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1Decreased contractility due to energy deprivation in a transgenic rat model of hypertrophic cardiomyopathy.
M. Luedde, U. Flögel, M. Knorr, C. Grundt, H. Hippe, B. Brors, D. Frank, U. Haselmann, C. Antony, M. Voelkers and 5 other author(s). J Mol Med (Berl), 87 (4): 411--422 (April 2009)
10 years ago by @bbrors
show all tags
Adenosine
Animal;
Animals;
Arrhythmias,
Cardiac,
Cardiomyopathy,
Cell
Cells,
Chain
Contraction,
Cultured;
Disease
Disease;
Electron;
Energy
Expression
Gene
Genetic
Heart,
Humans;
Hypertrophic,
Imaging,
Magnetic
Metabolism,
Microscopy,
Mitochondria,
Models,
Muscle
Mutation;
Myocardium,
Myocytes,
Phosphocreatine,
Polymerase
Predisposition
Profiling;
Rats,
Rats;
Reaction;
Resonance
Reverse
Size;
Sprague-Dawley;
T,
Transcriptase
Transgenic;
Triphosphate,
Troponin
cytology/metabolism/physiology;
genetics
genetics/metabolism/physiopathology;
genetics/physiology;
genetics/physiopathology;
metabolism/pathology;
metabolism;
methods;
to
ultrastructure;
AdenosineAnimal;Animals;Arrhythmias,Cardiac,Cardiomyopathy,CellCells,ChainContraction,Cultured;DiseaseDisease;Electron;EnergyExpressionGeneGeneticHeart,Humans;Hypertrophic,Imaging,MagneticMetabolism,Microscopy,Mitochondria,Models,MuscleMutation;Myocardium,Myocytes,Phosphocreatine,PolymerasePredispositionProfiling;Rats,Rats;Reaction;ResonanceReverseSize;Sprague-Dawley;T,TranscriptaseTransgenic;Triphosphate,Troponincytology/metabolism/physiology;geneticsgenetics/metabolism/physiopathology;genetics/physiology;genetics/physiopathology;metabolism/pathology;metabolism;methods;toultrastructure;
(0)
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1Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function
J. Schmitt, E. Debold, F. Ahmad, A. Armstrong, A. Frederico, D. Conner, U. Mende, M. Lohse, D. Warshaw, C. Seidman and 1 other author(s). Proc Natl Acad Sci U S A, 103 (39): 14525-30 (September 2006)Schmitt, Joachim P Debold, Edward P Ahmad, Ferhaan Armstrong, Amy Frederico, Andrea Conner, David A Mende, Ulrike Lohse, Martin J Warshaw, David Seidman, Christine E Seidman, J G Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14525-30. Epub 2006 Sep 18..
14 years ago by @pharmawuerz
show all tags
Actins/metabolism
Animal
Animals
Biomechanics
Cardiac
Cardiac/cytology
Cardiomyopathy,
Dilated/*metabolism/ultrasonography
Disease
Echocardiography
Heterozygote
Homozygote
Mice
Missense/*genetics
Models,
Molecular
Motor
Mutant
Mutation,
Myocardium/cytology/pathology
Myocytes,
Myosins/chemistry/*genetics
Protein
Proteins/metabolism
Secondary
Structure,
Actins/metabolismAnimalAnimalsBiomechanicsCardiacCardiac/cytologyCardiomyopathy,Dilated/*metabolism/ultrasonographyDiseaseEchocardiographyHeterozygoteHomozygoteMiceMissense/*geneticsModels,MolecularMotorMutantMutation,Myocardium/cytology/pathologyMyocytes,Myosins/chemistry/*geneticsProteinProteins/metabolismSecondaryStructure,
(0)
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2Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling
V. Nikolaev, M. Bunemann, E. Schmitteckert, M. Lohse, and S. Engelhardt. Circ Res, 99 (10): 1084-91 (November 2006)Nikolaev, Viacheslav O Bunemann, Moritz Schmitteckert, Eva Lohse, Martin J Engelhardt, Stefan Research Support, Non-U.S. Gov't United States Circulation research Circ Res. 2006 Nov 10;99(10):1084-91. Epub 2006 Oct 12..
14 years ago by @pharmawuerz
show all tags
AMP/genetics/*metabolism
Adrenergic
Animals
Biosensing
Cardiac/cytology/*metabolism
Channels/biosynthesis/genetics/metabolism
Cyclic
Diester
Energy
Fluorescence
Humans
Hydrolases/metabolism
Ion
