<p>This study systematically examined the efficacy and safety of psychopharmacological and non-psychopharmacological treatments for anxiety in youth with autism spectrum disorders (ASD). Four psychopharmacological, nine cognitive behavioral therapy (CBT), and two alternative treatment studies met inclusion criteria. Psychopharmacological studies were descriptive or open label, sometimes did not specify the anxiety phenotype, and reported behavioral activation. Citalopram and buspirone yielded some improvement, whereas fluvoxamine did not. Non-psychopharmacological studies were mainly randomized controlled trials (RCTs) with CBT demonstrating moderate efficacy for anxiety disorders in youth with high functioning ASD. Deep pressure and neurofeedback provided some benefit. All studies were short-term and included small sample sizes. Large scale and long term RCTs examining psychopharmacological and non-psychopharmacological treatments are sorely needed.</p>
%0 Journal Article
%1 1421
%A Vasa, Roma A.
%A Carroll, Laura M
%A Nozzolillo, Alixandra A
%A Mahajan, Rajneesh
%A Mazurek, Micah O
%A Bennett, Amanda E
%A Wink, Logan K
%A Bernal, Maria Pilar
%D 2014
%J Journal of Autism and Developmental Disorders
%K Adolescent, Anxiety, Child Child, Citalopram, Clinical Cognitive Development Disorders, Humans, Outcome Pervasive, Therapy, Topic, Treatment Trials airp, as
%P 3215-29
%R 10.1007/s10803-014-2184-9
%T A systematic review of treatments for anxiety in youth with autism spectrum disorders.
%V 44
%X <p>This study systematically examined the efficacy and safety of psychopharmacological and non-psychopharmacological treatments for anxiety in youth with autism spectrum disorders (ASD). Four psychopharmacological, nine cognitive behavioral therapy (CBT), and two alternative treatment studies met inclusion criteria. Psychopharmacological studies were descriptive or open label, sometimes did not specify the anxiety phenotype, and reported behavioral activation. Citalopram and buspirone yielded some improvement, whereas fluvoxamine did not. Non-psychopharmacological studies were mainly randomized controlled trials (RCTs) with CBT demonstrating moderate efficacy for anxiety disorders in youth with high functioning ASD. Deep pressure and neurofeedback provided some benefit. All studies were short-term and included small sample sizes. Large scale and long term RCTs examining psychopharmacological and non-psychopharmacological treatments are sorely needed.</p>
@article{1421,
abstract = {<p>This study systematically examined the efficacy and safety of psychopharmacological and non-psychopharmacological treatments for anxiety in youth with autism spectrum disorders (ASD). Four psychopharmacological, nine cognitive behavioral therapy (CBT), and two alternative treatment studies met inclusion criteria. Psychopharmacological studies were descriptive or open label, sometimes did not specify the anxiety phenotype, and reported behavioral activation. Citalopram and buspirone yielded some improvement, whereas fluvoxamine did not. Non-psychopharmacological studies were mainly randomized controlled trials (RCTs) with CBT demonstrating moderate efficacy for anxiety disorders in youth with high functioning ASD. Deep pressure and neurofeedback provided some benefit. All studies were short-term and included small sample sizes. Large scale and long term RCTs examining psychopharmacological and non-psychopharmacological treatments are sorely needed.</p>},
added-at = {2021-02-17T03:07:48.000+0100},
author = {Vasa, Roma A. and Carroll, Laura M and Nozzolillo, Alixandra A and Mahajan, Rajneesh and Mazurek, Micah O and Bennett, Amanda E and Wink, Logan K and Bernal, Maria Pilar},
biburl = {https://www.bibsonomy.org/bibtex/2f79a13ed43795a276a1bf7a98f09dc37/acn},
doi = {10.1007/s10803-014-2184-9},
interhash = {2d033215db9a4e347154e8ca50bbed28},
intrahash = {f79a13ed43795a276a1bf7a98f09dc37},
issn = {1573-3432},
journal = {Journal of Autism and Developmental Disorders},
keywords = {Adolescent, Anxiety, Child Child, Citalopram, Clinical Cognitive Development Disorders, Humans, Outcome Pervasive, Therapy, Topic, Treatment Trials airp, as},
month = {2014 Dec},
pages = {3215-29},
timestamp = {2021-02-17T03:08:36.000+0100},
title = {A systematic review of treatments for anxiety in youth with autism spectrum disorders.},
volume = 44,
year = 2014
}