Ketamine blocks a brain protein called the N-methyl-D-aspartic acid (NMDA) receptor. Previous studies have shown that agents that block the NMDA receptor reduce depression-like behaviors in animals.
This CURRENTLY ENROLLING study will test whether a single dose of ketamine - a drug that blocks a brain receptor called NMDA - can cause a rapid (next day) antidepressant effect in patients with major depression. Several medications are effective for trea
After reading Michael Fumento's article several points need to be made. In the first place, after clicking the link and reading the study itself, it bears emphasizing that the sample size-18 patients, is extremely small. This by definition makes it diffic
Dr. Zarate and colleagues said a single injection of ketamine, which targets the N-methlyl-D-aspartate (NMDA) receptor, can eliminate depression symptoms within 110 minutes.
17 depressed patients randomly assigned to receive either an injection of ketamine or a placebo. For 71% of those receiving the real deal, depression improved within a single day. Indeed, 29% became nearly free symptom free. Thirty-five percent of patient
A growing body of preclinical research suggests that brain glutamate systems may be involved in the pathophysiology of major depression and the mechanism of action of antidepressants. This is the first placebo-controlled, double-blinded trial to assess th
Ketamine is now being hailed by scientists as a breakthrough treatment for severe depressives. New research has found that patients who have failed to respond to more conventional drugs can be cured of depression within as little as two hours with an inje