%0 Journal Article %1 ISI:000260851400014 %A Shaabani, Ahmad %A Maleki, Ali %A Mofakham, Hamid %A Khavasi, Hamid Reza %C 1155 16TH ST, NW, WASHINGTON, DC 20036 USA %D 2008 %I AMER CHEMICAL SOC %J JOURNAL OF COMBINATORIAL CHEMISTRY %K imported %N 6 %P 883-885 %R 10.1021/cc800099r %T Novel Isocyanide-Based Three-Component One-Pot Synthesis of Cyanophenylamino-acetamide Derivatives %V 10 %X A one-pot multicomponent synthesis of a novel class of cyanophenylamino-acetamides through the conversion of primary amides to the corresponding nitriles, starting from simple and readily available inputs including 2-aminobenzamide, an aldehyde, and an isocyanide in the presence of p-toluenesulfonic acid as a catalyst, in excellent yields at room temperature in ethanol as a green reaction medium is described.

@article{ISI:000260851400014, abstract = {{A one-pot multicomponent synthesis of a novel class of cyanophenylamino-acetamides through the conversion of primary amides to the corresponding nitriles, starting from simple and readily available inputs including 2-aminobenzamide, an aldehyde, and an isocyanide in the presence of p-toluenesulfonic acid as a catalyst, in excellent yields at room temperature in ethanol as a green reaction medium is described.}}, added-at = {2017-05-10T15:29:29.000+0200}, address = {{1155 16TH ST, NW, WASHINGTON, DC 20036 USA}}, affiliation = {{Shaabani, A (Reprint Author), Shahid Beheshti Univ, Dept Chem, POB 19396-4716, Tehran, Iran. Shaabani, Ahmad; Maleki, Ali; Mofakham, Hamid; Khavasi, Hamid Reza, Shahid Beheshti Univ, Dept Chem, Tehran, Iran.}}, author = {Shaabani, Ahmad and Maleki, Ali and Mofakham, Hamid and Khavasi, Hamid Reza}, author-email = {{a-shaabani@cc.sbu.ac.ir}}, biburl = {https://www.bibsonomy.org/bibtex/2043da8235d36c391851a60b0bc151368/hkhavasi}, cited-references = {{ABDELWAHAB AHF, 2002, ACTA PHARM, V54, P269. Armstrong RW, 1996, ACCOUNTS CHEM RES, V29, P123, DOI 10.1021/ar9502083. Domling A, 2006, CHEM REV, V106, P17, DOI 10.1021/cr0505728. Domling A, 2000, ANGEW CHEM INT EDIT, V39, P3168, DOI 10.1002/1521-3773(20000915)39:18<3168::AID-ANIE3168>3.0.CO;2-U. ERIAN AW, 1993, CHEM REV, V93, P1991, DOI 10.1021/cr00022a002. Krynitsky J.A., 1963, ORG SYNTH, VIV, P436. Kuo CW, 2007, CHEM COMMUN, P301, DOI 10.1036/b614061k. Lahue BR, 2004, J ORG CHEM, V69, P7171, DOI 10.1021/jo040193z. Mander LN, 2003, J AM CHEM SOC, V125, P2400, DOI 10.1021/ja029725o. Mizuno T, 2004, TETRAHEDRON LETT, V45, P7073, DOI 10.1016/j.tetlet.2004.07.152. Reisner D.B., 1963, ORG SYNTH, VIV, P144. Rosowsky A, 2001, J ORG CHEM, V66, P7522, DOI 10.1021/jo010536i. Ruck RT, 2004, ANGEW CHEM INT EDIT, V43, P5375, DOI 10.1002/anie.200461064. Sandler SR, 1983, ORGANIC FUNCTIONAL G. Shaabani A, 2006, TETRAHEDRON LETT, V47, P3031, DOI 10.1016/j.tetlet.2006.03.011. SHAABANI A, 2008, SYNLETT, P323. Shaabani A, 2008, J COMB CHEM, V10, P595, DOI 10.1021/cc8000635. Shaabani A, 2008, J ORG CHEM, V73, P3925, DOI 10.1021/jo8002612. Shaabani A, 2007, J ORG CHEM, V72, P6309, DOI 10.1021/jo0707131. Taylor E.C., 1970, CHEM CYCLIC ENAMINON. Zhu J, 2005, MULTICOMPONENT REACTIONS, P1, DOI 10.1002/3527605118.}}, doc-delivery-number = {{371SK}}, doi = {{10.1021/cc800099r}}, funding-acknowledgement = {{Research Council of Shahid Beheshti University}}, funding-text = {{We gratefully acknowledge financial support from the Research Council of Shahid Beheshti University.}}, interhash = {599adc22c93ceefac195c4099712145c}, intrahash = {043da8235d36c391851a60b0bc151368}, issn = {{1520-4766}}, journal = {{JOURNAL OF COMBINATORIAL CHEMISTRY}}, journal-iso = {{J. Comb. Chem.}}, keywords = {imported}, keywords-plus = {{CHEMISTRY; NITRILES; AMIDES}}, language = {{English}}, month = {{NOV-DEC}}, number = {{6}}, number-of-cited-references = {{21}}, orcid-numbers = {{Maleki, Ali/0000-0001-5490-3350}}, pages = {{883-885}}, publisher = {{AMER CHEMICAL SOC}}, research-areas = {{Chemistry; Pharmacology \& Pharmacy}}, times-cited = {{20}}, timestamp = {2017-05-10T15:29:29.000+0200}, title = {{Novel Isocyanide-Based Three-Component One-Pot Synthesis of Cyanophenylamino-acetamide Derivatives}}, type = {{Article}}, unique-id = {{ISI:000260851400014}}, usage-count-last-180-days = {{0}}, usage-count-since-2013 = {{1}}, volume = {{10}}, web-of-science-categories = {{Chemistry, Applied; Chemistry, Medicinal; Chemistry, Multidisciplinary}}, year = {{2008}} }