Article,

The effects of cisapride on gastro-oesophageal reflux in children with and without neurological disorders.

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Dev Med Child Neurol, 32 (7): 629--632 (July 1990)

Abstract

Cisapride was used to treat gastro-oesophageal reflux in seven children with neurodevelopmental disorders and in 15 children who were neurologically normal. 24-hour lower-oesophageal pH monitoring was carried out before and after treatment. The neurologically normal group had a statistically significant decrease after treatment in percentage time pH less than 4, but children with neurological abnormalities did not have a comparable improvement in reflux scores.

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