Article,

Cerebral MRI findings in very-low-birth-weight and small-for-gestational-age children at 15 years of age.

, , , , , , and .
Pediatr Radiol, 35 (8): 758--765 (August 2005)
DOI: 10.1007/s00247-005-1446-2

Abstract

BACKGROUND: A high prevalence of abnormal cerebral MRI findings has been reported in low-birth-weight children. OBJECTIVE: To compare MRI findings in very-low-birth-weight (VLBW) and term small-for-gestational-age (SGA) children with controls in early adolescence. MATERIALS AND METHODS: Cerebral MRI was used to examine 55 VLBW, 54 SGA and 66 controls at 15 years of age. The MR images were qualitatively assessed, and size of ventricles, white-matter and grey-matter abnormalities were reported. RESULTS: The VLBW teenagers had a higher prevalence of various MRI abnormalities than SGA children and controls. Dilation of the ventricular system, especially of the occipital horns, was found in 82\% of the VLBW group, in 19\% of the SGA group and in 21\% of controls. White-matter reduction was found in 53\% of the VLBW, in 6\% of the SGA and in 2\% of controls. Corpus callosum thinning was found in 47\% of the VLBW, in 2\% of the SGA and in 6\% of controls. Periventricular gliosis was found in 29\% of the VLBW, in 4\% of the SGA and in 8\% of controls. CONCLUSIONS: Cerebral MRI pathology in white matter is a common finding in VLBW teenagers. The findings may indicate minor perinatal PVL with resulting loss of white-matter tissue and ventricular dilation.

Tags

Users

  • @ar0berts

Comments and Reviews