Isoenzymes/metabolism
Mice
Models,
Molecular
Myocytes,
Phosphoric
Protein
Resonance
Signal
Structure,
Techniques/methods
Tertiary
Transduction
Transfer/methods
Transgenic
beta-1/*metabolism
beta-2/*metabolism
beta-Agonists/pharmacology
Receptor
AMP/genetics/*metabolismAdrenergicAnimalsBiosensingCardiac/cytology/*metabolismChannels/biosynthesis/genetics/metabolismCyclicDiesterEnergyFluorescenceHumansHydrolases/metabolismIonIsoenzymes/metabolismMiceModels,MolecularMyocytes,PhosphoricProteinResonanceSignalStructure,Techniques/methodsTertiaryTransductionTransfer/methodsTransgenicbeta-1/*metabolismbeta-2/*metabolismbeta-Agonists/pharmacologyReceptor
(0)
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2Effects of two Gbetagamma-binding proteins--N-terminally truncated phosducin and beta-adrenergic receptor kinase C terminus (betaARKct)--in heart failure
Z. Li, K. Laugwitz, K. Pinkernell, I. Pragst, C. Baumgartner, E. Hoffmann, K. Rosport, G. Munch, A. Moretti, J. Humrich and 2 other author(s). Gene Ther, 10 (16): 1354-61 (August 2003)Li, Z Laugwitz, K-L Pinkernell, K Pragst, I Baumgartner, C Hoffmann, E Rosport, K Munch, G Moretti, A Humrich, J Lohse, M J Ungerer, M England Gene therapy Gene Ther. 2003 Aug;10(16):1354-61..
14 years ago by @pharmawuerz
show all tags
&
AMP-Dependent
AMP/metabolism
Adenoviridae/genetics
Animal
Animals
Artificial
C
Cardiac
Cardiac/metabolism
Contraction
Cyclic
Eye
Failure/*therapy
GTP-Binding
Gene
Genetic
Heart
Heterotrimeric
Humans
Kinases
Kinases/*genetics
Models,
Myocardial
Myocardium/*metabolism
Myocytes,
Pacing,
Phospholipases/metabolism
Phosphoproteins/*genetics
Protein
Proteins/*genetics
Proteins/metabolism
Rabbits
Receptor
Regulators
Therapy/*methods
Type
Vectors/administration
beta-Adrenergic
dosage
&AMP-DependentAMP/metabolismAdenoviridae/geneticsAnimalAnimalsArtificialCCardiacCardiac/metabolismContractionCyclicEyeFailure/*therapyGTP-BindingGeneGeneticHeartHeterotrimericHumansKinasesKinases/*geneticsModels,MyocardialMyocardium/*metabolismMyocytes,Pacing,Phospholipases/metabolismPhosphoproteins/*geneticsProteinProteins/*geneticsProteins/metabolismRabbitsReceptorRegulatorsTherapy/*methodsTypeVectors/administrationbeta-Adrenergicdosage
(0)
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2Cytoplasmic cAMP concentrations in intact cardiac myocytes
R. Iancu, G. Ramamurthy, S. Warrier, V. Nikolaev, M. Lohse, S. Jones, and R. Harvey. Am J Physiol Cell Physiol, 295 (2): C414-22 (August 2008)Iancu, Radu V Ramamurthy, Gopalakrishnan Warrier, Sunita Nikolaev, Viacheslav O Lohse, Martin J Jones, Stephen W Harvey, Robert D Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States American journal of physiology. Cell physiology Am J Physiol Cell Physiol. 2008 Aug;295(2):C414-22. Epub 2008 Jun 11..
14 years ago by @pharmawuerz
show all tags
&
1-Methyl-3-isobutylxanthine/pharmacology
AMP/analysis/*metabolism
Acetylcholine/pharmacology
Adrenergic
Animals
Biological
Biosensing
Cardiac/cytology/drug
Cell
Compartmentation
Computer
Cultured
Cyclic
Cytoplasm/*metabolism
Energy
Exchange
Factors/genetics/metabolism
Fluorescence
Guanine
Guinea
Luminescent
M2/agonists
Models,
Muscarinic
Myocytes,
Nucleotide
Pigs
Proteins/genetics/metabolism
Resonance
Signal
Simulation
Techniques
Transduction/*physiology
Transfection
Transfer
beta-1/antagonists
beta-Agonists/pharmacology
effects/*metabolism
inhibitors
Receptor
