Tracking the evolution of thermostability in resurrected ancestors of a heat-tolerant extremophile protein and its less heat tolerant Escherichia coli homologue shows how thermostability has probably explored different mechanisms of protein stabilization over evolutionary time.
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%0 Journal Article
%1 hart2014thermodynamic
%A Hart, Kathryn M.
%A Harms, Michael J.
%A Schmidt, Bryan H.
%A Elya, Carolyn
%A Thornton, Joseph W.
%A Marqusee, Susan
%D 2014
%I Public Library of Science
%J PLOS Biology
%K ancestral_reconstruction molecular_evolution phylogenetics ribonuclease systems_drift thermodynamic_model
%N 11
%P 1-12
%R 10.1371/journal.pbio.1001994
%T Thermodynamic System Drift in Protein Evolution
%U https://doi.org/10.1371/journal.pbio.1001994
%V 12
%X Tracking the evolution of thermostability in resurrected ancestors of a heat-tolerant extremophile protein and its less heat tolerant Escherichia coli homologue shows how thermostability has probably explored different mechanisms of protein stabilization over evolutionary time.
@article{hart2014thermodynamic,
abstract = {Tracking the evolution of thermostability in resurrected ancestors of a heat-tolerant extremophile protein and its less heat tolerant Escherichia coli homologue shows how thermostability has probably explored different mechanisms of protein stabilization over evolutionary time.},
added-at = {2017-10-24T00:18:57.000+0200},
author = {Hart, Kathryn M. and Harms, Michael J. and Schmidt, Bryan H. and Elya, Carolyn and Thornton, Joseph W. and Marqusee, Susan},
biburl = {https://www.bibsonomy.org/bibtex/21f7bc90ab2aec04c920eaa0c74a301a3/peter.ralph},
doi = {10.1371/journal.pbio.1001994},
interhash = {e0b66105077cd9564261735fc5525393},
intrahash = {1f7bc90ab2aec04c920eaa0c74a301a3},
journal = {PLOS Biology},
keywords = {ancestral_reconstruction molecular_evolution phylogenetics ribonuclease systems_drift thermodynamic_model},
month = {11},
number = 11,
pages = {1-12},
publisher = {Public Library of Science},
timestamp = {2017-10-24T00:18:57.000+0200},
title = {Thermodynamic System Drift in Protein Evolution},
url = {https://doi.org/10.1371/journal.pbio.1001994},
volume = 12,
year = 2014
}