tag :: Adrenergic sarcoplasmic

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2Ca2+ cycling and new therapeutic approaches for heart failure
A. Lompre, R. Hajjar, S. Harding, E. Kranias, M. Lohse, and A. Marks. Circulation, 121 (6): 822-30 (February 2010)Lompre, Anne-Marie Hajjar, Roger J Harding, Sian E Kranias, Evangelia G Lohse, Martin J Marks, Andrew R United States Circulation Circulation. 2010 Feb 16;121(6):822-30. Epub 2010 Feb 1..
14 years ago by @pharmawuerz
show all tags
ATPases/metabolism
Animal
Animals
Calcium-Transporting
Calcium/*metabolism
Disease
Failure/*drug
Heart
Humans
Mice
Models,
Reticulum
Reticulum/metabolism
Sarcoplasmic
Signal
Transduction
beta/metabolism
therapy/*metabolism
Receptor
Adrenergic
ATPases/metabolismAnimalAnimalsCalcium-TransportingCalcium/*metabolismDiseaseFailure/*drugHeartHumansMiceModels,ReticulumReticulum/metabolismSarcoplasmicSignalTransductionbeta/metabolismtherapy/*metabolismReceptorAdrenergic
(0)
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2Transgenic triadin 1 overexpression alters SR Ca2+ handling and leads to a blunted contractile response to beta-adrenergic agonists
U. Kirchhefer, L. Jones, F. Begrow, P. Boknik, L. Hein, M. Lohse, B. Riemann, W. Schmitz, J. Stypmann, and J. Neumann. Cardiovasc Res, 62 (1): 122-34 (April 2004)Kirchhefer, Uwe Jones, Larry R Begrow, Frank Boknik, Peter Hein, Lutz Lohse, Martin J Riemann, Burkhard Schmitz, Wilhelm Stypmann, Jorg Neumann, Joachim HL-28556/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Netherlands Cardiovascular research Cardiovasc Res. 2004 Apr 1;62(1):122-34..
14 years ago by @pharmawuerz
show all tags
Adrenergic
Animals
Caffeine
Calcium/analysis/*metabolism
Carrier
Confocal
Contraction/*drug
Doppler
Echocardiography,
Electrocardiography
Electrophysiology
Mice
Microscopy,
Muscle
Myocardial
Phosphorylation
Proteins/genetics/*metabolism
Reticulum/*metabolism
Sarcoplasmic
Transgenic
beta-Agonists/*pharmacology
effects
AdrenergicAnimalsCaffeineCalcium/analysis/*metabolismCarrierConfocalContraction/*drugDopplerEchocardiography,ElectrocardiographyElectrophysiologyMiceMicroscopy,MuscleMyocardialPhosphorylationProteins/genetics/*metabolismReticulum/*metabolismSarcoplasmicTransgenicbeta-Agonists/*pharmacologyeffects
(0)
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1Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic receptor
S. Engelhardt, P. Boknik, U. Keller, J. Neumann, M. Lohse, and L. Hein. FASEB J, 15 (14): 2718-20 (December 2001)Engelhardt, S Boknik, P Keller, U Neumann, J Lohse, M J Hein, L United States The FASEB journal : official publication of the Federation of American Societies for Experimental Biology FASEB J. 2001 Dec;15(14):2718-20. Epub 2001 Oct 15..
14 years ago by @pharmawuerz
show all tags
*Membrane
*Mixed
ATPases
ATPases/genetics/metabolism
Animals
Blood
Blotting,
Calcium-Binding
Calcium-Transporting
Calcium/*metabolism
Carrier
Contraction/physiology
Developmental
Expression
Factors
Function
Gene
