%0 Journal Article %1 knapp_serological_1984 %A Knapp, J S %A Tam, M R %A Nowinski, R C %A Holmes, K K %A Sandström, E G %D 1984 %J The Journal of Infectious Diseases %K Antibodies, Arginine, Bacterial Membrane Monoclonal, Neisseria Outer Proline, Proteins, Serotyping, Terminology Topic as gonorrhoeae, %N 1 %P 44--48 %T Serological classification of Neisseria gonorrhoeae with use of monoclonal antibodies to gonococcal outer membrane protein I %U http://www.ncbi.nlm.nih.gov/pubmed/6431013 %V 150 %X Identification of strain-specific markers on Neisseria gonorrhoeae that are capable of differentiating gonococci into a large number of distinct classes could facilitate analysis of patterns of gonorrhea transmission and application of gonorrhea control measures. A panel of 12 monoclonal antibodies to gonococcal outer membrane protein IA (PrIA) and IB (PrIB) was used to classify 1,433 strains serologically in a worldwide survey. Eighteen PrIA and 28 PrIB serovars were identified, and a nomenclature is proposed. Gonococcal strains were classified further by auxotyping. Auxotyping and serotyping served to classify the 1,433 isolates into 107 unique auxotype/serovar classes. Dual classification by auxotype and serovar can be used to identify epidemiologically related gonococcal infections in order to test the effectiveness of innovative, focused measures to control gonorrhea.

@article{knapp_serological_1984, abstract = {Identification of strain-specific markers on Neisseria gonorrhoeae that are capable of differentiating gonococci into a large number of distinct classes could facilitate analysis of patterns of gonorrhea transmission and application of gonorrhea control measures. A panel of 12 monoclonal antibodies to gonococcal outer membrane protein {IA} {(PrIA)} and {IB} {(PrIB)} was used to classify 1,433 strains serologically in a worldwide survey. Eighteen {PrIA} and 28 {PrIB} serovars were identified, and a nomenclature is proposed. Gonococcal strains were classified further by auxotyping. Auxotyping and serotyping served to classify the 1,433 isolates into 107 unique auxotype/serovar classes. Dual classification by auxotype and serovar can be used to identify epidemiologically related gonococcal infections in order to test the effectiveness of innovative, focused measures to control gonorrhea.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {Knapp, J S and Tam, M R and Nowinski, R C and Holmes, K K and Sandström, E G}, biburl = {https://www.bibsonomy.org/bibtex/22b5550cfc6c38c51d1379be3f8b3fed1/jelias}, interhash = {74613c4dc7b6e182d8ee1133b4db0b38}, intrahash = {2b5550cfc6c38c51d1379be3f8b3fed1}, issn = {0022-1899}, journal = {The Journal of Infectious Diseases}, keywords = {Antibodies, Arginine, Bacterial Membrane Monoclonal, Neisseria Outer Proline, Proteins, Serotyping, Terminology Topic as gonorrhoeae,}, month = jul, note = {{PMID:} 6431013}, number = 1, pages = {44--48}, timestamp = {2011-03-11T10:05:38.000+0100}, title = {Serological classification of Neisseria gonorrhoeae with use of monoclonal antibodies to gonococcal outer membrane protein I}, url = {http://www.ncbi.nlm.nih.gov/pubmed/6431013}, volume = 150, year = 1984 }