%0 Journal Article %1 Szew_1998_49 %A Szewczyk, A. %D 1998 %J Mol. Membr. Biol. %K 9724922 Animals, Cell Channels, Chloride Cytoplasmic Gov't, Granules, Humans, Membrane, Mitochondria, Non-U.S. Nucleus, Potassium Research Reticulum, Sarcoplasmic Support, %N 2 %P 49--58 %T The intracellular potassium and chloride channels: properties, pharmacology and function (review). %V 15 %X Channels selective for potassium or chloride ions are present in membranes of intracellular organelles such as sarcoplasmic (endoplasmic) reticulum, mitochondria, nucleus, synaptic vesicles, and chromaffin, and zymogen granules. They probably play an important role in cellular events such as compensation of electrical charges during transport of Ca$^2+$, delta pH formation in mitochondria or V-ATPase containing membrane granules, and regulation of volume changes, due to potassium and chloride transport into intracellular organelles. Intracellular potassium and chloride channels could also be the target for pharmacologically active compounds. This mini-review describes the basic properties, pharmacology, and current hypotheses concerning the functional role of intracellular potassium and chloride channels.

@article{Szew_1998_49, abstract = {Channels selective for potassium or chloride ions are present in membranes of intracellular organelles such as sarcoplasmic (endoplasmic) reticulum, mitochondria, nucleus, synaptic vesicles, and chromaffin, and zymogen granules. They probably play an important role in cellular events such as compensation of electrical charges during transport of {C}a$^{2+}$, delta pH formation in mitochondria or V-ATPase containing membrane granules, and regulation of volume changes, due to potassium and chloride transport into intracellular organelles. Intracellular potassium and chloride channels could also be the target for pharmacologically active compounds. This mini-review describes the basic properties, pharmacology, and current hypotheses concerning the functional role of intracellular potassium and chloride channels.}, added-at = {2009-06-03T11:20:58.000+0200}, author = {Szewczyk, A.}, biburl = {https://www.bibsonomy.org/bibtex/2b7e97583f3326faafd152680cb400015/hake}, description = {The whole bibliography file I use.}, file = {Szew_1998_49.pdf:Szew_1998_49.pdf:PDF}, interhash = {336c658a274b1afc13f64b3908029a72}, intrahash = {b7e97583f3326faafd152680cb400015}, journal = {Mol. Membr. Biol.}, key = 208, keywords = {9724922 Animals, Cell Channels, Chloride Cytoplasmic Gov't, Granules, Humans, Membrane, Mitochondria, Non-U.S. Nucleus, Potassium Research Reticulum, Sarcoplasmic Support,}, number = 2, pages = {49--58}, pmid = {9724922}, timestamp = {2009-06-03T11:21:33.000+0200}, title = {The intracellular potassium and chloride channels: properties, pharmacology and function (review).}, volume = 15, year = 1998 }