Strategies in treatment of movement disorders are discussed with the illustration of three patients with dystonia. Pharmacotherapy can be applied in two ways: (1) a precise directed therapy, or (2) a 'shotgun' approach. Botulinum toxin is successfully injected in focal and segmental forms of movement disorders. Stereotactic neurosurgery can be considered in pharmacotherapy-resistant dystonias, but also in other forms of movement disorders. Intrathecal baclophen treatment by continuous infusion is only indicated in severe forms of spasticity.
%0 Journal Article
%1 Speelman2005
%A Speelman, J. D.
%D 2005
%J J Inherit Metab Dis
%K Adult; Botulinum Toxins; Cerebral Palsy; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Female; Hand; Humans; Male; Movement Disorders; Neurosurgical Procedures; Physical Therapy Modalities
%N 3
%P 441--444
%R 10.1007/s10545-005-8049-9
%T Treatment strategies in movement disorders.
%U http://dx.doi.org/10.1007/s10545-005-8049-9
%V 28
%X Strategies in treatment of movement disorders are discussed with the illustration of three patients with dystonia. Pharmacotherapy can be applied in two ways: (1) a precise directed therapy, or (2) a 'shotgun' approach. Botulinum toxin is successfully injected in focal and segmental forms of movement disorders. Stereotactic neurosurgery can be considered in pharmacotherapy-resistant dystonias, but also in other forms of movement disorders. Intrathecal baclophen treatment by continuous infusion is only indicated in severe forms of spasticity.
@article{Speelman2005,
abstract = {Strategies in treatment of movement disorders are discussed with the illustration of three patients with dystonia. Pharmacotherapy can be applied in two ways: (1) a precise directed therapy, or (2) a 'shotgun' approach. Botulinum toxin is successfully injected in focal and segmental forms of movement disorders. Stereotactic neurosurgery can be considered in pharmacotherapy-resistant dystonias, but also in other forms of movement disorders. Intrathecal baclophen treatment by continuous infusion is only indicated in severe forms of spasticity.},
added-at = {2014-07-19T21:22:47.000+0200},
author = {Speelman, J. D.},
biburl = {https://www.bibsonomy.org/bibtex/2fd96890c19e917c41151912de963a24d/ar0berts},
doi = {10.1007/s10545-005-8049-9},
groups = {public},
interhash = {d02c1516b4f3489925fb4767a8e31303},
intrahash = {fd96890c19e917c41151912de963a24d},
journal = {J Inherit Metab Dis},
keywords = {Adult; Botulinum Toxins; Cerebral Palsy; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Female; Hand; Humans; Male; Movement Disorders; Neurosurgical Procedures; Physical Therapy Modalities},
number = 3,
pages = {441--444},
pmid = {15868476},
timestamp = {2014-07-19T21:22:47.000+0200},
title = {Treatment strategies in movement disorders.},
url = {http://dx.doi.org/10.1007/s10545-005-8049-9},
username = {ar0berts},
volume = 28,
year = 2005
}