%0 Journal Article %1 umang_haribhai_gajjar_2021_5131622 %A Gajjar, Umang Haribhai %A Velhal, Niralee Kalpeshkumar %A Parikh, Hetvi Girdharbhai %A Parmar, Jayrajsinh Bhartbhai %A Bhut, Yash %A Patel, Viral Rupeshbhai %D 2021 %J World Journal of Biology Pharmacy and Health Sciences %K Datura Seed %N 1 %P 030-035 %R 10.30574/wjbphs.2021.7.1.0070 %T Evaluation of antioxidant activity of unpurified and purified datura seed %U http://wjbphs.com/content/evaluation-antioxidant-activity-unpurified-and-purified-datura-seed %V 7 %X Aim: Evaluation of effect of shodhana process of datura seed (Datura stramonium) antioxidant activity. Methods: The datura was purified with two different processes viz. cow’s urine, and cow’s milk by Dolayantra method. Antioxidant activity was evaluated by in-vitro 1,1-Diphenyl-2-picryl hydrazyl (DPPH) radicals scavenging activity and Ferric reducing power ability (FRPA) assay. Result: cow urine purified datura (CUD) showed a significant effect in inhibiting DPPH, reaching up to 85.96% at concentration 1000 mcg/ml and its IC50 was 314.3 mcg/ml while Unpurified Datura Seed (UD) reaching up to 86.06% at concentration 1000 mcg/ml and its IC50 was 171.73 mcg/ml. The Cow Milk Purified Datura Seed (CMD) extract reach 69.72% at concentration 1000 mcg/ml and its IC50 value was 640. The IC50 value of Ascorbic acid was 23.35 mcg/ml. CUD showed a significant effect in reduction of ferric ion, reaching up to 85.59% reduction at concentration 1000 mcg/ml and its EC50 was 304.46 mcg/ml while UD reaching up to 86.11% at concentration 1000 mcg/ml and its EC50 was 280.28 mcg/ml. CMD extract reach 52.28% at concentration 1000 mcg/ml and its EC50 value was 1091.3mcg/ml.

@article{umang_haribhai_gajjar_2021_5131622, abstract = {Aim: Evaluation of effect of shodhana process of datura seed (Datura stramonium) antioxidant activity. Methods: The datura was purified with two different processes viz. cow’s urine, and cow’s milk by Dolayantra method. Antioxidant activity was evaluated by in-vitro 1,1-Diphenyl-2-picryl hydrazyl (DPPH) radicals scavenging activity and Ferric reducing power ability (FRPA) assay. Result: cow urine purified datura (CUD) showed a significant effect in inhibiting DPPH, reaching up to 85.96% at concentration 1000 mcg/ml and its IC50 was 314.3 mcg/ml while Unpurified Datura Seed (UD) reaching up to 86.06% at concentration 1000 mcg/ml and its IC50 was 171.73 mcg/ml. The Cow Milk Purified Datura Seed (CMD) extract reach 69.72% at concentration 1000 mcg/ml and its IC50 value was 640. The IC50 value of Ascorbic acid was 23.35 mcg/ml. CUD showed a significant effect in reduction of ferric ion, reaching up to 85.59% reduction at concentration 1000 mcg/ml and its EC50 was 304.46 mcg/ml while UD reaching up to 86.11% at concentration 1000 mcg/ml and its EC50 was 280.28 mcg/ml. CMD extract reach 52.28% at concentration 1000 mcg/ml and its EC50 value was 1091.3mcg/ml.}, added-at = {2021-07-24T16:14:24.000+0200}, author = {Gajjar, Umang Haribhai and Velhal, Niralee Kalpeshkumar and Parikh, Hetvi Girdharbhai and Parmar, Jayrajsinh Bhartbhai and Bhut, Yash and Patel, Viral Rupeshbhai}, biburl = {https://www.bibsonomy.org/bibtex/26a6ce2654f7940a33c127cf642ee7ca6/wjbphsjournal}, doi = {10.30574/wjbphs.2021.7.1.0070}, interhash = {78f20b125e4165ea2afd5ae305db6ba8}, intrahash = {6a6ce2654f7940a33c127cf642ee7ca6}, issn = {2582-5542}, journal = {{World Journal of Biology Pharmacy and Health Sciences}}, keywords = {Datura Seed}, month = jul, number = 1, pages = {030-035}, timestamp = {2021-07-24T16:14:24.000+0200}, title = {Evaluation of antioxidant activity of unpurified and purified datura seed}, url = {http://wjbphs.com/content/evaluation-antioxidant-activity-unpurified-and-purified-datura-seed}, volume = 7, year = 2021 }