%0 Journal Article %1 smith2020halting %A Smith, Kira %D 2020 %I Openventio Publishers %J Epidemiology Open Journal %K %N 1 %P 13-15 %R 10.17140/EPOJ-5-119 %T Halting Coronavirus Replication %U https://openventio.org/wp-content/uploads/Halting-Coronavirus-Replication-EPOJ-5-119.pdf %V 5 %X Sirtuin 1 (SIRT1) inhibitors can reduce replication of many viruses with certain characteristics similar to those of coronaviruses, while the p53 protein is another important factor in the down-regulation of viral growth. Tenovin is a class of small molecules that inhibit Sirtuin 1 and 2, in addition to activating the p53 protein, by means of regulating the interactions used by coronaviruses as a self-defense mechanism. By blocking virus growth and continuous replication, with already tested antiviral medicines, the promise of coronavirus disease 2019 (COVID-19) eradication exists.

@article{smith2020halting, abstract = {Sirtuin 1 (SIRT1) inhibitors can reduce replication of many viruses with certain characteristics similar to those of coronaviruses, while the p53 protein is another important factor in the down-regulation of viral growth. Tenovin is a class of small molecules that inhibit Sirtuin 1 and 2, in addition to activating the p53 protein, by means of regulating the interactions used by coronaviruses as a self-defense mechanism. By blocking virus growth and continuous replication, with already tested antiviral medicines, the promise of coronavirus disease 2019 (COVID-19) eradication exists.}, added-at = {2021-03-31T22:07:06.000+0200}, author = {Smith, Kira}, biburl = {https://www.bibsonomy.org/bibtex/2cc790c23227aa876cf5643d158580cc5/kill4thethrill}, day = 05, doi = {10.17140/EPOJ-5-119}, interhash = {c4d77cbbe6408f8739aceedfbabb2e30}, intrahash = {cc790c23227aa876cf5643d158580cc5}, issn = {2473-4780}, journal = {Epidemiology Open Journal}, keywords = {}, language = {English}, month = {10}, number = 1, pages = {13-15}, publisher = {Openventio Publishers}, timestamp = {2021-03-31T22:07:06.000+0200}, title = {Halting Coronavirus Replication}, url = {https://openventio.org/wp-content/uploads/Halting-Coronavirus-Replication-EPOJ-5-119.pdf}, volume = 5, year = 2020 }