Humans
Hypertrophy,
Left
Messenger/genetics/metabolism
Mice
Muscle
Myocardial
Myocardium/cytology/*metabolism
Oxygenases
Pressure/physiology
Proteins
Proteins/genetics/metabolism
RNA,
Regulation
Regulation,
Reticulum
Reticulum/metabolism
Sarcoplasmic
Time
Transgenic
Ventricular/genetics/metabolism/physiopathology
Western
beta-1/*genetics/physiology
Receptor
Adrenergic
*Membrane*MixedATPasesATPases/genetics/metabolismAnimalsBloodBlotting,Calcium-BindingCalcium-TransportingCalcium/*metabolismCarrierContraction/physiologyDevelopmentalExpressionFactorsFunctionGeneHumansHypertrophy,LeftMessenger/genetics/metabolismMiceMuscleMyocardialMyocardium/cytology/*metabolismOxygenasesPressure/physiologyProteinsProteins/genetics/metabolismRNA,RegulationRegulation,ReticulumReticulum/metabolismSarcoplasmicTimeTransgenicVentricular/genetics/metabolism/physiopathologyWesternbeta-1/*genetics/physiologyReceptorAdrenergic
(0)
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1Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.
C. Weber, K. Ginsburg, K. Philipson, T. Shannon, and D. Bers. J. Gen. Physiol., 117 (2): 119--131 (February 2001)
16 years ago by @hake
show all tags
11158165
ATPase,
Action
Adrenergic
Allosteric
Animals,
Biological
Biological,
Caffeine,
Calcium
Calcium,
Cardiac,
Cardiovascular,
Cell
Cells,
Channels,
Computer
Congestive,
Contraction,
Cultured,
Cytosol,
Diastole,
Dogs,
Electric
Exchanger,
Failure,
Ferrets,
Fibers,
Gov't,
Heart
Heart,
Humans,
Ion
Isoproterenol,
Kinetics,
Membrane
Membrane,
Mice,
Models,
Muscle
Mutagenesis,
Myocardial
Myocardium,
Myocytes,
Nickel,
Non-U.S.
P.H.S.,
Potentials,
Rabbits,
Regulation,
Research
Reticulum,
Sarcoplasmic
Signaling,
Simulation,
Sodium-Calcium
Stimulation,
Support,
Tetracaine,
Transport,
U.S.
Ventricles,
beta-Agonists,
{C}a$^{2+}$-Transporting
11158165ATPase,ActionAdrenergicAllostericAnimals,BiologicalBiological,Caffeine,CalciumCalcium,Cardiac,Cardiovascular,CellCells,Channels,ComputerCongestive,Contraction,Cultured,Cytosol,Diastole,Dogs,ElectricExchanger,Failure,Ferrets,Fibers,Gov't,HeartHeart,Humans,IonIsoproterenol,Kinetics,MembraneMembrane,Mice,Models,MuscleMutagenesis,MyocardialMyocardium,Myocytes,Nickel,Non-U.S.P.H.S.,Potentials,Rabbits,Regulation,ResearchReticulum,SarcoplasmicSignaling,Simulation,Sodium-CalciumStimulation,Support,Tetracaine,Transport,U.S.Ventricles,beta-Agonists,{C}a$^{2+}$-Transporting
(0)
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1Ca$^2+$ scraps: local depletions of free Ca$^2+$ in cardiac sarcoplasmic reticulum during contractions leave substantial Ca$^2+$ reserve.
T. Shannon, T. Guo, and D. Bers. Circ. Res., 93 (1): 40--45 (July 2003)
16 years ago by @hake
show all tags
12855669
Action
Adrenergic
Animals,
Caffeine,
Calcium
Calcium,
Cardiac,
Cardiovascular,
Cell
Cells,
Computer
Congestive,
Contraction,
Cultured,
Cytosol,
Electric
Failure,
Gov't,
Heart
Humans,
Ion
Isoproterenol,
Membrane
Membrane,
Models,
Myocardial
Myocardium,
Myocytes,
Non-U.S.
P.H.S.,
