Abstract In large populations, the distribution of the trajectory of allele frequencies under selection and genetic drift approaches a semi-deterministic behavior: a deterministic trajectory started and ended at stochastic boundary values. This provides simple yet accurate approximations for the distribution of allelic frequencies over time (conditional on fixation), and of extinction and fixation times, for both hard and soft sweeps, and under arbitrary inbreeding and dominance.
%0 Journal Article
%1 martin2015simple
%A Martin, Guillaume
%A Lambert, Amaury
%D 2015
%J Theoretical Population Biology
%K diffusion_approximation fixation fixation_probability large_population_limit population_genetics selection sojourn_time
%N 0
%P 40 - 46
%R http://dx.doi.org/10.1016/j.tpb.2015.01.004
%T A simple, semi-deterministic approximation to the distribution of selective sweeps in large populations
%U http://www.sciencedirect.com/science/article/pii/S0040580915000143
%V 101
%X Abstract In large populations, the distribution of the trajectory of allele frequencies under selection and genetic drift approaches a semi-deterministic behavior: a deterministic trajectory started and ended at stochastic boundary values. This provides simple yet accurate approximations for the distribution of allelic frequencies over time (conditional on fixation), and of extinction and fixation times, for both hard and soft sweeps, and under arbitrary inbreeding and dominance.
@article{martin2015simple,
abstract = {Abstract In large populations, the distribution of the trajectory of allele frequencies under selection and genetic drift approaches a semi-deterministic behavior: a deterministic trajectory started and ended at stochastic boundary values. This provides simple yet accurate approximations for the distribution of allelic frequencies over time (conditional on fixation), and of extinction and fixation times, for both hard and soft sweeps, and under arbitrary inbreeding and dominance. },
added-at = {2015-05-01T07:03:38.000+0200},
author = {Martin, Guillaume and Lambert, Amaury},
biburl = {https://www.bibsonomy.org/bibtex/2c1c6d4d0dbe43d9d5902b85d65b3795e/peter.ralph},
doi = {http://dx.doi.org/10.1016/j.tpb.2015.01.004},
interhash = {58782c3c67cebb528b342c41634d072d},
intrahash = {c1c6d4d0dbe43d9d5902b85d65b3795e},
issn = {0040-5809},
journal = {Theoretical Population Biology },
keywords = {diffusion_approximation fixation fixation_probability large_population_limit population_genetics selection sojourn_time},
number = 0,
pages = {40 - 46},
timestamp = {2015-05-01T07:03:38.000+0200},
title = {A simple, semi-deterministic approximation to the distribution of selective sweeps in large populations },
url = {http://www.sciencedirect.com/science/article/pii/S0040580915000143},
volume = 101,
year = 2015
}