Tumor vascular networks look different from normal vascular networks, but the mechanisms underlying these differences are not known. By studying the scale-invariant behavior of normal and tumor vascular networks we show that vascular networks exhibit three classes of fractal behavior. Tumor networks display percolationlike scaling. Normal arteriovenous networks display diffusion-limited scaling, and normal capillary networks are compact structures. The mechanisms responsible for these differences are suggested using a growth model.
%0 Journal Article
%1 citeulike:7177380
%A Gazit, Yuval
%A Berk, David A.
%A Leunig, Michael
%A Baxter, Laurence T.
%A Jain, Rakesh K.
%D 1995
%I American Physical Society
%J Physical Review Letters
%K cancer, citeulikeExport hydraulics, medical
%N 12
%P 2428--2431
%R 10.1103/physrevlett.75.2428
%T Scale-Invariant Behavior and Vascular Network Formation in Normal and Tumor Tissue
%U http://dx.doi.org/10.1103/physrevlett.75.2428
%V 75
%X Tumor vascular networks look different from normal vascular networks, but the mechanisms underlying these differences are not known. By studying the scale-invariant behavior of normal and tumor vascular networks we show that vascular networks exhibit three classes of fractal behavior. Tumor networks display percolationlike scaling. Normal arteriovenous networks display diffusion-limited scaling, and normal capillary networks are compact structures. The mechanisms responsible for these differences are suggested using a growth model.
@article{citeulike:7177380,
abstract = {{Tumor vascular networks look different from normal vascular networks, but the mechanisms underlying these differences are not known. By studying the scale-invariant behavior of normal and tumor vascular networks we show that vascular networks exhibit three classes of fractal behavior. Tumor networks display percolationlike scaling. Normal arteriovenous networks display diffusion-limited scaling, and normal capillary networks are compact structures. The mechanisms responsible for these differences are suggested using a growth model.}},
added-at = {2019-03-31T01:14:40.000+0100},
author = {Gazit, Yuval and Berk, David A. and Leunig, Michael and Baxter, Laurence T. and Jain, Rakesh K.},
biburl = {https://www.bibsonomy.org/bibtex/2e8e8c6df0c1ffd00dde546ce73fa31fa/dianella},
citeulike-article-id = {7177380},
citeulike-linkout-0 = {http://dx.doi.org/10.1103/physrevlett.75.2428},
citeulike-linkout-1 = {http://link.aps.org/abstract/PRL/v75/i12/p2428},
citeulike-linkout-2 = {http://link.aps.org/pdf/PRL/v75/i12/p2428},
doi = {10.1103/physrevlett.75.2428},
interhash = {43c40e4c07e56def15fe2263c22de2ac},
intrahash = {e8e8c6df0c1ffd00dde546ce73fa31fa},
journal = {Physical Review Letters},
keywords = {cancer, citeulikeExport hydraulics, medical},
month = sep,
number = 12,
pages = {2428--2431},
posted-at = {2010-05-17 03:04:27},
priority = {2},
publisher = {American Physical Society},
timestamp = {2019-03-31T01:16:26.000+0100},
title = {{Scale-Invariant Behavior and Vascular Network Formation in Normal and Tumor Tissue}},
url = {http://dx.doi.org/10.1103/physrevlett.75.2428},
volume = 75,
year = 1995
}