Potentials,
Rabbits,
Research
Reticulum,
Sarcoplasmic
Signaling,
Simulation,
Stimulation,
Support,
Tetracaine,
Transport,
U.S.
Ventricles,
beta-Agonists,
12855669ActionAdrenergicAnimals,Caffeine,CalciumCalcium,Cardiac,Cardiovascular,CellCells,ComputerCongestive,Contraction,Cultured,Cytosol,ElectricFailure,Gov't,HeartHumans,IonIsoproterenol,MembraneMembrane,Models,MyocardialMyocardium,Myocytes,Non-U.S.P.H.S.,Potentials,Rabbits,ResearchReticulum,SarcoplasmicSignaling,Simulation,Stimulation,Support,Tetracaine,Transport,U.S.Ventricles,beta-Agonists,
(0)
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1Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration.
T. Shannon, K. Ginsburg, and D. Bers. Biophys. J., 78 (1): 334--343 (January 2000)
16 years ago by @hake
show all tags
10620297
AMP-Dependent
ATPase,
Action
Activation,
Adenosine
Adrenergic
Allosteric
Animals,
Binding,
Biological
Biological,
Caffeine,
Calcium
Calcium,
Calcium-Binding
Cardiac,
Cardiovascular,
Catalytic
Cell
Cells,
Channels,
Computer
Congestive,
Contraction,
Cultured,
Cyclic
Cytosol,
Diastole,
Dogs,
Domain,
Electric
Enzyme
Exchanger,
Factors,
Failure,
Ferrets,
Fibers,
Gov't,
Heart
Heart,
Humans,
Hydrolysis,
Inhibitors,
Intracellular
Ion
Isoproterenol,
Kinases,
Kinetics,
Knockout,
Membrane
Membrane,
Membranes,
Mice,
Microsomes,
Models,
Muscle
Mutagenesis,
Myocardial
Myocardium,
Myocytes,
Nickel,
Non-U.S.
P.H.S.,
Patch-Clamp
Phosphorylation,
Potentials,
Protein
Proteins,
Rabbits,
Red,
Regulation,
Research
Reticulum,
Ruthenium
Sarcoplasmic
Signaling,
Simulation,
Sodium-Calcium
Stimulation,
Support,
Techniques,
Tetracaine,
Thapsigargin,
Thermodynamics,
Time
Transport,
Triphosphate,
U.S.
Ventricles,
beta-Agonists,
{C}a$^{2+}$-Transporting
10620297AMP-DependentATPase,ActionActivation,AdenosineAdrenergicAllostericAnimals,Binding,BiologicalBiological,Caffeine,CalciumCalcium,Calcium-BindingCardiac,Cardiovascular,CatalyticCellCells,Channels,ComputerCongestive,Contraction,Cultured,CyclicCytosol,Diastole,Dogs,Domain,ElectricEnzymeExchanger,Factors,Failure,Ferrets,Fibers,Gov't,HeartHeart,Humans,Hydrolysis,Inhibitors,IntracellularIonIsoproterenol,Kinases,Kinetics,Knockout,MembraneMembrane,Membranes,Mice,Microsomes,Models,MuscleMutagenesis,MyocardialMyocardium,Myocytes,Nickel,Non-U.S.P.H.S.,Patch-ClampPhosphorylation,Potentials,ProteinProteins,Rabbits,Red,Regulation,ResearchReticulum,RutheniumSarcoplasmicSignaling,Simulation,Sodium-CalciumStimulation,Support,Techniques,Tetracaine,Thapsigargin,Thermodynamics,TimeTransport,Triphosphate,U.S.Ventricles,beta-Agonists,{C}a$^{2+}$-Transporting
(0)
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1Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes.
T. Shannon, K. Ginsburg, and D. Bers. Biophys. J., 78 (1): 322--333 (January 2000)
16 years ago by @hake
show all tags
10620296
AMP-Dependent
ATPase,
Action
Activation,
Adenosine
Adrenergic
Allosteric
Animals,
Binding,
Biological
Biological,
Caffeine,
Calcium
Calcium,
Calcium-Binding
