Abstract
We studied both experimentally and numerically on the formation of water channel network connecting macroscopic cavities in a granular material. The collapse and merging of the cavities occur as a result of the local concentration of viscous flow into (and the enhancement of the stress at the macroscopic boundary of) the cavities, which changes the global flow, and vice verse. Similar processes are expected in human liver, where new blood vessels into rapidly growing tumor cells are created. We use these network channels to achieve effective transport of nanoscale liposomes containing drugs.
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