Abstract
In three-stage prospective cohort controlled research of 2876 persons with chronic diffuse liver diseases
(2076 cases of fatty liver disease, 509 cases of chronic hepatitis, 139 cases of liver cirrhosis) and 152
healthy controls the clinical significance of radiation methods of investigation in quantitative evaluation of
liver morphofunctional state in patients with chronic diffuse liver diseases was estimated. Diagnosisprognostic algorithm for patients with this pathology was developed, validated and recommended for
practical application. Further perspectives are related to detailed chronic diffuse liver diseases
stratification by intensity of steatosis (in fatty liver disease), activity (in chronic hepatitis) and fibrosis (in
chronic hepatitis and liver cirrhosis).
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