Cardiac,
Cardiovascular,
Catalytic
Cell
Cells,
Channels,
Computer
Congestive,
Contraction,
Cultured,
Cyclic
Cytosol,
Diastole,
Dogs,
Domain,
Electric
Enzyme
Exchanger,
Factors,
Failure,
Ferrets,
Fibers,
Gov't,
Heart
Heart,
Humans,
Hydrolysis,
Inhibitors,
Intracel,
Intracellular
Ion
Isoproterenol,
Kinases,
Kinetics,
Knockout,
Membrane
Membrane,
Membranes,
Mice,
Microsomes,
Models,
Muscle
Mutagenesis,
Myocardial
Myocardium,
Myocytes,
Nickel,
Non-U.S.
P.H.S.,
Patch-Clamp
Phosphorylation,
Potentials,
Protein
Proteins,
Rabbits,
Red,
Regulation,
Research
Reticulum,
Ruthenium
Sarcoplasmic
Signaling,
Simulation,
Sodium-Calcium
Stimulation,
Support,
Techniques,
Tetracaine,
Thapsigargin,
Thermodynamics,
Time
Transport,
Triphosphate,
Troponin,
U.S.
Ventricles,
beta-Agonists,
lular
{C}a$^{2+}$-Transporting
10620296AMP-DependentATPase,ActionActivation,AdenosineAdrenergicAllostericAnimals,Binding,BiologicalBiological,Caffeine,CalciumCalcium,Calcium-BindingCardiac,Cardiovascular,CatalyticCellCells,Channels,ComputerCongestive,Contraction,Cultured,CyclicCytosol,Diastole,Dogs,Domain,ElectricEnzymeExchanger,Factors,Failure,Ferrets,Fibers,Gov't,HeartHeart,Humans,Hydrolysis,Inhibitors,Intracel,IntracellularIonIsoproterenol,Kinases,Kinetics,Knockout,MembraneMembrane,Membranes,Mice,Microsomes,Models,MuscleMutagenesis,MyocardialMyocardium,Myocytes,Nickel,Non-U.S.P.H.S.,Patch-ClampPhosphorylation,Potentials,ProteinProteins,Rabbits,Red,Regulation,ResearchReticulum,RutheniumSarcoplasmicSignaling,Simulation,Sodium-CalciumStimulation,Support,Techniques,Tetracaine,Thapsigargin,Thermodynamics,TimeTransport,Triphosphate,Troponin,U.S.Ventricles,beta-Agonists,lular{C}a$^{2+}$-Transporting
(0)
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1Phospholamban decreases the energetic efficiency of the sarcoplasmic reticulum Ca pump.
T. Shannon, G. Chu, E. Kranias, and D. Bers. J. Biol. Chem., 276 (10): 7195--7201 (March 2001)
16 years ago by @hake
show all tags
11087739
AMP-Dependent
ATPase,
Action
Activation,
Adenosine
Adrenergic
Allosteric
Animals,
Binding,
Biological
Biological,
Caffeine,
Calcium
Calcium,
Calcium-Binding
Cardiac,
Cardiovascular,
Catalytic
Cell
Cells,
Channels,
Computer
Congestive,
Contraction,
Cultured,
Cyclic
Cytosol,
Diastole,
Dogs,
Domain,
Electric
Enzyme
Exchanger,
Factors,
Failure,
Ferrets,
Fibers,
Gov't,
Heart
Heart,
Humans,
Hydrolysis,
Inhibitors,
Intracellular
Ion
Isoproterenol,
Kinases,
Kinetics,
Knockout,
Membrane
Membrane,
Membranes,
Mice,
Microsomes,
Models,
Muscle
Mutagenesis,
Myocardial
Myocardium,
Myocytes,
Nickel,
Non-U.S.
P.H.S.,
Phosphorylation,
Potentials,
Protein
Proteins,
Rabbits,
Red,
Regulation,
Research
Reticulum,
Ruthenium
Sarcoplasmic
Signaling,
Simulation,
Sodium-Calcium
Stimulation,
Support,
Tetracaine,
Thapsigargin,
Thermodynamics,
Time
Transport,
Triphosphate,
U.S.
Ventricles,
beta-Agonists,
{C}a$^{2+}$-Transporting
