tag :: Gene protein drug

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2Identification of disease treatment mechanisms through the multiscale interactome
C. Ruiz, M. Zitnik, и J. Leskovec. Nature communications, 12 (1): 1--15 (2021)
3 лет назад , @nalab
drug
citedby:scholar:count:10
toread
citedby:scholar:timestamp:2021-10-6
gene
project:contraception
from:becker
protein
interactome
interaction
drugcitedby:scholar:count:10toreadcitedby:scholar:timestamp:2021-10-6geneproject:contraceptionfrom:beckerproteininteractomeinteraction
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2Identification of disease treatment mechanisms through the multiscale interactome
C. Ruiz, M. Zitnik, и J. Leskovec. Nature communications, 12 (1): 1--15 (2021)
3 лет назад , @becker
citedby:scholar:count:10
citedby:scholar:timestamp:2021-10-6
drug
gene
interaction
interactome
project:contraception
protein
toread
citedby:scholar:count:10citedby:scholar:timestamp:2021-10-6druggeneinteractioninteractomeproject:contraceptionproteintoread
(0)
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1Autotaxin is expressed in FLT3-ITD positive acute myeloid leukemia and hematopoietic stem cells and promotes cell migration and proliferation.
C. Ortlepp, C. Steudel, C. Heiderich, S. Koch, A. Jacobi, M. Ryser, S. Brenner, M. Bornhäuser, B. Brors, W. Hofmann и 2 other автор(ы). Exp Hematol, 41 (5): 444--461.e4 (мая 2013)
10 лет назад , @bbrors
/&/
3,
Acute
Analysis;
Array
Blotting,
Cell
Cells,
Cells;
Chain
Cultured;
Diester
Disease;
Expression
Gene
Hematopoietic
Humans;
Hydrolases,
Indoles,
Inhibitors,
K562
Kinase
Leukemia,
Leukemic,
Line,
Line;
Lysophosphatidylcholines,
Lysophospholipids,
Movement,
Mutation;
Myeloid,
Oligonucleotide
Phosphoric
Polymerase
Profiling;
Proliferation;
Protein
Reaction;
Regulation,
Repeat
Reverse
Sequence
Sequences,
Staurosporine,
Stem
Tandem
Transcriptase
Tumor;
Tyrosine
Western;
analogs
derivatives/pharmacology;
drug
effects/genetics;
effects;
fms-Like
genetics
genetics/metabolism/pathology;
genetics/metabolism;
genetics;
metabolism/pharmacology;
metabolism;
pharmacology;
/&/3,AcuteAnalysis;ArrayBlotting,CellCells,Cells;ChainCultured;DiesterDisease;ExpressionGeneHematopoieticHumans;Hydrolases,Indoles,Inhibitors,K562KinaseLeukemia,Leukemic,Line,Line;Lysophosphatidylcholines,Lysophospholipids,Movement,Mutation;Myeloid,OligonucleotidePhosphoricPolymeraseProfiling;Proliferation;ProteinReaction;Regulation,RepeatReverseSequenceSequences,Staurosporine,StemTandemTranscriptaseTumor;TyrosineWestern;analogsderivatives/pharmacology;drugeffects/genetics;effects;fms-Likegeneticsgenetics/metabolism/pathology;genetics/metabolism;genetics;metabolism/pharmacology;metabolism;pharmacology;
(0)
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1Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
M. Kool, D. Jones, N. Jäger, P. Northcott, T. Pugh, V. Hovestadt, R. Piro, L. Esparza, S. Markant, M. Remke и 67 other автор(ы). Cancer Cell, 25 (3): 393--405 (марта 2014)
10 лет назад , @bbrors
/&/
3-Kinases,
Adolescent;
Adult
Adult;
Animals;
Base
Biphenyl
Cell
Cerebellar
Child,
Child;
Compounds,
Copy
DEAD-box
DNA
Data;
Drug
Expression
Factors,
Female;
G-Protein-Coupled,
Gene
Genetic,
Hedgehog
Helicases,
High-Throughput
Humans;
Inbred
Infant;
Kruppel-Like
Male;
Medulloblastoma,
Mice,
Mice;
Molecular
NOD;
Neoplasm
Neoplasm,
Neoplasms,
Nuclear
Nucleotide
Number
Oncogene
Phosphatidylinositol
Preschool;
Profiling;
Promoter
Protein
Proteins
Proteins,
Proto-Oncogene
Pyridines,
RNA
Receptors,
Regions,
Repressor
Resistance,
SCID;
Sequence
Sequence;
Sequencing;
Signal
Suppressor
Surface,
Telomerase,
Transcription