&1-Methyl-3-isobutylxanthine/pharmacologyAMP/analysis/*metabolismAcetylcholine/pharmacologyAdrenergicAnimalsBiologicalBiosensingCardiac/cytology/drugCellCompartmentationComputerCulturedCyclicCytoplasm/*metabolismEnergyExchangeFactors/genetics/metabolismFluorescenceGuanineGuineaLuminescentM2/agonistsModels,MuscarinicMyocytes,NucleotidePigsProteins/genetics/metabolismResonanceSignalSimulationTechniquesTransduction/*physiologyTransfectionTransferbeta-1/antagonistsbeta-Agonists/pharmacologyeffects/*metabolisminhibitorsReceptor
(0)
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2alpha(1)-adrenoceptors in the heart - friend or foe?
L. Hein, and J. Schmitt. J Mol Cell Cardiol, 35 (10): 1183-5 (October 2003)Hein, Lutz Schmitt, Joachim P Comment Editorial England Journal of molecular and cellular cardiology J Mol Cell Cardiol. 2003 Oct;35(10):1183-5..
14 years ago by @pharmawuerz
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Animals
Biological
Calcium/metabolism
Cardiac/metabolism
Deletion
Gene
Heart/physiology
Humans
Knockout
Male
Mice
Models,
Myocytes,
Norepinephrine/metabolism
Transgenic
alpha-1/metabolism/*physiology
Receptor
Adrenergic
AnimalsBiologicalCalcium/metabolismCardiac/metabolismDeletionGeneHeart/physiologyHumansKnockoutMaleMiceModels,Myocytes,Norepinephrine/metabolismTransgenicalpha-1/metabolism/*physiologyReceptorAdrenergic
(0)
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1Rapid activation of the cardiac ryanodine receptor by submillisecond calcium stimuli.
A. Zahradn�kov�, I. Zahradn�k, I. Gy�rke, and S. Gy�rke. J. Gen. Physiol., 114 (6): 787--798 (December 1999)
16 years ago by @hake
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10578015
Acetic
Acids,
Agents,
Algorithms,
Animals,
Bilayers,
Biological,
Calcium
Calcium,
Cardiac,
Cells,
Channel
Channel,
Chelating
Cultured,
Dogs,
Dose-Response
Drug,
Ethylenediamines,
Gating,
Gov't,
Heart,
In
Ion
Kinetics,
Lipid
Magnesium,
Microsomes,
Models,
Myocardium,
Myocytes,
Non-U.S.
P.H.S.,
Patch-Clamp
Photolysis,
Receptor
Relationship,
Release
Research
Reticulum,
Ryanodine
Sarcoplasmic
Signaling,
Support,
Techniques,
U.S.
Vitro,
10578015AceticAcids,Agents,Algorithms,Animals,Bilayers,Biological,CalciumCalcium,Cardiac,Cells,ChannelChannel,ChelatingCultured,Dogs,Dose-ResponseDrug,Ethylenediamines,Gating,Gov't,Heart,InIonKinetics,LipidMagnesium,Microsomes,Models,Myocardium,Myocytes,Non-U.S.P.H.S.,Patch-ClampPhotolysis,ReceptorRelationship,ReleaseResearchReticulum,RyanodineSarcoplasmicSignaling,Support,Techniques,U.S.Vitro,
(0)
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1Kinetics of calcium spikes in rat cardiac myocytes.
A. Zahradn�kov�, E. Pol�kov�, I. Zahradn�k, and A. Zahradn�kov�. J. Physiol., 578 (Pt 3): 677--691 (February 2007)
16 years ago by @hake
show all tags
Animals;
Cal;
Calcium
Calcium;
Cardiac;
Channel;
Dyes;
Factors;
Fluorescent
Male;
Membrane
Models,
Myocytes,
Potentials;
Rats,
Rats;
Receptor
Release
Ryanodine
Signaling
Theoretical;
Time
Wistar;
cium
Animals;Cal;CalciumCalcium;Cardiac;Channel;Dyes;Factors;FluorescentMale;MembraneModels,Myocytes,Potentials;Rats,Rats;ReceptorReleaseRyanodineSignalingTheoretical;TimeWistar;cium
(0)
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1Activation of calcium release assessed by calcium release-induced inactivation of calcium current in rat cardiac myocytes.
A. Zahradn�kov�, Z. Kubalov�, J. Pavelkov�, S. Gy�rke, and I. Zahradn�k. Am. J. Physiol. Cell Physiol., 286 (2): C330--C341 (February 2004)
16 years ago by @hake
show all tags
14522820
Animals,
Calcium
Calcium,
Cardiac,
Cardiovascular,
Channel,
Channels,
Conductivity,
Electric
Gov't,
Male,
Models,
Myocytes,
Non-U.S.
P.H.S.,
Patch-Clamp
Rats,
Receptor
Release
Research
Ryanodine
Stimulation,
Support,
Techniques,
U.S.
Wistar,
