From hs-CRP results, doctors gain crucial insight into inflammation of the blood vessels around the heart, a factor not considered until now for patients at risk.
In much of the world (but not in the U.S.,) drug-coated stents are avoided by cardiologists because of their high cost. To compensate for the inability to use these stents, many cardiologists outside of the U.S. have taken to administering sirolimus (also
Finnish Medical Society Duodecim. Unstable angina pectoris. In: EBM Guidelines. Evidence-Based Medicine [CD-ROM]. Helsinki, Finland: Duodecim Medical Publications Ltd.; 2006 Mar 15 [Various]
In the Injury Theory, it's damage to the arterial endothelium, followed by platelet activation, then smooth muscle cell migration to injury, then macrophages, with resulting "foam cells." Engorged foam cells burst, starting the injury cycle all over again
it may no longer be enough to measure just HDL levels without determining levels of paroxonase and platelet-activating acetylhydrolase; levels of these enzymes may determine whether HDL is proinflammatory or protective. Likewise, measuring Lp(a) and small
B. George, S. Seals, and I. Aban. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 21 (4):
686-94(August 2014)Anàlisi de supervivència; Introductori; SAS.
S. Deb, P. Austin, J. Tu, D. Ko, C. Mazer, A. Kiss, and S. Fremes. The Canadian journal of cardiology, 32 (2):
259-65(February 2016)Propensity score; CV; Introductori<br/><br/>Taula 1 de ATE/ATT per mètode.
S. Pocock, T. Clayton, and G. Stone. Journal of the American College of Cardiology, 66 (25):
2886-98(December 2015)Disseny; Dissenys adaptatius; Tests d'equivalència; Early stopping; RCT; Introductori; CV<br/><br/>Molts exemples i bons gràfics.
S. Pocock, J. McMurray, and T. Collier. Journal of the American College of Cardiology, 66 (23):
2648-62(December 2015)Disseny; RCT; CV; Introductori; Comparacions múltiples; Composite endpoints; Intention to treat; Anàlisi de subgrups.