Article,

Flow injection immunoanalysis based on a magnetoimmunosensor system.

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Analytical Chemistry, 70 (8): 1462--1467 (April 1998)
DOI: 10.1021/ac970441+ S0003-2700(97)00441-1

Abstract

A new immunosensor integrated to a flow system has been developed. It is based on magnetic immunoparticles immobilized on a solid-state transducer using a magnetic field. The described technique renews the immunoparticles reproducibly for each analysis allowing a good measurement precision. The developed experimental approach permits the implementation of an automated immunoassay that is quick (analytical cycle < 30 min) and sensitive in the micromolar concentration range. The system was applied to the determination of rabbit immunoglobulin G as an analyte model.

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