14522820Animals,CalciumCalcium,Cardiac,Cardiovascular,Channel,Channels,Conductivity,ElectricGov't,Male,Models,Myocytes,Non-U.S.P.H.S.,Patch-ClampRats,ReceptorReleaseResearchRyanodineStimulation,Support,Techniques,U.S.Wistar,
(0)
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1The ongoing journey to understand heart function through integrative modeling.
R. Winslow, and J. Greenstein. Circ. Res., 95 (12): 1135--1136 (December 2004)
16 years ago by @hake
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15528464
AMP-Dependent
Acid
Action
Adaptor
Adrenergic,
Amino
Animals,
Biological,
Calcium
Cardiac,
Cardiovascular,
Cells,
Channels,
Complexes,
Computer
Conduction
Cyclic
Expression
Extramural,
Gene
Gov't,
Heart
Humans,
Interaction
Kinases,
L-Type,
Long
Mapping,
Models,
Multiprotein
Muscle
Myocardium,
Myocytes,
N.I.H.,
Non-U.S.
P.H.S.,
Phosphatase,
Phosphoprotein
Post-Translational,
Potassium
Potentials,
Processing,
Profiling,
Protein
Proteins,
Proteome,
Proteomics,
QT
Receptors,
Regulation,
Relationship,
Research
Signal
Simulation,
Structure-Activity
Substitution,
Support,
Syndrome,
System,
Transducing,
Transduction,
U.S.
Voltage-Gated,
beta-1,
15528464AMP-DependentAcidActionAdaptorAdrenergic,AminoAnimals,Biological,CalciumCardiac,Cardiovascular,Cells,Channels,Complexes,ComputerConductionCyclicExpressionExtramural,GeneGov't,HeartHumans,InteractionKinases,L-Type,LongMapping,Models,MultiproteinMuscleMyocardium,Myocytes,N.I.H.,Non-U.S.P.H.S.,Phosphatase,PhosphoproteinPost-Translational,PotassiumPotentials,Processing,Profiling,ProteinProteins,Proteome,Proteomics,QTReceptors,Regulation,Relationship,ResearchSignalSimulation,Structure-ActivitySubstitution,Support,Syndrome,System,Transducing,Transduction,U.S.Voltage-Gated,beta-1,
(0)
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1A probability density approach to modeling local control of calcium-induced calcium release in cardiac myocytes.
G. Williams, M. Huertas, E. Sobie, M. Jafri, and G. Smith. Biophys. J., 92 (7): 2311--2328 (April 2007)
16 years ago by @hake
show all tags
Action
Calcium
Calcium;
Cardiac;
Cardiovascular;
Channels;
Computer
Contraction;
Distributions
Models,
Myocardial
Myocytes,
Potentials;
Signaling;
Simulation;
Statistical
Statistical;
ActionCalciumCalcium;Cardiac;Cardiovascular;Channels;ComputerContraction;DistributionsModels,MyocardialMyocytes,Potentials;Signaling;Simulation;StatisticalStatistical;
(0)
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1Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.
C. Weber, K. Ginsburg, K. Philipson, T. Shannon, and D. Bers. J. Gen. Physiol., 117 (2): 119--131 (February 2001)
16 years ago by @hake
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11158165
ATPase,
Action
Adrenergic
Allosteric
Animals,
Biological
Biological,
Caffeine,
Calcium
Calcium,
Cardiac,
Cardiovascular,
Cell
Cells,
Channels,
Computer
Congestive,
Contraction,
Cultured,
Cytosol,
Diastole,
Dogs,
Electric
Exchanger,
Failure,
Ferrets,
Fibers,
Gov't,
Heart
Heart,
Humans,
Ion
Isoproterenol,
Kinetics,
Membrane
Membrane,
Mice,
Models,
Muscle
Mutagenesis,
Myocardial
Myocardium,
Myocytes,
Nickel,
Non-U.S.
P.H.S.,
Potentials,
Rabbits,
Regulation,
Research
Reticulum,
Sarcoplasmic
Signaling,
Simulation,
Sodium-Calcium
Stimulation,
Support,
Tetracaine,
Transport,
U.S.
Ventricles,
beta-Agonists,
{C}a$^{2+}$-Transporting
11158165ATPase,ActionAdrenergicAllostericAnimals,BiologicalBiological,Caffeine,CalciumCalcium,Cardiac,Cardiovascular,CellCells,Channels,ComputerCongestive,Contraction,Cultured,Cytosol,Diastole,Dogs,ElectricExchanger,Failure,Ferrets,Fibers,Gov't,HeartHeart,Humans,IonIsoproterenol,Kinetics,MembraneMembrane,Mice,Models,MuscleMutagenesis,MyocardialMyocardium,Myocytes,Nickel,Non-U.S.P.H.S.,Potentials,Rabbits,Regulation,ResearchReticulum,SarcoplasmicSignaling,Simulation,Sodium-CalciumStimulation,Support,Tetracaine,Transport,U.S.Ventricles,beta-Agonists,{C}a$^{2+}$-Transporting
