%0 Journal Article %1 hengartner_port--cath_2004 %A Hengartner, H %A Berger, C %A Nadal, D %A Niggli, F K %A Grotzer, M A %D 2004 %J European Journal of Cancer (Oxford, England: 1990) %K Adolescent, Bacterial Catheterization, Catheters, Central Child, Contamination, Equipment Factors Humans, Indwelling, Infant, Infections, Neoplasms, Newborn, Preschool, Retrospective Risk Studies, Venous, {Follow-Up} %N 16 %P 2452--2458 %R 10.1016/j.ejca.2004.07.017 %T Port-A-Cath infections in children with cancer %U http://www.ncbi.nlm.nih.gov/pubmed/15519519 %V 40 %X Implanted subcutaneous (s.c.) central venous port accesses including Port-A-Cath (PAC) facilitate the administration of chemotherapy or blood products and are frequently used in children with cancer. The incidence of PAC-related infections was determined in 155 consecutive paediatric cancer patients with PAC followed for a total of 134,773 days (median, 738; range, 25-2080). Overall, 48 bloodstream infections occurred in 26 patients. 12 (25\%) of these infections and 3 local infections at the insertion site were treatment-resistant and demanded removal of the PAC. Coagulase-negative staphylococci were involved in 12 of these 15 episodes. The rate of clearly PAC-related infections in this so far largest reported series was 0.11 episodes per 1000 PAC days, one of the lowest in the literature. Although catheter-related infections demanded PAC removal in 8\% of our patients, the long periods PAC were in use and their benefits argue for continued PAC use in the paediatric cancer population.

@article{hengartner_port--cath_2004, abstract = {Implanted subcutaneous (s.c.) central venous port accesses including {Port-A-Cath} {(PAC)} facilitate the administration of chemotherapy or blood products and are frequently used in children with cancer. The incidence of {PAC-related} infections was determined in 155 consecutive paediatric cancer patients with {PAC} followed for a total of 134,773 days (median, 738; range, 25-2080). Overall, 48 bloodstream infections occurred in 26 patients. 12 (25\%) of these infections and 3 local infections at the insertion site were treatment-resistant and demanded removal of the {PAC.} Coagulase-negative staphylococci were involved in 12 of these 15 episodes. The rate of clearly {PAC-related} infections in this so far largest reported series was 0.11 episodes per 1000 {PAC} days, one of the lowest in the literature. Although catheter-related infections demanded {PAC} removal in 8\% of our patients, the long periods {PAC} were in use and their benefits argue for continued {PAC} use in the paediatric cancer population.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {Hengartner, H and Berger, C and Nadal, D and Niggli, F K and Grotzer, M A}, biburl = {https://www.bibsonomy.org/bibtex/2b0426cc12f8c8fb5665cfdd5283ad349/jelias}, doi = {10.1016/j.ejca.2004.07.017}, interhash = {037e99ddbe0849f980670c0ea0e7df4d}, intrahash = {b0426cc12f8c8fb5665cfdd5283ad349}, issn = {0959-8049}, journal = {European Journal of Cancer {(Oxford,} England: 1990)}, keywords = {Adolescent, Bacterial Catheterization, Catheters, Central Child, Contamination, Equipment Factors Humans, Indwelling, Infant, Infections, Neoplasms, Newborn, Preschool, Retrospective Risk Studies, Venous, {Follow-Up}}, month = nov, note = {{PMID:} 15519519}, number = 16, pages = {2452--2458}, timestamp = {2011-03-11T10:05:50.000+0100}, title = {{Port-A-Cath} infections in children with cancer}, url = {http://www.ncbi.nlm.nih.gov/pubmed/15519519}, volume = 40, year = 2004 }