Article,

A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection

, and .
Cell, (2020)
DOI: https://doi.org/10.1016/j.cell.2020.05.016

Abstract

SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers – individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease – presents a unique opportunity to reveal human genetic determinants of infection and disease.

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