%0 Journal Article %1 slater00a %A Slater, G. W. %A Desrulsseaux, C. %A Hubert, S. J. %A Mercier, J. F. %A Labrie, J. %A Boileau, J. %A Tessier, F. %A Pepin, M. P. %D 2000 %J Electrophoresis %K AGAROSE CAPILLARY-ELECTROPHORESIS; DNA; ELECTROPHORESIS; END-LABELED GEL-ELECTROPHORESIS; GELS LOW-VISCOSITY MODEL; OGSTON POLYMER-SOLUTIONS; POLYMER; PULSED-FIELD SINGLE-STRANDED-DNA; SOLVABLE TRAPPING ULTRADILUTE experiment, review, theory, %N 18 %P 3873--3887 %T Theory of DNA electrophoresis: A look at some current challenges %V 21 %X Although electrophoresis is one of the basic methods of the modern molecular biology laboratory, new ideas are being suggested at an accelerated rate, in large part because of the pressing demands of the biomedical community. Although we now have, at least for some methods, a fairly good theoretical understanding of the physical mechanisms that lead to the observed peak spacings, widths and shapes, this knowledge is often too qualitative to be used to guide further technical developments and improvements. In this article, we review some selected elements of the current state of our theoretical ignorance, focusing mostly on DNA electrophoresis, and we offer several suggestions for further theoretical investigations.

@article{slater00a, abstract = {Although electrophoresis is one of the basic methods of the modern molecular biology laboratory, new ideas are being suggested at an accelerated rate, in large part because of the pressing demands of the biomedical community. Although we now have, at least for some methods, a fairly good theoretical understanding of the physical mechanisms that lead to the observed peak spacings, widths and shapes, this knowledge is often too qualitative to be used to guide further technical developments and improvements. In this article, we review some selected elements of the current state of our theoretical ignorance, focusing mostly on DNA electrophoresis, and we offer several suggestions for further theoretical investigations.}, added-at = {2007-06-15T17:33:15.000+0200}, author = {Slater, G. W. and Desrulsseaux, C. and Hubert, S. J. and Mercier, J. F. and Labrie, J. and Boileau, J. and Tessier, F. and Pepin, M. P.}, biburl = {https://www.bibsonomy.org/bibtex/20649bd7b2ed120342a4698f20bbd7d05/kaigrass}, comment = {outstanding}, interhash = {78f552ff1277b834dab98fcc68c3fe2f}, intrahash = {0649bd7b2ed120342a4698f20bbd7d05}, journal = {Electrophoresis}, keywords = {AGAROSE CAPILLARY-ELECTROPHORESIS; DNA; ELECTROPHORESIS; END-LABELED GEL-ELECTROPHORESIS; GELS LOW-VISCOSITY MODEL; OGSTON POLYMER-SOLUTIONS; POLYMER; PULSED-FIELD SINGLE-STRANDED-DNA; SOLVABLE TRAPPING ULTRADILUTE experiment, review, theory,}, month = {December}, number = 18, owner = {grass}, pages = {3873--3887}, pdf = {slater00a.pdf}, timestamp = {2007-06-15T17:33:23.000+0200}, title = {Theory of {DNA} electrophoresis: {A} look at some current challenges}, volume = 21, year = 2000 }