%0 Journal Article %1 Connor2008 %A Connor, Jason T %D 2008 %J The American journal of gastroenterology %K BiomedicalResearch ClinicalTrialsasTopic ClinicalTrialsasTopic:statistics&numericald CrohnDisease CrohnDisease:drugtherapy DataInterpretation Humans ImmunosuppressiveAgents ImmunosuppressiveAgents:therapeuticuse PublicationBias Publishing Publishing:ethics Sirolimus Sirolimus:analogs&derivatives Sirolimus:therapeuticuse Statistical TreatmentFailure %N 9 %P 2181-3 %R 10.1111/j.1572-0241.2008.02028.x %T Positive reasons for publishing negative findings. %U http://www.ncbi.nlm.nih.gov/pubmed/18671812 %V 103 %X Scientific and medical authors tend to be biased toward submitting "statistically significant" findings for publication. Journals show a similar bias in publishing such "positive" studies. The large number of publications in medical research means that, in a field obsessed with controlling Type I error rates, we have journals with an abundance of Type I errors. Failing to publish studies that do not show a treatment or exposure effect creates a literature conspicuously absent of trials necessary for unbiased meta-analyses and systematic reviews. Furthermore, by shelving or rejecting studies with nonstatistically significant outcomes, authors and editors censor the most important contributors to medical research: our consenting volunteers. %@ 1572-0241

@article{Connor2008, abstract = {Scientific and medical authors tend to be biased toward submitting "statistically significant" findings for publication. Journals show a similar bias in publishing such "positive" studies. The large number of publications in medical research means that, in a field obsessed with controlling Type I error rates, we have journals with an abundance of Type I errors. Failing to publish studies that do not show a treatment or exposure effect creates a literature conspicuously absent of trials necessary for unbiased meta-analyses and systematic reviews. Furthermore, by shelving or rejecting studies with nonstatistically significant outcomes, authors and editors censor the most important contributors to medical research: our consenting volunteers.}, added-at = {2023-02-03T11:44:35.000+0100}, author = {Connor, Jason T}, biburl = {https://www.bibsonomy.org/bibtex/270f8d20b0fc27a48fab8f6e47c99ebe9/jepcastel}, city = {Berry Consultants, Orlando, Florida 32835, USA.}, doi = {10.1111/j.1572-0241.2008.02028.x}, interhash = {eed6af9716a5a36531750a6b97e250ef}, intrahash = {70f8d20b0fc27a48fab8f6e47c99ebe9}, isbn = {1572-0241}, issn = {1572-0241}, journal = {The American journal of gastroenterology}, keywords = {BiomedicalResearch ClinicalTrialsasTopic ClinicalTrialsasTopic:statistics&numericald CrohnDisease CrohnDisease:drugtherapy DataInterpretation Humans ImmunosuppressiveAgents ImmunosuppressiveAgents:therapeuticuse PublicationBias Publishing Publishing:ethics Sirolimus Sirolimus:analogs&derivatives Sirolimus:therapeuticuse Statistical TreatmentFailure}, month = {9}, note = {4643<m:linebreak></m:linebreak>JID: 0421030; 0 (Immunosuppressive Agents); 159351-69-6 (everolimus); 53123-88-9 (Sirolimus); CON: Am J Gastroenterol. 2008 Sep;103(9):2284-92. PMID: 18671816; 2008/07/30 [aheadofprint]; ppublish;<m:linebreak></m:linebreak>Publicació}, number = 9, pages = {2181-3}, pmid = {18671812}, timestamp = {2023-02-03T11:44:35.000+0100}, title = {Positive reasons for publishing negative findings.}, url = {http://www.ncbi.nlm.nih.gov/pubmed/18671812}, volume = 103, year = 2008 }