gonorrhea was positively associated with younger age and the number of insertive oral sex partners in the past 3 months. Ejaculation did not increase the risk of pharyngeal gonorrhea. Gonorrhea of the pharynx was asymptomatic in 92\% of cases. {CONCLUSIONS:} The pharynx is a common, asymptomatic reservoir for gonorrhea in sexually active {MSM.}},
added-at = {2011-03-11T10:05:34.000+0100},
author = {Morris, Sheldon R and Klausner, Jeffrey D and Buchbinder, Susan P and Wheeler, Sarah L and Koblin, Beryl and Coates, Thomas and Chesney, Margaret and Colfax, Grant N},
biburl = {https://www.bibsonomy.org/bibtex/2aaad812c91d5a707a82d9a802f53b2f0/jelias},
doi = {10.1086/508460},
interhash = {db01398f278847b597c4c47417490a90},
intrahash = {aaad812c91d5a707a82d9a802f53b2f0},
issn = {1537-6591},
journal = {Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America},
keywords = {Behavior, Diseases Diseases, Gonorrhea, Homosexuality, Humans, Incidence, Male, Neisseria Pharyngeal Prevalence, Prospective Sex, Sexual Sexually Studies, Transmitted gonorrhoeae,},
month = nov,
note = {{PMID:} 17051493},
number = 10,
pages = {1284--1289},
shorttitle = {Prevalence and incidence of pharyngeal gonorrhea in a longitudinal sample of men who have sex with men},
timestamp = {2011-03-11T10:06:34.000+0100},
title = {Prevalence and incidence of pharyngeal gonorrhea in a longitudinal sample of men who have sex with men: the {EXPLORE} study},
url = {http://www.ncbi.nlm.nih.gov/pubmed/17051493},
volume = 43,
year = 2006
}