The authors performed a target trial emulation to compare the risk of mania among individuals with bipolar depression treated or not treated with antidepressants over a 1-year period. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
In this issue of the Journal, Rohde and colleagues (9) present the results of a “target trial emulation” designed to assess the risk of antidepressant-induced mania in bipolar depression. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
As cannabis policies become more permissive, there is a reasonable concern that this may increase rates of CUD and contribute further to the incidence of other mental health disorders. However, several strategies can be implemented to offset these harms.
Globally, the bipolar disorder-related prevalent cases, incident cases and number of YLDs all increased from 1990 to 2019. Regionally, the World Health Organization Region of the Americas accounted for the highest estimated YLD number and rate, with the highest age-standardised prevalence rate in 1990 and 2019 and highest EAPC of prevalence. By sociodemographic index (SDI) quintiles, all five SDI regions saw an increase in estimated incident cases. Nationally, New Zealand reported the highest age-standardised rate of incidence, prevalence and YLDs in 1990 and 2019. The most prominent age effect on incidence rate was in those aged 15–19 years. Decreased effects of period on incidence, prevalence and YLD rates was observed overall and in females, not in males. The incidence, prevalence and YLD rates showed an unfavourable trend in the younger cohorts born after 1990, with males reporting a higher cohort risk than females.
To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aims of this study were to investigate secular trends and distribution of body mass index (BMI) among individuals with bipolar disorders and the general population between 2008 and 2019. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Lived experience adaptation of mental health interventions can help ensure that the intervention is appropriate for the target population. This paper describes a youth-led adaptation of a self-stigma reduction intervention for young adults with bipolar spectrum disorders, that is, Narrative Enhancement and Cognitive Therapy.
Clinical guidelines recommend providing physical activity interventions (PAIs) to people with schizophrenia or bipolar disorder for weight management. However, the cost-effectiveness of PAIs is unknown. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
A large body of evidence has demonstrated that exposure to childhood maltreatment at any stage of development can have long-lasting consequences. It is associated with a marked increase in risk for psychiatric and medical disorders. This review summarizes the literature investigating the effects of childhood maltreatment on disease vulnerability for mood disorders, specifically summarizing cross-sectional and more recent longitudinal studies demonstrating that childhood maltreatment is more prevalent and is associated with increased risk for first mood episode, episode recurrence, greater comorbidities, and increased risk for suicidal ideation and attempts in individuals with mood disorders. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Pharmacological treatment patterns for bipolar disorder have changed during recent years, but for better or worse? To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Family history is an established risk factor for mental illness. The authors sought to investigate whether polygenic scores (PGSs) can complement family history to improve identification of risk for major mood and psychotic disorders. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Medication self-management (MSM) is considered an important aspect of pharmacotherapy and plays an essential role in the treatment of various illnesses. To date, research into the willingness and attitude of psychiatric healthcare providers toward MSM in patients diagnosed with schizophrenia or bipolar disorders during hospitalization is lacking. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Early intervention for people diagnosed with bipolar disorder is a priority, but little is known about how recovery from first episode psychotic mania is experienced by this group. This study aimed to explore the experience of recovery from first episode psychotic mania for people diagnosed with bipolar disorder.
There have been limited prospective investigations of early clinical markers involved in mood regulation and diagnosis change in young patients. This study aimed to evaluate the changes in impulsivity and defence mechanisms in patients with major depressive disorder (MDD) and bipolar disorder (BD) with acute symptoms and remission compared to healthy controls (HC), and possible psychological predictors of diagnosis conversion. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The rate of comorbid attention-deficit hyperactivity disorder and bipolar disorder far exceeds chance if the two are independent conditions. Explanations for such a high comorbid prevalence and management implications are considered. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Self-management is one of the cornerstones in the treatment of bipolar disorder (BD). Complementing interventions by apps are seen as a good opportunity to support self-management. However, there is insufficient knowledge about understanding the use of health-related applications by consumers with BD for self-management purposes.
In spite of the recent increase in scientific publications showing an expressive interest in studies about social support, there are still scarce publications regarding this thematic and bipolar disorder, mostly when evaluating the individuals in the state of euthymia. Euthymia referred a state that a bipolar patient does not have signs/symptoms of (hipo)mania or depression, thus assessing individuals in this state may reduce response bias. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
For me, the key implication of the study is that people accessing CAMHS, particularly people who experienced inpatient care in adolescence, should be considered for regular review. Once reaching adulthood, screening and assessment for bipolar and psychosis should be available in the adult mental health services. Hopefully, these measures will limit the duration of non-treatment.
Childhood trauma is negatively associated with depression severity in bipolar disorder; however, the underlying mechanisms remain unclear. We investigated whether personality traits (neuroticism, extraversion, openness, agreeableness, conscientiousness) mediate the relationship between childhood trauma and the severity of bipolar depression. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Attention deficit hyperactivity disorder is a frequent comorbid condition in adults with bipolar disorder. We performed a meta-analysis aimed at assessing sociodemographic and clinical correlates of attention deficit hyperactivity disorder in bipolar disorder.To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Bipolar disorder may undertake a progressive course in a subset of patients, and research efforts have been made to understand the biological basis underlying this process. This systematic review examined the literature available on biological markers associated with illness progression in bipolar disorder.. To read the full article, log in using your MPFT NHS OpenAthens details.