Characterization of nucleoside and non-nucleoside human immunodeficiency
virus (HIV) reverse transcriptase inhibitors conformers, NRTIs and
NNRTIs, respectively, is fundamental for an improved treatment of
infected individuals. Three conformers in lamivudine I powder are
quickly identified in this work by assignment of some Raman peaks to
their vibrational frequencies, as obtained by first principles quantum
chemical calculations. The method is proposed as a practical procedure
for non-destructive identification, analysis, and process monitoring of
NRTIs and NNRTIs conformers. (c) 2007 Elsevier B.V. All rights reserved.
%0 Journal Article
%1 WOS:000246008300044
%A Pereira, B G
%A Vianna-Soares, C D
%A Righi, A
%A Pinheiro, M V B
%A Flores, M Z S
%A Bezerra, E M
%A Freire, V N
%A Lemos, V
%A Caetano, E W S
%A Cavada, B S
%C PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
%D 2007
%I ELSEVIER SCIENCE BV
%J JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
%K 3-oxathiolanyl)]cytosine} Raman `(1, `-hydroximetiol-5 cis-1{[}2 conformers; density functional human immunodeficiency modes; spectrum; theory; vibrational virus; {lamivudine;
%N 5
%P 1885-1889
%R 10.1016/j.jpba.2007.01.014
%T Identification of lamivudine conformers by Raman scattering measurements
and quantum chemical calculations
%V 43
%X Characterization of nucleoside and non-nucleoside human immunodeficiency
virus (HIV) reverse transcriptase inhibitors conformers, NRTIs and
NNRTIs, respectively, is fundamental for an improved treatment of
infected individuals. Three conformers in lamivudine I powder are
quickly identified in this work by assignment of some Raman peaks to
their vibrational frequencies, as obtained by first principles quantum
chemical calculations. The method is proposed as a practical procedure
for non-destructive identification, analysis, and process monitoring of
NRTIs and NNRTIs conformers. (c) 2007 Elsevier B.V. All rights reserved.
@article{WOS:000246008300044,
abstract = {Characterization of nucleoside and non-nucleoside human immunodeficiency
virus (HIV) reverse transcriptase inhibitors conformers, NRTIs and
NNRTIs, respectively, is fundamental for an improved treatment of
infected individuals. Three conformers in lamivudine I powder are
quickly identified in this work by assignment of some Raman peaks to
their vibrational frequencies, as obtained by first principles quantum
chemical calculations. The method is proposed as a practical procedure
for non-destructive identification, analysis, and process monitoring of
NRTIs and NNRTIs conformers. (c) 2007 Elsevier B.V. All rights reserved.},
added-at = {2022-05-23T20:00:14.000+0200},
address = {PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS},
author = {Pereira, B G and Vianna-Soares, C D and Righi, A and Pinheiro, M V B and Flores, M Z S and Bezerra, E M and Freire, V N and Lemos, V and Caetano, E W S and Cavada, B S},
biburl = {https://www.bibsonomy.org/bibtex/2efc3c86b275a82e02f38b1d1ef9f7a12/ppgfis_ufc_br},
doi = {10.1016/j.jpba.2007.01.014},
interhash = {569b23a4000563970bf1e992838cd94e},
intrahash = {efc3c86b275a82e02f38b1d1ef9f7a12},
issn = {0731-7085},
journal = {JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS},
keywords = {3-oxathiolanyl)]cytosine} Raman `(1, `-hydroximetiol-5 cis-1{[}2 conformers; density functional human immunodeficiency modes; spectrum; theory; vibrational virus; {lamivudine;},
number = 5,
pages = {1885-1889},
publisher = {ELSEVIER SCIENCE BV},
pubstate = {published},
timestamp = {2022-05-23T20:00:14.000+0200},
title = {Identification of lamivudine conformers by Raman scattering measurements
and quantum chemical calculations},
tppubtype = {article},
volume = 43,
year = 2007
}