11087739AMP-DependentATPase,ActionActivation,AdenosineAdrenergicAllostericAnimals,Binding,BiologicalBiological,Caffeine,CalciumCalcium,Calcium-BindingCardiac,Cardiovascular,CatalyticCellCells,Channels,ComputerCongestive,Contraction,Cultured,CyclicCytosol,Diastole,Dogs,Domain,ElectricEnzymeExchanger,Factors,Failure,Ferrets,Fibers,Gov't,HeartHeart,Humans,Hydrolysis,Inhibitors,IntracellularIonIsoproterenol,Kinases,Kinetics,Knockout,MembraneMembrane,Membranes,Mice,Microsomes,Models,MuscleMutagenesis,MyocardialMyocardium,Myocytes,Nickel,Non-U.S.P.H.S.,Phosphorylation,Potentials,ProteinProteins,Rabbits,Red,Regulation,ResearchReticulum,RutheniumSarcoplasmicSignaling,Simulation,Sodium-CalciumStimulation,Support,Tetracaine,Thapsigargin,Thermodynamics,TimeTransport,Triphosphate,U.S.Ventricles,beta-Agonists,{C}a$^{2+}$-Transporting
(0)
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1Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity.
J. Sande, I. Sjaastad, I. Hoen, J. B�kenes, T. T�nnessen, E. Holt, P. Lunde, and G. Christensen. Cardiovasc. Res., 53 (2): 382-91 (February 2002)
16 years ago by @hake
show all tags
11827689
AMP-Dependent
ATPase,
Adrenergic
Animals,
Calcium,
Calcium-Binding
Congestive,
Cyclic
Enzyme
Failure,
Fluid,
Forskolin,
Gov't,
Heart
Homeostasis,
Immunoblotting,
Infarction,
Inhibitors,
Intracellular
Isoproterenol,
Isoquinolines,
Kinases,
Male,
Myocardial
Myocardium,
Non-U.S.
Phosphorylation,
Protein
Proteins,
Rats,
Research
Reticulum,
Sarcoplasmic
Sulfonamides,
Support,
Wistar,
beta-Agonists,
{C}a$^{2+}$-Transporting
11827689AMP-DependentATPase,AdrenergicAnimals,Calcium,Calcium-BindingCongestive,CyclicEnzymeFailure,Fluid,Forskolin,Gov't,HeartHomeostasis,Immunoblotting,Infarction,Inhibitors,IntracellularIsoproterenol,Isoquinolines,Kinases,Male,MyocardialMyocardium,Non-U.S.Phosphorylation,ProteinProteins,Rats,ResearchReticulum,SarcoplasmicSulfonamides,Support,Wistar,beta-Agonists,{C}a$^{2+}$-Transporting
(0)
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1Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness.
S. Pogwizd, K. Schlotthauer, L. Li, W. Yuan, and D. Bers. Circ. Res., 88 (11): 1159--1167 (June 2001)
16 years ago by @hake
show all tags
11397771
A,
Adrenergic
Animal,
Animals,
Arrhythmia,
Caffeine,
Calcium,
Cells,
Channels,
Congestive,
Contraction,
Cultured,
Disease
Down-Regulation,
Dysfunction,
Exchanger,
Failure,
Gov't,
Heart
Inwardly
Isoproterenol,
Left,
Membrane
Models,
Myocardial
P.H.S.,
Patch-Clamp
Potassium
Potassium,
Potentials,
Propranolol,
Rabbits,
Receptors,
Rectifying,
Research
Reticulum,
Sarcoplasmic
Sodium,
Sodium-Calcium
Support,
Techniques,
U.S.
Up-Regulation,
Ventricular
beta,
beta-Agonists,
beta-Antagonists,
drenergic,
11397771A,AdrenergicAnimal,Animals,Arrhythmia,Caffeine,Calcium,Cells,Channels,Congestive,Contraction,Cultured,DiseaseDown-Regulation,Dysfunction,Exchanger,Failure,Gov't,HeartInwardlyIsoproterenol,Left,MembraneModels,MyocardialP.H.S.,Patch-ClampPotassiumPotassium,Potentials,Propranolol,Rabbits,Receptors,Rectifying,ResearchReticulum,SarcoplasmicSodium,Sodium-CalciumSupport,Techniques,U.S.Up-Regulation,Ventricularbeta,beta-Agonists,beta-Antagonists,drenergic,