Transduction,
Transplantation;
Tumor
Variations,
Young
antagonists
c-akt,
drug
genetics/metabolism;
genetics;
inhibitors/genetics;
p53,
therapeutic
therapy/genetics;
use;
/&/3-Kinases,Adolescent;AdultAdult;Animals;BaseBiphenylCellCerebellarChild,Child;Compounds,CopyDEAD-boxDNAData;DrugExpressionFactors,Female;G-Protein-Coupled,GeneGenetic,HedgehogHelicases,High-ThroughputHumans;InbredInfant;Kruppel-LikeMale;Medulloblastoma,Mice,Mice;MolecularNOD;NeoplasmNeoplasm,Neoplasms,NuclearNucleotideNumberOncogenePhosphatidylinositolPreschool;Profiling;PromoterProteinProteinsProteins,Proto-OncogenePyridines,RNAReceptors,Regions,RepressorResistance,SCID;SequenceSequence;Sequencing;SignalSuppressorSurface,Telomerase,TranscriptionTransduction,Transplantation;TumorVariations,Youngantagonistsc-akt,druggenetics/metabolism;genetics;inhibitors/genetics;p53,therapeutictherapy/genetics;use;
(0)
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1The Forkhead factor FoxQ1 influences epithelial differentiation.
A. Feuerborn, P. Srivastava, S. Küffer, W. Grandy, T. Sijmonsma, N. Gretz, B. Brors, и H. Gröne. J Cell Physiol, 226 (3): 710--719 (марта 2011)
10 лет назад , @bbrors
Actins,
Animals;
Cell
Cells,
Communication,
Cyclin-Dependent
Differentiation,
Epithelial
Expression
Factor
Factors,
Forkhead
G1
Gene
Growth
Kinases,
Knockdown
Mice;
Microfilament
Movement,
Phase,
Proliferation,
Protein
Proteins,
Regulation,
Shape,
Signal
Size,
Techniques;
Transcription
Transduction,
Transforming
Transport,
beta1,
cytology/drug
drug
effects/metabolism;
effects;
genetics/metabolism;
metabolism;
pharmacology
Actins,Animals;CellCells,Communication,Cyclin-DependentDifferentiation,EpithelialExpressionFactorFactors,ForkheadG1GeneGrowthKinases,KnockdownMice;MicrofilamentMovement,Phase,Proliferation,ProteinProteins,Regulation,Shape,SignalSize,Techniques;TranscriptionTransduction,TransformingTransport,beta1,cytology/drugdrugeffects/metabolism;effects;genetics/metabolism;metabolism;pharmacology
(0)
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1Sequential expression of c-fos protooncogene, TNF-alpha, and dynorphin genes in spinal cord following experimental traumatic injury.
A. Yakovlev, и A. Faden. Mol Chem Neuropathol, 23 (2-3): 179--190 (1994)
10 лет назад , @ar0berts
,
Sprague-Dawley;
Animals;
Base
Sequence;
Dynorphins,
biosynthesis/genetics;
Gene
Expression,
physiology;
Genes,
fos,
drug
effects;
Histones,
Male;
Molecular
Sequence
Data;
Polymerase
Chain
Reaction;
Protein
Precursors,
RNA,
Messenger,
biosynthesis;
Rats;
Spinal
Cord
Injuries,
metabolism;
Transcription,
Genetic;
Tumor
Necrosis
Factor-alpha,
biosynthesis/genetics
,Sprague-Dawley;Animals;BaseSequence;Dynorphins,biosynthesis/genetics;GeneExpression,physiology;Genes,fos,drugeffects;Histones,Male;MolecularSequenceData;PolymeraseChainReaction;ProteinPrecursors,RNA,Messenger,biosynthesis;Rats;SpinalCordInjuries,metabolism;Transcription,Genetic;TumorNecrosisFactor-alpha,biosynthesis/genetics
(0)
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1Phenotype and gene expression of human mesenchymal stem cells in alginate scaffolds.
S. Duggal, K. FrÃ¸nsdal, K. SzÃ¶ke, A. Shahdadfar, J. Melvik, и J. Brinchmann. Tissue Eng Part A, 15 (7): 1763--1773 (июля 2009)
13 лет назад , @pawelsikorski
Acid,
Acids,
Adhesion,
Adolescent;
Adult;
Alginates,
Binding,
Cell
Cells,
Cultured;
Differentiation,
Expression
Fibroblasts,
Gene
Glucuronic
Hexuronic
Humans;
Immobilized,
Integrins,
Intracellular
Lineage,
Mesenchymal
Oligopeptides,
Phenotype;
Plastics;
Proliferation,
Protein
Regulation,
Scaffolds
Shape,
Signal
Space,
Stem
Survival,
Tissue
Transduction,
cytology/drug
drug
effects/genetics;
