Abstract
DNA hybridisation has been used to power a number of
DNA-based nanostructures constructed out of DNA. Here
some considerations that go into DNA-based motor design
are briefly reviewed. The emphasis will be on the
operation of toeholds, single-stranded sections of DNA
that facilitate the process of strand removal during
certain points in the operation of a DNA-based motor.
Reaction kinetics measurements for toehold mediated
strand exchange are reported. These measurements have
served as a guide for choosing toehold lengths.
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