This study reports the synthesis and characterization of PbMoO4
nanocrystals and the antibacterial properties and modulation of their
antibiotic activity. Lead molybdate nanocrystals were obtained through
the conventional hydrothermal method, and the structural, vibrational
and morphological properties of the sample were determined using X-ray
diffraction, Raman and infrared spectroscopy, and scanning electron
microscopy images. The obtained samples present scheelite-type
tetragonal structure (space group I4(1)/a) without secondary phases, and
the Raman spectrum shows the formation of PbMoO4 structurally ordered at
short-range, confirming the quality of the samples. The antibacterial
and antibiotic-modulation activities were performed in triplicate using
the microdilution method. The minimum inhibitory concentration (MIC) of
antibiotics alone or in association with PbMoO4, were demonstrated using geometric mean. When assayed directly, the PbMoO4 presented a MIC >=
1024 mu g/mL against all bacterial strains tested. When in association
with the gentamicin against Staphylococcus aureus, a synergism was
observed reducing 37.5% the MIC. However, in the assays against the
Gram-negative strains was observed that the presence of lead affected
the effect of the antibiotic, leading to an antagonism. (C) 2017 The
Authors. Production and hosting by Elsevier B.V. on behalf of King Saud
University.
%0 Journal Article
%1 WOS:000444265200001
%A Moura, J V B
%A Freitas, T S
%A Silva, A R P
%A Santos, A T L
%A da Silva, J H
%A Cruz, R P
%A Pereira, R L S
%A Freire, P T C
%A Luz-Lima, C
%A Pinheiro, G S
%A Coutinho, H D M
%C PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
%D 2018
%I ELSEVIER SCIENCE BV
%J ARABIAN JOURNAL OF CHEMISTRY
%K Antibacterial Characterizations; Hydrothermal method; molybdate; properties} {Lead
%N 6, SI
%P 739-746
%R 10.1016/j.arabjc.2017.12.014
%T Synthesis, characterizations, and antibacterial properties of PbMoO4
nanocrystals
%V 11
%X This study reports the synthesis and characterization of PbMoO4
nanocrystals and the antibacterial properties and modulation of their
antibiotic activity. Lead molybdate nanocrystals were obtained through
the conventional hydrothermal method, and the structural, vibrational
and morphological properties of the sample were determined using X-ray
diffraction, Raman and infrared spectroscopy, and scanning electron
microscopy images. The obtained samples present scheelite-type
tetragonal structure (space group I4(1)/a) without secondary phases, and
the Raman spectrum shows the formation of PbMoO4 structurally ordered at
short-range, confirming the quality of the samples. The antibacterial
and antibiotic-modulation activities were performed in triplicate using
the microdilution method. The minimum inhibitory concentration (MIC) of
antibiotics alone or in association with PbMoO4, were demonstrated using geometric mean. When assayed directly, the PbMoO4 presented a MIC >=
1024 mu g/mL against all bacterial strains tested. When in association
with the gentamicin against Staphylococcus aureus, a synergism was
observed reducing 37.5% the MIC. However, in the assays against the
Gram-negative strains was observed that the presence of lead affected
the effect of the antibiotic, leading to an antagonism. (C) 2017 The
Authors. Production and hosting by Elsevier B.V. on behalf of King Saud
University.
@article{WOS:000444265200001,
abstract = {This study reports the synthesis and characterization of PbMoO4
nanocrystals and the antibacterial properties and modulation of their
antibiotic activity. Lead molybdate nanocrystals were obtained through
the conventional hydrothermal method, and the structural, vibrational
and morphological properties of the sample were determined using X-ray
diffraction, Raman and infrared spectroscopy, and scanning electron
microscopy images. The obtained samples present scheelite-type
tetragonal structure (space group I4(1)/a) without secondary phases, and
the Raman spectrum shows the formation of PbMoO4 structurally ordered at
short-range, confirming the quality of the samples. The antibacterial
and antibiotic-modulation activities were performed in triplicate using
the microdilution method. The minimum inhibitory concentration (MIC) of
antibiotics alone or in association with PbMoO4, were demonstrated using geometric mean. When assayed directly, the PbMoO4 presented a MIC >=
1024 mu g/mL against all bacterial strains tested. When in association
with the gentamicin against Staphylococcus aureus, a synergism was
observed reducing 37.5% the MIC. However, in the assays against the
Gram-negative strains was observed that the presence of lead affected
the effect of the antibiotic, leading to an antagonism. (C) 2017 The
Authors. Production and hosting by Elsevier B.V. on behalf of King Saud
University.},
added-at = {2022-05-23T20:00:14.000+0200},
address = {PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS},
author = {Moura, J V B and Freitas, T S and Silva, A R P and Santos, A T L and da Silva, J H and Cruz, R P and Pereira, R L S and Freire, P T C and Luz-Lima, C and Pinheiro, G S and Coutinho, H D M},
biburl = {https://www.bibsonomy.org/bibtex/2ab80fadbcf3d74222669a57c41e955ac/ppgfis_ufc_br},
doi = {10.1016/j.arabjc.2017.12.014},
interhash = {51d5109ef738cba46c12f0c10fcd60e0},
intrahash = {ab80fadbcf3d74222669a57c41e955ac},
issn = {1878-5352},
journal = {ARABIAN JOURNAL OF CHEMISTRY},
keywords = {Antibacterial Characterizations; Hydrothermal method; molybdate; properties} {Lead},
number = {6, SI},
pages = {739-746},
publisher = {ELSEVIER SCIENCE BV},
pubstate = {published},
timestamp = {2022-05-23T20:00:14.000+0200},
title = {Synthesis, characterizations, and antibacterial properties of PbMoO4
nanocrystals},
tppubtype = {article},
volume = 11,
year = 2018
}