Statins may act on an enzyme called endothelial nitric oxide synthase, which stimulates nitric oxide production. Increased nitric oxide has anti-inflammatory and anti-clotting effects...
Human resolvin E1 inhibits both the migration of inflammatory cells to sites of inflammation and the turning on of other inflammatory cells. Aspirin-triggered resolivins are made from omega-3 fatty acids by cellular enzymes. COX-2 inhibitors also inhibit
paradox that a high-fat, high–saturated fat diet is associated with diminished coronary artery disease progression in women with the metabolic syndrome, a condition that is epidemic in the United States. This paradox presents a challenge to differentiat
Women and Heart Disease The Role of Diabetes and Hyperglycemia Elizabeth Barrett-Connor, MD; Elsa-Grace V. Giardina, MD; Anselm K. Gitt, MD; Uwe Gudat, MD; Helmut O. Steinberg, MD; Diethelm Tschoepe, MD Arch Intern Med. 2004;164:934-942.
A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention)
Results from the first U.S. clinical trial investigating the benefit of using a patient's own (autologous) selected adult stem cells, called CD34+ cells, to treat coronary artery disease are promising.
Martin B. Leon, MD, violated academic ethics of the highest order by leaking results of the COURAGE trial prematurely, denigrating its design, discrediting its results, to protect pocketbooks of interventional cardiologists and stent industry. Sanctions
A major limitation of percutaneous therapy (PCI) for the treatment of chronic total occlusions (CTOs) is the inability to cross with a wire. We report successful recanalization of a CTO using Intraluminal Wire (tm)...
Martin Leon, M.D., a leading interventional cardiologist accused of leaking details of a major study weeks before its scheduled release, was barred today from taking part in next year's American College of Cardiology meeting.
Overweight men and women assigned to drink fructose-sweetened beverages as 25% of their energy intake developed atherogenic lipid profiles in just two weeks; unlike glucose, fructose promotedatherogenic lioproprotein phenotypes and glucose intolerance/ins
Welcome to AskDrWiki.com where you can publish your review articles, clinical notes, pearls, and medical images on the site. Using a wiki anyone with a medical background can contribute or edit medical articles. The Main focus has been on Cardiology and E
Statins exert their pleiotropic effects, in part, by improving endothelial function via up-regulation of endothelial nitric oxide synthase enzyme activity.
Experimental as well as clinical data do not support the hypothesis that atorvastatin or any other statin affects the antithrombotic potency of clopidogrel.
A decrease in the oxidative damage to low-density lipoprotein (LDL) cholesterol is one of the protective mechanisms in which a traditional Mediterranean diet exerts a protective effect on coronary heart disease development.
Dr. Noboru Ashida, Department of Geriatric Medicine, Graduate School of Medicine, Kyoto University, 54 Kawaramachi, Shogoin Sakyo-ku, Kyoto 606-8507, Japan. Voice +81-75-751-3465; fax: +81-75-751-3574; ash@kuhp.kyoto.u.ac.jp.
The morbidity, mortality, expense and transient benefits of a high technology approach toward the coronary disease epidemic, has failed. It is time to realize that the answer to a faulty lifestyle epidemic is not drugs and technology – it is lifestyle.
Our patient exemplified the challenges involved in a CTO, which included the length of the lesion, the lack of a proximal nipple, the presence of a side branch at the occlusion point, poor visualization of the distal vessel despite contralateral injection
S. Pocock, J. McMurray, and T. Collier. Journal of the American College of Cardiology, 66 (23):
2648-62(December 2015)Disseny; RCT; CV; Introductori; Comparacions múltiples; Composite endpoints; Intention to treat; Anàlisi de subgrups.
S. Deb, P. Austin, J. Tu, D. Ko, C. Mazer, A. Kiss, and S. Fremes. The Canadian journal of cardiology, 32 (2):
259-65(February 2016)Propensity score; CV; Introductori<br/><br/>Taula 1 de ATE/ATT per mètode.
B. George, S. Seals, and I. Aban. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 21 (4):
686-94(August 2014)Anàlisi de supervivència; Introductori; SAS.
S. Pocock, T. Clayton, and G. Stone. Journal of the American College of Cardiology, 66 (25):
2886-98(December 2015)Disseny; Dissenys adaptatius; Tests d'equivalència; Early stopping; RCT; Introductori; CV<br/><br/>Molts exemples i bons gràfics.