%0 Journal Article %1 Nehe_1998_345 %A Neher, E. %D 1998 %J Cell Calcium %K 10091004 Adenosine Animals, Botulinum Calcium Calcium, Cattle, Cells, Chromaffin Diffusion, Drug Exocytosis, Gov't, Kinetics, Linear Membrane Models, Molecular, Nerve Non-U.S. Proteins, Research Resistance, Signaling, Support, Tetanus Tissue Toxin, Toxins, Triphosphate, %N 5-6 %P 345--357 %T Usefulness and limitations of linear approximations to the understanding of Ca++ signals. %V 24 %X Simple approximations to some limiting cases of Ca++ signalling provide insight into the complex problems of buffered diffusion and of Ca++ homeostasis in the presence of buffers. Three cases are presented, where the influence of Ca++ buffers can readily be understood in the limit of small signals: the return of global cellular Ca++ following a short stimulus in a 'Single Compartment', buffered diffusion along a cylindrical axon in the 'Rapid Buffer Approximation', and nonequilibrium microdomains of elevated Ca++ in the immediate vicinity of open Ca++ channels.

@article{Nehe_1998_345, abstract = {Simple approximations to some limiting cases of Ca++ signalling provide insight into the complex problems of buffered diffusion and of Ca++ homeostasis in the presence of buffers. Three cases are presented, where the influence of Ca++ buffers can readily be understood in the limit of small signals: the return of global cellular [Ca++] following a short stimulus in a 'Single Compartment', buffered diffusion along a cylindrical axon in the 'Rapid Buffer Approximation', and nonequilibrium microdomains of elevated [Ca++] in the immediate vicinity of open Ca++ channels.}, added-at = {2009-06-03T11:20:58.000+0200}, author = {Neher, E.}, biburl = {https://www.bibsonomy.org/bibtex/2733bc6fce0922c0d52fe175ab42ef803/hake}, description = {The whole bibliography file I use.}, file = {Nehe_1998_345.pdf:Nehe_1998_345.pdf:PDF}, interhash = {5490d90608ae8458927c253618190e6c}, intrahash = {733bc6fce0922c0d52fe175ab42ef803}, journal = {Cell Calcium}, key = 51, keywords = {10091004 Adenosine Animals, Botulinum Calcium Calcium, Cattle, Cells, Chromaffin Diffusion, Drug Exocytosis, Gov't, Kinetics, Linear Membrane Models, Molecular, Nerve Non-U.S. Proteins, Research Resistance, Signaling, Support, Tetanus Tissue Toxin, Toxins, Triphosphate,}, number = {5-6}, pages = {345--357}, pmid = {10091004}, timestamp = {2009-06-03T11:21:23.000+0200}, title = {Usefulness and limitations of linear approximations to the understanding of Ca++ signals.}, volume = 24, year = 1998 }