%0 Journal Article %1 Turnbull2017 %A Turnbull, Bruce W %D 2017 %J Clinical trials (London, England) %K Adaptivedesign enrichmentdesign flexibledesign group-sequentialtest multi-armmulti-stagetrial optimaldesign promisingzone samplesizere-estimation seamlessPhaseII/IIIdesign %N 5 %P 462-469 %R 10.1177/1740774516689261 %T Adaptive designs from a Data Safety Monitoring Board perspective: Some controversies and some case studies. %U http://journals.sagepub.com/doi/10.1177/1740774516689261 http://www.ncbi.nlm.nih.gov/pubmed/28178849 %V 14 %X This article describes vignettes concerning interactions with Data Safety Monitoring Boards during the design and monitoring of some clinical trials with an adaptive design. Most reflect personal experiences by the author.

@article{Turnbull2017, abstract = {This article describes vignettes concerning interactions with Data Safety Monitoring Boards during the design and monitoring of some clinical trials with an adaptive design. Most reflect personal experiences by the author.}, added-at = {2023-02-03T11:44:35.000+0100}, author = {Turnbull, Bruce W}, biburl = {https://www.bibsonomy.org/bibtex/2289d3af41bf092f9226a995b151fbc84/jepcastel}, doi = {10.1177/1740774516689261}, interhash = {868d2f041b4e0c0e3853aef4b0118bfe}, intrahash = {289d3af41bf092f9226a995b151fbc84}, issn = {1740-7753}, journal = {Clinical trials (London, England)}, keywords = {Adaptivedesign enrichmentdesign flexibledesign group-sequentialtest multi-armmulti-stagetrial optimaldesign promisingzone samplesizere-estimation seamlessPhaseII/IIIdesign}, month = {10}, note = {Disseny; Dissenys adaptatius}, number = 5, pages = {462-469}, pmid = {28178849}, timestamp = {2023-02-03T11:44:35.000+0100}, title = {Adaptive designs from a Data Safety Monitoring Board perspective: Some controversies and some case studies.}, url = {http://journals.sagepub.com/doi/10.1177/1740774516689261 http://www.ncbi.nlm.nih.gov/pubmed/28178849}, volume = 14, year = 2017 }