Ampakines capable of improving cognition by enhancing brain activity under normal circumstances may also have the potential to reduce the harmful or unwanted effects of sleep deprivation. (CX717 by Cortex Pharmaceuticals)
J Clin Psychiatry 2000 May;61(5):378-81 Modafinil augmentation of antidepressant treatment in depression. Menza MA, Kaufman KR, Castellanos A Department of Psychiatry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical Sch
Rapidly restores vigilance and alertness in older people and the physically and mentally tired. Has a powerful antidepressant action far superior to that of fluoxetine (Prozac) and clomipramine (Anafranil) and is without any serious side effects. Adrafin
The effect of Adrafinil, unlike conventional stimulants, builds subtly over a period of days to months. This appears to be based on its ability to selectively stimulate adrenergic receptors in the brain. These receptors normally respond to norepinephrine