(0)
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1Dyssynchronous Ca$^2+$ sparks in myocytes from infarcted hearts.
S. Litwin, D. Zhang, and J. Bridge. Circ. Res., 87 (11): 1040--1047 (November 2000)
16 years ago by @hake
show all tags
11090539
Action
Adrenergic
Animal,
Animals,
Calcium
Calcium,
Channels,
Disease
Dysfunction,
Gov't,
Infarction,
Isoproterenol,
L-Type,
Left,
Male,
Models,
Myocardial
Myocardium,
Non-P.H.S.,
Non-U.S.
P.H.S.,
Patch-Clamp
Potentials,
Processes,
Rabbits,
Research
Reticulum,
Sarcoplasmic
Signaling,
Stochastic
Support,
Techniques,
U.S.
Ventricular
beta-Agonists,
11090539ActionAdrenergicAnimal,Animals,CalciumCalcium,Channels,DiseaseDysfunction,Gov't,Infarction,Isoproterenol,L-Type,Left,Male,Models,MyocardialMyocardium,Non-P.H.S.,Non-U.S.P.H.S.,Patch-ClampPotentials,Processes,Rabbits,ResearchReticulum,SarcoplasmicSignaling,StochasticSupport,Techniques,U.S.Ventricularbeta-Agonists,
(0)
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1Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure.
A. G�mez, H. Valdivia, H. Cheng, M. Lederer, L. Santana, M. Cannell, S. McCune, R. Altschuld, and W. Lederer. Science, 276 (5313): 800-6 (May 1997)
16 years ago by @hake
show all tags
9157553
Adrenergic
Animals,
Blockers,
Calcium
Calcium,
Cardiomegaly,
Cell
Channel
Channel,
Channels,
Confocal,
Congestive,
Contraction,
Failure,
Gov't,
Heart
Hypertension,
Inbred
Isoproterenol,
L-Type,
Membrane,
Microscopy,
Muscle
Myocardial
Myocardium,
Nifedipine,
Non-U.S.
P.H.S.,
Patch-Clamp
Proteins,
Rats,
Receptor
Release
Research
Reticulum,
Ryanodine
Sarcoplasmic
Strains,
Support,
Techniques,
U.S.
beta-Agonists,
9157553AdrenergicAnimals,Blockers,CalciumCalcium,Cardiomegaly,CellChannelChannel,Channels,Confocal,Congestive,Contraction,Failure,Gov't,HeartHypertension,InbredIsoproterenol,L-Type,Membrane,Microscopy,MuscleMyocardialMyocardium,Nifedipine,Non-U.S.P.H.S.,Patch-ClampProteins,Rats,ReceptorReleaseResearchReticulum,RyanodineSarcoplasmicStrains,Support,Techniques,U.S.beta-Agonists,
(0)
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1Regulation of cardiac sodium-calcium exchanger by beta-adrenergic agonists.
J. Fan, Y. Shuba, and M. Morad. Proc. Natl. Acad. Sci. U. S. A., 93 (11): 5527-32 (May 1996)
16 years ago by @hake
show all tags
8-Bromo
8643609
AMP,
ATPase,
Action
Adenosine
Adenylate
Adrenergic
Adrenergic,
Animals,
Calcium,
Carrier
Comparative
Contraction,
Cyclase,
Cyclic
Exchanger,
Forskolin,
Gov't,
Heart
Heart,
In
Isoproterenol,
Kinetics,
Membrane
Monophosphate,
Myocardial
Nickel,
Non-U.S.
P.H.S.,
Patch-Clamp
Potentials,
Propranolol,
Proteins,
Rana
Receptors,
Research
Reticulum,
Sarcoplasmic
Sodium-Calcium
Study,
Support,
Techniques,
Theophylline,
U.S.
Ventricles,
Vitro,
beta,
beta-Agonists,
beta-Antagonists,
pipiens,
{C}a$^{2+}$-Transporting
