%0 Journal Article %1 valenza_prevalence_2008 %A Valenza, Giuseppe %A Tappe, Dennis %A Turnwald, Doris %A Frosch, Matthias %A König, Corinne %A Hebestreit, Helge %A Abele-Horn, Marianne %D 2008 %J Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society %K Adolescent, Adult, Bacteria, Bacterial Bacterial, Child, Cystic Disease Drug Female, Fibrosis, Germany, Humans, Infections, Male, Prevalence, Prognosis, Resistance, Retrospective Sputum Studies, Susceptibility, ag_horn {Follow-Up} %N 2 %P 123--127 %R 10.1016/j.jcf.2007.06.006 %T Prevalence and antimicrobial susceptibility of microorganisms isolated from sputa of patients with cystic fibrosis %U http://www.ncbi.nlm.nih.gov/pubmed/17693140 %V 7 %X \textlessAbstractText Label="BACKGROUND" NlmCategory="BACKGROUND"\textgreaterNew emerging pathogens and associated antimicrobial resistance mechanisms have been observed in the respiratory tract of patients suffering from cystic fibrosis (CF) in the last years. Amongst others, the rate of metallo-beta-lactamase (MBL)-producing Pseudomonas aeruginosa strains is growing. However, there are no published data on the prevalence of MBL-producing P. aeruginosa in CF patients to our knowledge.\textless/AbstractText\textgreater \textlessAbstractText Label="METHODS" NlmCategory="METHODS"\textgreaterIn this study, 271 sputum samples of 60 CF patients were collected during a 12-months period. Microbiological cultures and antimicrobial susceptibility tests of the most frequently isolated bacteria were performed.\textless/AbstractText\textgreater \textlessAbstractText Label="RESULTS" NlmCategory="RESULTS"\textgreater464 bacterial and 414 fungal strains were isolated and characterized. 63.3\% of the patients harbored Staphylococcus aureus, 50\% P. aeruginosa, 16.6\% Haemophilus influenzae, 15\% Stenotrophomonas maltophilia and 13.3\% non tuberculous Mycobacteria (NTM). Methicillin resistant S. aureus (MRSA) and MBL-producing P. aeruginosa were detected in 3 (5\%) and 5 (8.3\%) patients respectively. Among the fungi, Aspergillus fumigatus and Candida albicans showed the highest prevalence.\textless/AbstractText\textgreater \textlessAbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS"\textgreaterThe detection of MBL-producing P. aeruginosa and MRSA in CF patients confirms that antimicrobial resistance patterns should be always kept under surveillance. Moreover hygiene regulations in CF clinics should prevent a further spread of resistant bacterial strains.\textless/AbstractText\textgreater

@article{valenza_prevalence_2008, abstract = {{{\textless}AbstractText} {Label="BACKGROUND"} {NlmCategory="BACKGROUND"{\textgreater}New} emerging pathogens and associated antimicrobial resistance mechanisms have been observed in the respiratory tract of patients suffering from cystic fibrosis {(CF)} in the last years. Amongst others, the rate of metallo-beta-lactamase {(MBL)-producing} Pseudomonas aeruginosa strains is growing. However, there are no published data on the prevalence of {MBL-producing} P. aeruginosa in {CF} patients to our {knowledge.{\textless}/AbstractText{\textgreater}} {{\textless}AbstractText} {Label="METHODS"} {NlmCategory="METHODS"{\textgreater}In} this study, 271 sputum samples of 60 {CF} patients were collected during a 12-months period. Microbiological cultures and antimicrobial susceptibility tests of the most frequently isolated bacteria were {performed.{\textless}/AbstractText{\textgreater}} {{\textless}AbstractText} {Label="RESULTS"} {NlmCategory="RESULTS"{\textgreater}464} bacterial and 414 fungal strains were isolated and characterized. 63.3\% of the patients harbored Staphylococcus aureus, 50\% P. aeruginosa, 16.6\% Haemophilus influenzae, 15\% Stenotrophomonas maltophilia and 13.3\% non tuberculous Mycobacteria {(NTM).} Methicillin resistant S. aureus {(MRSA)} and {MBL-producing} P. aeruginosa were detected in 3 (5\%) and 5 (8.3\%) patients respectively. Among the fungi, Aspergillus fumigatus and Candida albicans showed the highest {prevalence.{\textless}/AbstractText{\textgreater}} {{\textless}AbstractText} {Label="CONCLUSIONS"} {NlmCategory="CONCLUSIONS"{\textgreater}The} detection of {MBL-producing} P. aeruginosa and {MRSA} in {CF} patients confirms that antimicrobial resistance patterns should be always kept under surveillance. Moreover hygiene regulations in {CF} clinics should prevent a further spread of resistant bacterial {strains.{\textless}/AbstractText{\textgreater}}}, added-at = {2011-04-07T15:44:20.000+0200}, author = {Valenza, Giuseppe and Tappe, Dennis and Turnwald, Doris and Frosch, Matthias and König, Corinne and Hebestreit, Helge and {Abele-Horn}, Marianne}, biburl = {https://www.bibsonomy.org/bibtex/255a1a1f4b2ed97281f50702778ecb80d/hymi}, doi = {10.1016/j.jcf.2007.06.006}, interhash = {761c47bc31020e3b222f5689514656d4}, intrahash = {55a1a1f4b2ed97281f50702778ecb80d}, issn = {1569-1993}, journal = {Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society}, keywords = {Adolescent, Adult, Bacteria, Bacterial Bacterial, Child, Cystic Disease Drug Female, Fibrosis, Germany, Humans, Infections, Male, Prevalence, Prognosis, Resistance, Retrospective Sputum Studies, Susceptibility, ag_horn {Follow-Up}}, month = mar, note = {{PMID:} 17693140}, number = 2, pages = {123--127}, timestamp = {2011-04-07T16:35:56.000+0200}, title = {Prevalence and antimicrobial susceptibility of microorganisms isolated from sputa of patients with cystic fibrosis}, url = {http://www.ncbi.nlm.nih.gov/pubmed/17693140}, volume = 7, year = 2008 }