IDENTIFICATION OF CONSERVED FUNCTIONAL MOTIFS IN LACTOFERRIN
USING MEME
S. Rana. International Journal on Bioinformatics & Biosciences (IJBB), Volume 2 (Number 4):
29-36(December 2012)
DOI: 10.5121/ijbb.2012.2403
Abstract
Lactoferrin is an iron binding globular protein with antimicrobial activity was firstly isolated in bovine milk. Lactoferrin (LF) is structurally similar to the transferrins. So it is also known as lactotransferrin (LTF) is a globular multifunctional protein. Our work was on motif discovery by using OOPS modal of MEME (Multiple EM for Motif Elicitation) tool. The aim of motif discovery is to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. We have taken fifteen LTF AA
sequencesfrom different resources.By analysis of these sequences, three motifs were retrieved. It is to be noted that all fifteen sequences contains all three motifs but start points of those are different. Each motif has 15 sites and 50 widths. On the bases of motif analysis, it is distinct that LTF retrieved from any milk recourse, have common conserved patterns.
%0 Journal Article
%1 noauthororeditor
%A Rana, Shashank
%D 2012
%J International Journal on Bioinformatics & Biosciences (IJBB)
%K Conserved LTF MAST MEME OOPS pattern
%N Number 4
%P 29-36
%R 10.5121/ijbb.2012.2403
%T IDENTIFICATION OF CONSERVED FUNCTIONAL MOTIFS IN LACTOFERRIN
USING MEME
%U https://wireilla.com/papers/ijbb/V2N4/2412ijbb03.pdf
%V Volume 2
%X Lactoferrin is an iron binding globular protein with antimicrobial activity was firstly isolated in bovine milk. Lactoferrin (LF) is structurally similar to the transferrins. So it is also known as lactotransferrin (LTF) is a globular multifunctional protein. Our work was on motif discovery by using OOPS modal of MEME (Multiple EM for Motif Elicitation) tool. The aim of motif discovery is to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. We have taken fifteen LTF AA
sequencesfrom different resources.By analysis of these sequences, three motifs were retrieved. It is to be noted that all fifteen sequences contains all three motifs but start points of those are different. Each motif has 15 sites and 50 widths. On the bases of motif analysis, it is distinct that LTF retrieved from any milk recourse, have common conserved patterns.
@article{noauthororeditor,
abstract = {Lactoferrin is an iron binding globular protein with antimicrobial activity was firstly isolated in bovine milk. Lactoferrin (LF) is structurally similar to the transferrins. So it is also known as lactotransferrin (LTF) is a globular multifunctional protein. Our work was on motif discovery by using OOPS modal of MEME (Multiple EM for Motif Elicitation) tool. The aim of motif discovery is to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. We have taken fifteen LTF AA
sequencesfrom different resources.By analysis of these sequences, three motifs were retrieved. It is to be noted that all fifteen sequences contains all three motifs but start points of those are different. Each motif has 15 sites and 50 widths. On the bases of motif analysis, it is distinct that LTF retrieved from any milk recourse, have common conserved patterns.
},
added-at = {2018-09-21T07:58:44.000+0200},
author = {Rana, Shashank},
biburl = {https://www.bibsonomy.org/bibtex/2b0ec3750427fbf0ce375474fa2ea6584/jack-12},
doi = {10.5121/ijbb.2012.2403},
interhash = {0d1b9f5ed007003fbd7146aa91e40a72},
intrahash = {b0ec3750427fbf0ce375474fa2ea6584},
issn = {1839-9614},
journal = {International Journal on Bioinformatics & Biosciences (IJBB)},
keywords = {Conserved LTF MAST MEME OOPS pattern},
language = {english},
month = {December},
number = { Number 4},
pages = {29-36},
timestamp = {2018-09-21T07:58:44.000+0200},
title = {IDENTIFICATION OF CONSERVED FUNCTIONAL MOTIFS IN LACTOFERRIN
USING MEME },
url = {https://wireilla.com/papers/ijbb/V2N4/2412ijbb03.pdf},
volume = {Volume 2},
year = 2012
}