%0 Journal Article %1 Ferre2009 %A Ferre, S. %A Baler, R. %A Bouvier, M. %A Caron, M. G. %A Devi, L. A. %A Durroux, T. %A Fuxe, K. %A George, S. R. %A Javitch, J. A. %A Lohse, M. J. %A Mackie, K. %A Milligan, G. %A Pfleger, K. D. %A Pin, J. P. %A Volkow, N. D. %A Waldhoer, M. %A Woods, A. S. %A Franco, R. %D 2009 %J Nat Chem Biol %K *Signal Cell Design Drug Surface/*drug Transduction effects/metabolism Receptor %N 3 %P 131-4 %T Building a new conceptual framework for receptor heteromers %U http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19219011 %V 5 %X Receptor heteromers constitute a new area of research that is reshaping our thinking about biochemistry, cell biology, pharmacology and drug discovery. In this commentary, we recommend clear definitions that should facilitate both information exchange and research on this growing class of transmembrane signal transduction units and their complex properties. We also consider research questions underlying the proposed nomenclature, with recommendations for receptor heteromer identification in native tissues and their use as targets for drug development.

@article{Ferre2009, abstract = {Receptor heteromers constitute a new area of research that is reshaping our thinking about biochemistry, cell biology, pharmacology and drug discovery. In this commentary, we recommend clear definitions that should facilitate both information exchange and research on this growing class of transmembrane signal transduction units and their complex properties. We also consider research questions underlying the proposed nomenclature, with recommendations for receptor heteromer identification in native tissues and their use as targets for drug development.}, added-at = {2010-12-14T18:12:02.000+0100}, author = {Ferre, S. and Baler, R. and Bouvier, M. and Caron, M. G. and Devi, L. A. and Durroux, T. and Fuxe, K. and George, S. R. and Javitch, J. A. and Lohse, M. J. and Mackie, K. and Milligan, G. and Pfleger, K. D. and Pin, J. P. and Volkow, N. D. and Waldhoer, M. and Woods, A. S. and Franco, R.}, biburl = {https://www.bibsonomy.org/bibtex/26fd1c41120f80c285a54e9ad25e9c7c5/pharmawuerz}, endnotereftype = {Journal Article}, interhash = {76b664f54258eb2f0327a4f03f5d90c6}, intrahash = {6fd1c41120f80c285a54e9ad25e9c7c5}, issn = {1552-4469 (Electronic)}, journal = {Nat Chem Biol}, keywords = {*Signal Cell Design Drug Surface/*drug Transduction effects/metabolism Receptor}, month = Mar, note = {Ferre, Sergi Baler, Ruben Bouvier, Michel Caron, Marc G Devi, Lakshmi A Durroux, Thierry Fuxe, Kjell George, Susan R Javitch, Jonathan A Lohse, Martin J Mackie, Ken Milligan, Graeme Pfleger, Kevin D G Pin, Jean-Philippe Volkow, Nora D Waldhoer, Maria Woods, Amina S Franco, Rafael Research Support, N.I.H., Extramural United States Nature chemical biology Nat Chem Biol. 2009 Mar;5(3):131-4.}, number = 3, pages = {131-4}, shorttitle = {Building a new conceptual framework for receptor heteromers}, timestamp = {2010-12-14T18:20:02.000+0100}, title = {Building a new conceptual framework for receptor heteromers}, url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19219011}, volume = 5, year = 2009 }