(0)
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1Activation properties of Kv4.3 channels: time, voltage and K$^+$o dependence.
S. Wang, V. Bondarenko, Y. Qu, M. Morales, R. Rasmusson, and H. Strauss. J. Physiol., 557 (Pt 3): 705--717 (June 2004)
16 years ago by @hake
show all tags
.,
Acid
Action
Active,
Alignment,
Amino
Animals,
Binding
Binding,
Biological
Biological,
Biology,
Calcium
Calcium,
Cardiac,
Cardiovascular,
Chains,
Channel
Channels,
Chemical,
Chloride
Chromatography,
Clocks,
Comparative
Complementary,
Computational
Computer
Conductivity,
DNA,
Data,
Delayed
Dynamics,
Electric
Electrophoresis,
Electrophysiology,
Escherichia
Extramural,
Female,
Gating,
Gel,
Gov't,
High
Homeostasis,
Humans,
Inhibition,
Ion
Kinetics,
L-Type,
Liquid,
Markov
Membrane
Mice,
Models,
Molecular
Myocytes,
N.I.H.,
Nerve
Net,
Neural
Neurological,
Neurons,
Non-P.H.S,
Non-P.H.S.,
Non-U.S.
Nonlinear
Oligonucleotides,
Oocytes,
P.H.S.,
Patch-Clamp
Plasmids,
Polyacrylamide
Potassium
Potassium,
Potential,
Potentials,
Pressure
Protein
Proteins,
RNA,
Recombinant
Rectifier
Research
Reticulum,
Sarcoplasmic
Sequence
Sequence,
Shal
Simulation,
Sites,
Sodium
Software,
Spider
Stimulation,
Structure,,
Study,
Support,
Techniques,
Tertiary,
Transport,
Venoms,
coli,
.,AcidActionActive,Alignment,AminoAnimals,BindingBinding,BiologicalBiological,Biology,CalciumCalcium,Cardiac,Cardiovascular,Chains,ChannelChannels,Chemical,ChlorideChromatography,Clocks,ComparativeComplementary,ComputationalComputerConductivity,DNA,Data,DelayedDynamics,ElectricElectrophoresis,Electrophysiology,EscherichiaExtramural,Female,Gating,Gel,Gov't,HighHomeostasis,Humans,Inhibition,IonKinetics,L-Type,Liquid,MarkovMembraneMice,Models,MolecularMyocytes,N.I.H.,NerveNet,NeuralNeurological,Neurons,Non-P.H.S,Non-P.H.S.,Non-U.S.NonlinearOligonucleotides,Oocytes,P.H.S.,Patch-ClampPlasmids,PolyacrylamidePotassiumPotassium,Potential,Potentials,PressureProteinProteins,RNA,RecombinantRectifierResearchReticulum,SarcoplasmicSequenceSequence,ShalSimulation,Sites,SodiumSoftware,SpiderStimulation,Structure,,Study,Support,Techniques,Tertiary,Transport,Venoms,coli,
(0)
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1Synergistic interactions between Ca$^2+$ entries through L-type Ca$^2+$ channels and Na$^+$-Ca$^2+$ exchanger in normal and failing rat heart.
S. Viatchenko-Karpinski, D. Terentyev, L. Jenkins, L. Lutherer, and S. Gy�rke. J. Physiol., 567 (Pt 2): 493--504 (September 2005)
16 years ago by @hake
show all tags
15975978
Allosteric
Animals,
Binding
Biological,
Calcium
Calcium,
Cardiac
Cardiac,
Cardiomyopathies,
Cell
Cells,
Channel
Channel,
Channels,
Chronic
Comparative
Cultured,
Disease,
Dogs,
Dose-Response
Drug,
Exchanger,
Extramural,
Gating,
Gov't,
Heart,
Ion
L-Type,
Low,
Male,
Membrane,
Models,
Muscle
Mutant
Myocardium,
Myocytes,
N.I.H.,
Non-U.S.
Output,
P.H.S.,
Proteins,
Rats,
Receptor
Regulation,
Relationship,
Release
Research
Reticulum,
Ryanodine
Sarcoplasmic
Signaling,
Sites,
Sodium-Calcium
Sprague-Dawley,
Study,
Support,
Theor,
U.S.
etical,
15975978AllostericAnimals,BindingBiological,CalciumCalcium,CardiacCardiac,Cardiomyopathies,CellCells,ChannelChannel,Channels,ChronicComparativeCultured,Disease,Dogs,Dose-ResponseDrug,Exchanger,Extramural,Gating,Gov't,Heart,IonL-Type,Low,Male,Membrane,Models,MuscleMutantMyocardium,Myocytes,N.I.H.,Non-U.S.Output,P.H.S.,Proteins,Rats,ReceptorRegulation,Relationship,ReleaseResearchReticulum,RyanodineSarcoplasmicSignaling,Sites,Sodium-CalciumSprague-Dawley,Study,Support,Theor,U.S.etical,
