MATLAB is widely used technical computing software. MATLAB provides graphical design tools such as Simulink and Dials. This paper deals in designing modulation and demodulation techniques of various analog and digital communication systems like AM, FM, PM, PAM, PWM, PPM, PCM, ASK, FSK, PSK, MSK, QPSK, BPSK, BFSK, DSB-SC, SSB-SC. A graphical user interface provides a familiar environment to work. This environment contains pushbuttons, toggle buttons, lists, menus, text boxes, and so forth, all of which are already familiar to the user, so that he or she can concentrate on using the application rather than on the mechanics involved in doing things. Many MATLAB products, such as Curve Fitting Toolbox, Signal Processing Toolbox and Control System Toolbox include apps with custom user interfaces. However, GUIs are harder for the programmer because a GUI-based program must be prepared for mouse clicks (or possibly keyboard input) for any GUI element at any time. Such inputs are known as events, and a program that responds to events is said to be event driven. A graphical User interface (GUI) is a system of graphical elements that allow a user to interact with software using mouse application. GUI can also display data in tabular form or as plots, and can group related components. The graphical user interface (GUI), is a type of user interface that allows users to interact with electronic devices through graphical icons and visual indicators such as secondary notation, instead of text-based user interfaces, typed command labels or text navigation. Mohit Sharma | Subham Sharma | Gaurav Sahu"Designing MATLAB GUI for various Analog and Digital Communication Systems" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-1 , December 2017, URL: http://www.ijtsrd.com/papers/ijtsrd8269.pdf http://www.ijtsrd.com/engineering/electronics-and-communication-engineering/8269/designing-matlab-gui-for-various-analog-and--digital-communication-systems/mohit-sharma