Abstract
The following study was designed and conducted to investigate the bactericidal
effect of common chemical, extensively used in household and laboratories which is
responsible to contaminate the environment and affect the normal flora of human. The
test shows the excellent bactericidal effect of citric acid and acetic acid with the
significant level was from P < 0.05.Salmonella typhi a causative agent of typhoid fever
also restrain effectively with citric acid and acetic acid.Boric acid,a major active
compound of many pesticides has show little effect on the growth of S.aureus and
E.coli.Hence,a non significant effect of sodium hydroxide,sodium bicarbonate and boric
acid effects observed against all four strain of bacteria.with the comparision of standard
antibiotics,namely,Cefixime and levoflaxacin,it is evaluated that the citric acid and
acetic acid have high efficiency against S.aureus,B. Subtilis, S. typhi, and E. coli then
standard antibiotics.It was concluded that among six commonly used chemical citric
acid and acetic acid are highly effective,cheap,efficient,safe and environmentally
friendly product, therefore, seems to be used in pharmaceutical industries or food
industries by using it a suitable and cost effective antiseptic agent and disinfectant, but
further clinical research necessary
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