%0 Conference Paper %1 WOS:000287727800301 %A Mendes, Jocelia S %A Silva, Jouciane S %A Ferreira, Andrea L O %A Silva, Giovanilton F %B 10TH INTERNATIONAL SYMPOSIUM ON PROCESS SYSTEMS ENGINEERING %C SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS %D 2009 %E Biscaia, RM deBritoAlves and CAO doNascimento and EC %I ELSEVIER SCIENCE BV %K Candida antarctica; bed bioreactor} fluidized from interesterification; lipase {biodiesel; %P 1803-1808 %T Simulation of Process Interesterification in Fluidized Bed Bioreactor for Production of Biodiesel %V 27 %X The aim this work was investigated a new route for biodiesel production using immobilized lipase from Candida antarctica in continuous Fluidized Bed Bioreactor. Conventionally, Biodiesel (fatty acid methyl esters) is produced by transesterification in which, oil or fat is reacted with a monohydric alcohol in presence of a catalyst. In recent years, the use of lipases as biocatalysts for biodiesel production has become of great interest due to its environment friendly. But some alcohols such as methanol inactivated the lipases to some extent and the enzymatic stability was poor. In order to enhance the stability of the lipase, three-step methanolysis was adopted, however, glycerol, as one of the products was easy to adsorb on the surface of lipase resulting in serious negative effect on the enzymatic activity. For to solve problems was used the interesterification kinetics of triglycerides and methyl acetate for biodiesel production was modeled. A heterogeneous model describing the interesterification process in an immobilized enzyme fluidized-bed bioreactor was developed. A simplified model based on Ping Pong Bi Bi with substrate competitive inhibition mechanism was proposed to describe the reaction kinetics of the interesterification. The model without any adjustable parameters was used to predict the interesterification process. The key parameters which measured the extent of external and internal mass-transport resistances, as well as the degree of back-mixing were quantified and discussed. The fluidized-bed bioreactor considered in this investigation is composed of two phases: a fluid phase comprised mainly of the triglycerides and methyl acetate and the product (Biodiesel); and a solid phase which is the immobilized enzyme. The effects of some operating and design parameters on the performance of the fluidized-bed bioreactor were also analyzed. The model was also tested for its sensitivity to changes in hydrodynamic parameters.

@inproceedings{WOS:000287727800301, abstract = {The aim this work was investigated a new route for biodiesel production using immobilized lipase from Candida antarctica in continuous Fluidized Bed Bioreactor. Conventionally, Biodiesel (fatty acid methyl esters) is produced by transesterification in which, oil or fat is reacted with a monohydric alcohol in presence of a catalyst. In recent years, the use of lipases as biocatalysts for biodiesel production has become of great interest due to its environment friendly. But some alcohols such as methanol inactivated the lipases to some extent and the enzymatic stability was poor. In order to enhance the stability of the lipase, three-step methanolysis was adopted, however, glycerol, as one of the products was easy to adsorb on the surface of lipase resulting in serious negative effect on the enzymatic activity. For to solve problems was used the interesterification kinetics of triglycerides and methyl acetate for biodiesel production was modeled. A heterogeneous model describing the interesterification process in an immobilized enzyme fluidized-bed bioreactor was developed. A simplified model based on Ping Pong Bi Bi with substrate competitive inhibition mechanism was proposed to describe the reaction kinetics of the interesterification. The model without any adjustable parameters was used to predict the interesterification process. The key parameters which measured the extent of external and internal mass-transport resistances, as well as the degree of back-mixing were quantified and discussed. The fluidized-bed bioreactor considered in this investigation is composed of two phases: a fluid phase comprised mainly of the triglycerides and methyl acetate and the product (Biodiesel); and a solid phase which is the immobilized enzyme. The effects of some operating and design parameters on the performance of the fluidized-bed bioreactor were also analyzed. The model was also tested for its sensitivity to changes in hydrodynamic parameters.}, added-at = {2022-05-23T20:00:14.000+0200}, address = {SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS}, author = {Mendes, Jocelia S and Silva, Jouciane S and Ferreira, Andrea L O and Silva, Giovanilton F}, biburl = {https://www.bibsonomy.org/bibtex/2eb484008935e15e1a152bb0c14b8a922/ppgfis_ufc_br}, booktitle = {10TH INTERNATIONAL SYMPOSIUM ON PROCESS SYSTEMS ENGINEERING}, editor = {Biscaia, RM {deBritoAlves and CAO doNascimento and EC}}, interhash = {f122d777593f21bf9276970484bbbf81}, intrahash = {eb484008935e15e1a152bb0c14b8a922}, issn = {1570-7946}, keywords = {Candida antarctica; bed bioreactor} fluidized from interesterification; lipase {biodiesel;}, note = {10th International Symposium on Process Systems Engineering, Salvador, BRAZIL, AUG 16-20, 2009}, pages = {1803-1808}, publisher = {ELSEVIER SCIENCE BV}, pubstate = {published}, series = {Computer-Aided Chemical Engineering}, timestamp = {2022-05-23T20:00:14.000+0200}, title = {Simulation of Process Interesterification in Fluidized Bed Bioreactor for Production of Biodiesel}, tppubtype = {inproceedings}, volume = 27, year = 2009 }