(0)
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1Spatial and temporal Ca2+, Mg2+, and ATP2- dynamics in cardiac dyads during calcium release.
I. Valent, A. Zahradn�kov�, J. Pavelkov�, and I. Zahradn�k. Biochim Biophys Acta, 1768 (1): 155--166 (January 2007)
16 years ago by @hake
show all tags
Adenosine
Animals;
Calcium
Cardiac,
Cardiovascular;
Channel,
Computer
Cytosol,
Design;
Diffusion;
Humans;
Kinetics;
Magnesium,
Models,
Myocytes,
Receptor
Release
Research
Reticulum,
Ryanodine
Sarcoplasmic
Signaling;
Simulation;
Triphosphate,
metabolism
metabolism;
AdenosineAnimals;CalciumCardiac,Cardiovascular;Channel,ComputerCytosol,Design;Diffusion;Humans;Kinetics;Magnesium,Models,Myocytes,ReceptorReleaseResearchReticulum,RyanodineSarcoplasmicSignaling;Simulation;Triphosphate,metabolismmetabolism;
(0)
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1Redox modification of ryanodine receptors contributes to sarcoplasmic reticulum Ca2+ leak in chronic heart failure.
D. Terentyev, I. Gy�rke, A. Belevych, R. Terentyeva, A. Sridhar, Y. Nishijima, E. de Blanco, S. Khanna, C. Sen, A. Cardounel and 2 other author(s). Circ Res, 103 (12): 1466--1472 (December 2008)
16 years ago by @hake
show all tags
Animal;
Animals;
Calcium
Calcium,
Cardiac,
Channel,
Chronic
Disease
Disease;
Dogs;
Failure,
Heart
Models,
Myocytes,
Oxidation-Reduction;
Oxidative
Oxygen
Post-Translational,
Processing,
Protein
Reactive
Receptor
Release
Reticulum,
Ryanodine
Sarcoplasmic
Species,
Stress,
adverse
effects/metabolism;
etiology/metabolism/pathology;
metabolism/pathology
metabolism/pathology;
metabolism;
physiology;
Animal;Animals;CalciumCalcium,Cardiac,Channel,ChronicDiseaseDisease;Dogs;Failure,HeartModels,Myocytes,Oxidation-Reduction;OxidativeOxygenPost-Translational,Processing,ProteinReactiveReceptorReleaseReticulum,RyanodineSarcoplasmicSpecies,Stress,adverseeffects/metabolism;etiology/metabolism/pathology;metabolism/pathologymetabolism/pathology;metabolism;physiology;
(0)
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1Triadin overexpression stimulates excitation-contraction coupling and increases predisposition to cellular arrhythmia in cardiac myocytes.
D. Terentyev, S. Cala, T. Houle, S. Viatchenko-Karpinski, I. Gyorke, R. Terentyeva, S. Williams, and S. Gyorke. Circ. Res., 96 (6): 651--658 (April 2005)
16 years ago by @hake
show all tags
Adenoviridae,
Animals;
Arrhythmias,
Bilayers;
Calcium
Calcium,
Calcium-Binding
Cardiac,
Cardiovascular;
Carrier
Channel
Channel,
Contraction,
Dogs;
Electric
Expression;
Function
Fusion
Gating,
Gene
Genetic
Ion
Lipid
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biosynthesis/chemistry/genetics/physiology;
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genetics/physiopathology;
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Adenoviridae,Animals;Arrhythmias,Bilayers;CalciumCalcium,Calcium-BindingCardiac,Cardiovascular;CarrierChannelChannel,Contraction,Dogs;ElectricExpression;FunctionFusionGating,GeneGeneticIonLipidMacromolecularMale;MembraneMicrosomes,MixedModels,MuscleMyocardialMyocytes,Oxygenases,Potentials;ProteinProteins,Rats,Rats;ReceptorRecombinantReleaseReticulum,RyanodineSarcoplasmicSignaling,Sprague-Dawley;Stimulation;Structure,Substances;Tertiary;Transduction,Vectors,biosynthesis/chemistry/genetics/physiology;chemistry/physiology;genetics/physiopathology;genetics;metabolism;physiology/ultrastructure;physiology;
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1The role of stochastic and modal gating of cardiac L-type Ca$^2+$ channels on early after-depolarizations.