8-Bromo8643609AMP,ATPase,ActionAdenosineAdenylateAdrenergicAdrenergic,Animals,Calcium,CarrierComparativeContraction,Cyclase,CyclicExchanger,Forskolin,Gov't,HeartHeart,InIsoproterenol,Kinetics,MembraneMonophosphate,MyocardialNickel,Non-U.S.P.H.S.,Patch-ClampPotentials,Propranolol,Proteins,RanaReceptors,ResearchReticulum,SarcoplasmicSodium-CalciumStudy,Support,Techniques,Theophylline,U.S.Ventricles,Vitro,beta,beta-Agonists,beta-Antagonists,pipiens,{C}a$^{2+}$-Transporting
(0)
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1Phospholemman-mediated activation of Na/K-ATPase limits Nai and inotropic state during beta-adrenergic stimulation in mouse ventricular myocytes.
S. Despa, A. Tucker, and D. Bers. Circulation, 117 (14): 1849--1855 (April 2008)
16 years ago by @hake
show all tags
ATPases,
Activation,
Adrenergic
Adrenergic,
Agents,
Animals,
Animals;
Arrhythmias,
Artificial;
C57BL;
Calcium
Calcium-Transporting
Cardiac
Cardiac,
Cardiotonic
Channel
Congenic;
Enzyme
Gating,
Heart
Inbred
Ion
Isoproterenol,
Knockout;
Membrane
Mice,
Mice;
Myocytes,
Pacing,
Phosphoproteins,
Phosphorylation;
Post-Translational;
Processing,
Protein
Proteins,
Receptors,
Reticulum
Sarcoplasmic
Signaling;
Sodium,
Ventricles;
beta,
beta-Agonists,
chemically
drug
effects/metabolism;
effects;
induced/physiopathology;
metabolism
physiology;
toxicity;
ATPases,Activation,AdrenergicAdrenergic,Agents,Animals,Animals;Arrhythmias,Artificial;C57BL;CalciumCalcium-TransportingCardiacCardiac,CardiotonicChannelCongenic;EnzymeGating,HeartInbredIonIsoproterenol,Knockout;MembraneMice,Mice;Myocytes,Pacing,Phosphoproteins,Phosphorylation;Post-Translational;Processing,ProteinProteins,Receptors,ReticulumSarcoplasmicSignaling;Sodium,Ventricles;beta,beta-Agonists,chemicallydrugeffects/metabolism;effects;induced/physiopathology;metabolismphysiology;toxicity;
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2Ca2+ cycling and new therapeutic approaches for heart failure

2Transgenic triadin 1 overexpression alters SR Ca2+ handling and leads to a blunted contractile response to beta-adrenergic agonists

1Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic receptor

1Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.

1Ca$^2+$ scraps: local depletions of free Ca$^2+$ in cardiac sarcoplasmic reticulum during contractions leave substantial Ca$^2+$ reserve.

1Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration.

1Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes.

1Phospholamban decreases the energetic efficiency of the sarcoplasmic reticulum Ca pump.

1Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity.

1Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness.

1Dyssynchronous Ca$^2+$ sparks in myocytes from infarcted hearts.

1Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure.

1Regulation of cardiac sodium-calcium exchanger by beta-adrenergic agonists.

1Phospholemman-mediated activation of Na/K-ATPase limits Nai and inotropic state during beta-adrenergic stimulation in mouse ventricular myocytes.

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