effects/metabolism;
effects;
metabolism;
pharmacology;
Acid,Acids,Adhesion,Adolescent;Adult;Alginates,Binding,CellCells,Cultured;Differentiation,ExpressionFibroblasts,GeneGlucuronicHexuronicHumans;Immobilized,Integrins,IntracellularLineage,MesenchymalOligopeptides,Phenotype;Plastics;Proliferation,ProteinRegulation,ScaffoldsShape,SignalSpace,StemSurvival,TissueTransduction,cytology/drugdrugeffects/genetics;effects/metabolism;effects;metabolism;pharmacology;
(0)
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1Expression, pharmacological profile, and functional coupling of A2B receptors in a recombinant system and in peripheral blood cells using a novel selective antagonist radioligand, 3HMRE 2029-F20
S. Gessi, K. Varani, S. Merighi, E. Cattabriga, C. Pancaldi, Y. Szabadkai, R. Rizzuto, K. Klotz, E. Leung, S. Lennan и 2 other автор(ы). Mol Pharmacol, 67 (6): 2137-47 (июня 2005)Gessi, Stefania Varani, Katia Merighi, Stefania Cattabriga, Elena Pancaldi, Cecilia Szabadkai, Youri Rizzuto, Rosario Klotz, Karl-Norbert Leung, Edward Mac Lennan, Stephen Baraldi, Pier Giovanni Borea, Pier Andrea Comparative Study United States Molecular pharmacology Mol Pharmacol. 2005 Jun;67(6):2137-47. Epub 2005 Mar 23..
14 лет назад , @pharmawuerz
&
A2B/*antagonists
Acetamides/*pharmacology
Adenosine
Adenosine-5'-(N-ethylcarboxamide)/pharmacology
Binding/drug
Cell
Dose-Response
Drug
Expression
Gene
Humans
Leukocytes,
Line
Mononuclear/*drug
Protein
Proteins/antagonists
Purines/*pharmacology
Pyrazoles/*pharmacology
Recombinant
Regulation/drug
Relationship,
effects/metabolism
effects/physiology
inhibitors/*biosynthesis/genetics
inhibitors/biosynthesis/genetics
Receptor
&A2B/*antagonistsAcetamides/*pharmacologyAdenosineAdenosine-5'-(N-ethylcarboxamide)/pharmacologyBinding/drugCellDose-ResponseDrugExpressionGeneHumansLeukocytes,LineMononuclear/*drugProteinProteins/antagonistsPurines/*pharmacologyPyrazoles/*pharmacologyRecombinantRegulation/drugRelationship,effects/metabolismeffects/physiologyinhibitors/*biosynthesis/geneticsinhibitors/biosynthesis/geneticsReceptor
(0)
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2EBIMed - text crunching to gather facts for proteins from Medline.
D. Rebholz-Schuhmann, H. Kirsch, M. Arregui, S. Gaudan, M. Riethoven, и P. Stoehr. Bioinformatics, 23 (2): 237-244 (2007)
14 лет назад , @huiyangsfsu
CAT
CAT-IR
CAT-NER
CAT-ONLINE-SW
CAT-REL-COOR
CAT-VIZ
EBIMed
annotation
drug
gene
protein
species
CATCAT-IRCAT-NERCAT-ONLINE-SWCAT-REL-COORCAT-VIZEBIMedannotationdruggeneproteinspecies
(0)
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2Surrogate predictive biomarkers for response to anti-EGFR agents: state of the art and challenges
F. Cappuzzo, L. Toschi, G. Finocchiaro, C. Ligorio, и A. Santoro. Int.J.Biol.Markers, 22 (1 Suppl 4): S10-S23 (2007)
15 лет назад , @jabreftest
inhibitors
Monoclonal
Tyrosine
antagonists
c-akt
Predictive
of
Phosphoproteins
Protein-Tyrosine
Resistance
protein
Drug
Protein
Epidermal
Value
&
Factor
identify
erbB-3
erbB-2
effects
Carcinoma
Neoplasms
Non-Small-Cell
Tests
Biological
therapy
Mutation
therapeutic
Human
Humans
use
analysis
Kinases
response
Growth
Neoplasm
Inhibitors
Markers
Kinase
drug
Gene
Quinazolines
Receptor
genetics
Antibodies
Lung
Dosage
Proto-Oncogene
Proteins
Immunohistochemistry
inhibitorsMonoclonalTyrosineantagonistsc-aktPredictiveofPhosphoproteinsProtein-TyrosineResistanceproteinDrugProteinEpidermalValue&FactoridentifyerbB-3erbB-2effectsCarcinomaNeoplasmsNon-Small-CellTestsBiologicaltherapyMutationtherapeuticHumanHumansuseanalysisKinasesresponseGrowthNeoplasmInhibitorsMarkersKinasedrugGeneQuinazolinesReceptorgeneticsAntibodiesLungDosageProto-OncogeneProteinsImmunohistochemistry