A. Tanskanen, J. Greenstein, B. O'Rourke, and R. Winslow. Biophys. J., 88 (1): 85--95 (January 2005)
16 years ago by @hake
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15501946
AMP-Dependent
Acid
Action
Adaptor
Adrenergic,
Algorithms,
Amino
Animals,
Biological,
Biophysics,
Calcium
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{C}a$^{2+}$-Calmodulin
15501946AMP-DependentAcidActionAdaptorAdrenergic,Algorithms,AminoAnimals,Biological,Biophysics,CalciumCalcium,Cardiac,Cardiovascular,Cells,Chains,Channels,Complexes,ComputerConductionCyclicDependentDogs,Electrophysiology,ExpressionExtramural,Factors,GeneGov't,GuineaHeartHumans,InteractionIons,Isoproterenol,Kinase,Kinases,L-Type,LongMapping,MarkovMembraneModels,MultiproteinMuscleMyocardium,Myocytes,N.I.H.,Neurons,Non-U.S.P.H.S.,Phosphatase,PhosphoproteinPhosphorylation,Pigs,Post-Translational,PotassiumPotentials,Processes,Processing,Profiling,ProteinProteins,Proteome,Proteomics,QTReceptors,Regulation,Relationship,ResearchRyanodine,SignalSimulation,StochasticStructure-ActivitySubstitution,Support,Syndrome,System,TimeTransducing,Transduction,U.S.Voltage-Gated,beta-1,{C}a$^{2+}$-Calmodulin
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1An operator splitting method for solving the bidomain equations coupled to a volume conductor model for the torso
J. Sundnes, G. Lines, and A. Tveito. Mathematical biosciences, 194 (2): 233--248 (April 2005)
16 years ago by @hake
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15854678
Algorithms,
Body
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Cardiac,
Cardiovascular,
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Conduction
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15854678Algorithms,BodyCapacitance,Cardiac,Cardiovascular,ComparativeComputerConductionConductivity,ElectricElectrocardiography,Electrochemistry,Electrophysiology,Endocardium,Gov't,HeartHeart,Humans,Ischemia,Mapping,Models,MyocardialMyocytes,Neurological,Non-U.S.PotentialResearchSimulation,Study,Support,SurfaceSynapticSystem,Transmission,Ventricles,
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1Continuum diffusion reaction rate calculations of wild-type and mutant mouse acetylcholinesterase: adaptive finite element analysis.
Y. Song, Y. Zhang, C. Bajaj, and N. Baker. Biophys. J., 87 (3): 1558--1566 (September 2004)
16 years ago by @hake
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,
15345536
Acetylcholine,
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alpha-1,
alpha-Agonists,
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ysis,
,15345536Acetylcholine,Acetylcholinesterase,Activation,AdrenergicAdrenergic,Alcohols,Anal,Animals,Antigen,Antigens,BindingBinding,Cardiac,CellCells,Chemical,ComparativeComplexes,Compounds,ComputerConformation,Crystallization,Crystallography,Cultured,Diffusion,Dioxanes,Dose-ResponseDrug,ElementEnlargement,Factors,FiniteGov't,Hemiterpenes,Humans,Indoles,Ions,Kinetics,Leucine,Ligands,Line,LymphocyteMice,Models,Molecular,MultiproteinMuscleMutation,Myocytes,Newborn,Non-P.H.S.,Non-U.S.Norepinephrine,OrganophosphorusP.H.S.,Piperazines,Prazosin,ProteinProteins,Rats,Receptors,Relationship,ReproducibilityResearchResults,Simulation,Sites,Sprague-Dawley,Statistical,Stereoisomerism,Study,Subsets,Support,T-Cell,T-LymphocyteTheoretical,TimeTumor,U.S.alpha-1,alpha-Agonists,alpha-Antagonists,gamma-delta,ofysis,
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1Decreased contractility due to energy deprivation in a transgenic rat model of hypertrophic cardiomyopathy.

1Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function

2Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling

2Effects of two Gbetagamma-binding proteins--N-terminally truncated phosducin and beta-adrenergic receptor kinase C terminus (betaARKct)--in heart failure

2Cytoplasmic cAMP concentrations in intact cardiac myocytes

2alpha(1)-adrenoceptors in the heart - friend or foe?

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1Kinetics of calcium spikes in rat cardiac myocytes.

1Activation of calcium release assessed by calcium release-induced inactivation of calcium current in rat cardiac myocytes.

1The ongoing journey to understand heart function through integrative modeling.

1A probability density approach to modeling local control of calcium-induced calcium release in cardiac myocytes.

1Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.

1Activation properties of Kv4.3 channels: time, voltage and K$^+$o dependence.

1Synergistic interactions between Ca$^2+$ entries through L-type Ca$^2+$ channels and Na$^+$-Ca$^2+$ exchanger in normal and failing rat heart.

1Spatial and temporal Ca2+, Mg2+, and ATP2- dynamics in cardiac dyads during calcium release.

1Redox modification of ryanodine receptors contributes to sarcoplasmic reticulum Ca2+ leak in chronic heart failure.

1Triadin overexpression stimulates excitation-contraction coupling and increases predisposition to cellular arrhythmia in cardiac myocytes.

1The role of stochastic and modal gating of cardiac L-type Ca$^2+$ channels on early after-depolarizations.

1An operator splitting method for solving the bidomain equations coupled to a volume conductor model for the torso

1Continuum diffusion reaction rate calculations of wild-type and mutant mouse acetylcholinesterase: adaptive finite element analysis.

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