Have you noticed that the occasional website you visit has sharp, pixelated fonts? The problem is that websites like this are improperly designed and are forcing the use of Helvetica, which does not anti-alias (sub-pixel font smoothing). The fix for this is to force Helvetica fonts to change to the default sans-serif font, which can be easily anti-aliased.
E. Ferain, and R. Legras. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, (2003)Ionizing Radiation and Polymers.