(0)
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2Surrogate predictive biomarkers for response to anti-EGFR agents: state of the art and challenges
F. Cappuzzo, L. Toschi, G. Finocchiaro, C. Ligorio, и A. Santoro. Int.J.Biol.Markers, 22 (1 Suppl 4): S10-S23 (2007)
15 лет назад , @kanefendt
&
Antibodies
Biological
Carcinoma
Dosage
Drug
Epidermal
Factor
Gene
Growth
Human
Humans
Immunohistochemistry
Inhibitors
Kinase
Kinases
Lung
Markers
Monoclonal
Mutation
Neoplasm
Neoplasms
Non-Small-Cell
Phosphoproteins
Predictive
Protein
Protein-Tyrosine
Proteins
Proto-Oncogene
Quinazolines
Receptor
Resistance
Tests
Tyrosine
Value
analysis
antagonists
c-akt
drug
effects
erbB-2
erbB-3
genetics
identify
inhibitors
of
protein
response
therapeutic
therapy
use
&AntibodiesBiologicalCarcinomaDosageDrugEpidermalFactorGeneGrowthHumanHumansImmunohistochemistryInhibitorsKinaseKinasesLungMarkersMonoclonalMutationNeoplasmNeoplasmsNon-Small-CellPhosphoproteinsPredictiveProteinProtein-TyrosineProteinsProto-OncogeneQuinazolinesReceptorResistanceTestsTyrosineValueanalysisantagonistsc-aktdrugeffectserbB-2erbB-3geneticsidentifyinhibitorsofproteinresponsetherapeutictherapyuse
(0)
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1Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome
M. Cuadrado, P. Buendia, F. Velasco, M. Aguirre, N. Barbarroja, L. Torres, M. Khamashta, и C. Lopez-Pedrera. J.Thromb.Haemost., 4 (11): 2461-2469 (2006)
15 лет назад , @kanefendt
&
A
Adolescent
Adult
Aged
Antibodies
Antiphospholipid
Cells
Cultured
Endothelial
Enzyme
Expression
Factor
Female
Gene
Growth
Human
Humans
Imidazoles
Inhibitors
Kinase
Kinases
MAP
Male
Middle
Mitogen-Activated
Monocytes
Phenotype
Protein
Pyridines
Receptor-1
Regulation
Research
Signaling
Syndrome
System
Thromboplastin
Thrombosis
Tyrosine
Vascular
antagonists
biosynthesis
cells
drug
effects
inhibitors
metabolism
p38
pathology
pharmacology
protein
&AAdolescentAdultAgedAntibodiesAntiphospholipidCellsCulturedEndothelialEnzymeExpressionFactorFemaleGeneGrowthHumanHumansImidazolesInhibitorsKinaseKinasesMAPMaleMiddleMitogen-ActivatedMonocytesPhenotypeProteinPyridinesReceptor-1RegulationResearchSignalingSyndromeSystemThromboplastinThrombosisTyrosineVascularantagonistsbiosynthesiscellsdrugeffectsinhibitorsmetabolismp38pathologypharmacologyprotein
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2Identification of disease treatment mechanisms through the multiscale interactome

2Identification of disease treatment mechanisms through the multiscale interactome

1Autotaxin is expressed in FLT3-ITD positive acute myeloid leukemia and hematopoietic stem cells and promotes cell migration and proliferation.

1Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.

1The Forkhead factor FoxQ1 influences epithelial differentiation.

1Sequential expression of c-fos protooncogene, TNF-alpha, and dynorphin genes in spinal cord following experimental traumatic injury.

1Phenotype and gene expression of human mesenchymal stem cells in alginate scaffolds.

1Expression, pharmacological profile, and functional coupling of A2B receptors in a recombinant system and in peripheral blood cells using a novel selective antagonist radioligand, 3HMRE 2029-F20

2EBIMed - text crunching to gather facts for proteins from Medline.

2Surrogate predictive biomarkers for response to anti-EGFR agents: state of the art and challenges

2Surrogate predictive biomarkers for response to anti-EGFR agents: state of the art and challenges

1Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome

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