Article,

Microbiology: Altruistic defence

, and .
Nature, 467 (7311): 34--35 (Sep 2, 2010)
DOI: 10.1038/467034a

Abstract

A charitable deed by a few cells in a bacterial culture can help the rest of that population survive in the presence of antibiotics. This finding can aid further research into a major problem in public health. Bacterial resistance to an antibiotic arises when mutations in the DNA of a few cells in a bacterial population enable them to fend off the harmful effects of the antibiotic. This gives such cells a selective growth advantage through, for example, being able to pump out the antibiotic faster than it can kill them.

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