%0 Journal Article %1 Finnstroem1998 %A Finnstroem, O. %A Olausson, P. Otterblad %A Sedin, G. %A Serenius, F. %A Svenningsen, N. %A Thiringer, K. %A Tunell, R. %A Wesstrom, G. %D 1998 %J Acta Paediatr %K Birth Weight; Central Nervous System Diseases; Cerebral Hemorrhage; Palsy; Developmental Disabilities; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Very Low Prospective Sweden %N 10 %P 1055--1060 %T Neurosensory outcome and growth at three years in extremely low birthweight infants: follow-up results from the Swedish national prospective study. %V 87 %X A prospective national investigation comprising 633 extremely low birthweight (ELBW) infants born alive in the 2-y period 1990-1992 with a birthweight of < or = 1000 g and gestational age of > or = 23 completed weeks was conducted regarding neurosensory outcome and growth. Three-hundred and sixty-two (98\%) surviving ELBW infants were assessed at a median age of 36 months, using a specially designed protocol. At follow-up, mean height, weight and head circumference in both boys and girls were significantly lower than the reference values. The incidence of cerebral palsy was 7\% among all children and 14\%, 10\% and 3\% in children born at 23-24, 25-26 and > or = 27 gestational weeks, respectively. At least one obvious handicap was present in 14\%, 9\% and 3\% of these three groups of children, respectively. After adjustment for gestational age, a significantly increased risk of handicap was found in children with intraventricular haemorrhage grade > or = 3 and/or periventricular leucomalacia and in children with retinopathy of prematurity stage > or = 3. The results show that more than 90\% of ELBW children born at > or = 25 completed gestational weeks were without neurosensory handicap at 36 months of corrected age. In infants born at 23-24 weeks of gestation, both survival and long-term outcome were less favourable.

@article{Finnstroem1998, abstract = {A prospective national investigation comprising 633 extremely low birthweight (ELBW) infants born alive in the 2-y period 1990-1992 with a birthweight of < or = 1000 g and gestational age of > or = 23 completed weeks was conducted regarding neurosensory outcome and growth. Three-hundred and sixty-two (98\%) surviving ELBW infants were assessed at a median age of 36 months, using a specially designed protocol. At follow-up, mean height, weight and head circumference in both boys and girls were significantly lower than the reference values. The incidence of cerebral palsy was 7\% among all children and 14\%, 10\% and 3\% in children born at 23-24, 25-26 and > or = 27 gestational weeks, respectively. At least one obvious handicap was present in 14\%, 9\% and 3\% of these three groups of children, respectively. After adjustment for gestational age, a significantly increased risk of handicap was found in children with intraventricular haemorrhage grade > or = 3 and/or periventricular leucomalacia and in children with retinopathy of prematurity stage > or = 3. The results show that more than 90\% of ELBW children born at > or = 25 completed gestational weeks were without neurosensory handicap at 36 months of corrected age. In infants born at 23-24 weeks of gestation, both survival and long-term outcome were less favourable.}, added-at = {2014-07-19T19:28:16.000+0200}, author = {Finnstroem, O. and Olausson, P. Otterblad and Sedin, G. and Serenius, F. and Svenningsen, N. and Thiringer, K. and Tunell, R. and Wesstrom, G.}, biburl = {https://www.bibsonomy.org/bibtex/2792633eb3bfe6a715c0f194f4c31e3e4/ar0berts}, groups = {public}, interhash = {347e5b1f4adbe6a410b38591d3f3df8d}, intrahash = {792633eb3bfe6a715c0f194f4c31e3e4}, journal = {Acta Paediatr}, keywords = {Birth Weight; Central Nervous System Diseases; Cerebral Hemorrhage; Palsy; Developmental Disabilities; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Very Low Prospective Sweden}, month = Oct, number = 10, pages = {1055--1060}, pmid = {9825972}, timestamp = {2014-07-19T19:28:16.000+0200}, title = {Neurosensory outcome and growth at three years in extremely low birthweight infants: follow-up results from the Swedish national prospective study.}, username = {ar0berts}, volume = 87, year = 1998 }